list biological laboratories公司是世界的科研毒素试剂供应商,其毒素包括霍乱病毒,蛇毒,百日咳毒素等各类毒素,我公司常年低价供应,货期快.有意者请. 百日咳毒素长期现货供应,货号181及180。
listlabs 177B说明书
炭疽杆菌是炭疽病的病原体。炭疽杆菌产生的主要毒力因子是γ连接的聚-D-谷氨酸胶囊和由三种成分组成的外毒素,保护性抗原(PA),致死因子(LF)和水肿因子(EF)。这些蛋白质不是单*毒的,而是以二元组合起作用。PA(细胞结合成分)与LF(酶部分之一)的复合物被称为“致死毒素”并可导致死亡。PA和酶促EF一起引起皮肤水肿。分泌后,PA被膜肽酶切割,使63kDa羧基末端片段寡聚化成七聚体。切割是暴露EF和LF的结合位点的必要步骤。组装的PA复合物和相关的LF或EF通过胞吞作用进入细胞。PA介导LF和EF向细胞质的转移,其中这些酶识别并蛋白水解其靶标。LF组分是一种锌依赖性金属蛋白酶,可裂解丝裂原活化蛋白激酶激酶(MAPKK),从而削弱其功能,从而阻断MAPK信号通路。EF是钙调蛋白依赖性腺苷酸环化酶,其在细胞中产生过量的环AMP,导致水肿。目前的研究集中于开发有效的疫苗以及筛选LF酶活性的有效抑制剂。
含有炭疽LF切割位点的FRET肽底物可作为MAPKKide®获得,并可用于评估LF的酶活性。
炭疽保护性抗原片段(PA 20)
从炭疽芽孢杆菌
保护性抗原(PA)是炭疽毒素的受体结合成分。原始的83kDa蛋白质被细胞弗林蛋白酶样蛋白酶切割,形成活化的63kDa单体PA63。在这种形式中,PA63与其他PA63分子结合形成环状七聚体。PA63还具有对于与细胞表面上形成的孔相邻的酶LF和EF特异性的结合位点,用于易位。对于醉酒细胞,PA应与EF或LF一起使用约7倍过量。
List Labs提供三种不同大小的PA,产品#171是未切割的83kDa蛋白质,产品#174和175是PA63,它们已被激活和纯化,PA63分别与FITC缀合。另外,我们提供从PA,PA20,产品#177切割的约20kDA片段
#177A(50 ug) - $ 340.00
#177B(0.25毫克) - $ 610.00
货号  | 品名  | 规格  | 价格  | 
list104  | Cholera Toxin B Subunit (Choleragenoid) in low salt1  | 0.5mg  | 4930  | 
list106  | Cholera Toxin B Subunit Fluorescein Isothiocyanate Conjugate (BFITC)  | 0.2mg  | 9775  | 
list112  | Cholera Toxin B Subunit Biotin  | 0.2mg  | 9775  | 
list122  | Enterotoxin Type B from Staphylococcus aureus1,3  | 0.5mg  | 7225  | 
list123  | Enterotoxin Type B Toxoid from Staphylococcus aureus 1,3  | 0.25mg  | 8075  | 
list139  | Botulinum Neurotoxin Type B Toxoid  | 10µg  | 6800  | 
list150  | Diphtheria Toxin, unnicked from Corynebacterium diphtheriae  | 1mg  | 11050  | 
list151  | Diphtheria Toxoid, from Corynebacterium diphtheriae  | 0.5mg  | 10625  | 
list153  | Toxin A Toxoid from Clostridium difficile  | 100µg  | 11900  | 
list156  | Pasteurella Multocida Toxin  | 50µg  | 8075  | 
list160  | Exotoxin A from Pseudomonas aeruginosa  | 1mg  | 4420  | 
list161  | Shiga Toxin 1 from Escherichia coli1,4,8  | 10µg  | 11900  | 
list162  | Shiga Toxin 2 from Escherichia coli1,4,8  | 10µg  | 11050  | 
list174  | Anthrax Protective Antigen, Activated (PA 63) from Bacillus anthracis  | 0.5mg  | 9350  | 
list175  | Anthrax PA 63 - Fluorescein Isothiocyanate Conjugate (PAFITC)  | 50µg  | 7225  | 
list180  | Pertussis Toxin Islet-Activating Protein Lyophilized in buffer  | 50µg  | 5525  | 
list181  | Pertussis Toxin Islet Activating Protein Lyophilized (Salt-Free)  | 50µg  | 5525  | 
list184  | Pertussis Toxin Mutant  | 50µg  | 5525  | 
list186  | FIMBRIAE 2/3 from B. pertussis  | 50µg  | 5950  | 
list187  | Pertactin from Bordetella pertussus (69 kDa Protein)  | 50µg  | 4590  | 
list193  | Tetanus Toxin C Fragment  | 10µg  | 9350  | 
list201  | LPS from Escherichia coli O111:B4  | 5mg  | 3230  | 
list206  | LPS, Escherichia coli 0157:H7  | 10.0mg  | 4760  | 
list225  | LPS from Salmonella typhimurium  | 5mg  | 2890  | 
list301  | LPS from Escherichia coli J5 (Rc)  | 5mg  | 2890  | 
list302  | LPS from Escherichia coli K12, D31m4 (Re)  | 5mg  | 2890  | 
list304  | LPS from Salmonella minnesota R595 (Re)  | 5mg  | 2890  | 
list314  | LPS from Escherichia coli K12 strain LCD25  | 1mg  | 2890  | 
list400  | HPT™ LPS, highly purified from Bordetella Pertussis 165  | 1mg  | 5100  | 
list401  | Lipid A monophosphoryl from Salmonella minnesota R595  | 1mg  | 3400  | 
list421  | Ultra Pure LPS from Escherichia coli O111:B4  | 1mg  | 3570  | 
list423  | Ultra Pure LPS from Escherichia coli O55:B5  | 1mg  | 3570  | 
list433  | LISTÔ HPTÔ, LPS, highly purified Escherichia coli O113 LPS  | 1mg  | 4080  | 
list434  | Ultra Pure LPS from Salmonella minnesota R595 (Re)  | 1mg  | 3400  | 
list520  | SNAPtide® Peptide Substrate (o-Abz/Dnp) (U.S. Patent #6,504,006)  | 200nmoles  | 9775  | 
list521  | SNAPtide® Peptide Substrate (FITC/DABCYL) (U.S. Patent #6,504,006)  | 200nmoles  | 8500  | 
list523  | SNAPtideÒ Peptide Substrate flP6 (DABCYL/5-IAF), U.S. Patent Pending #61/252,675  | 200nmoles  | 8500  | 
list525  | Control Peptide for SNAPtideÒ #520  | 200nmoles  | 8500  | 
list526  | Control Peptide for SNAPtide® #521  | 200nmoles  | 8500  | 
list528  | Unquenched Calibration Peptide for SNAPtide® 521  | 50nmoles  | 2890  | 
list529  | Unquenched Calibration Peptide for SNAPtide® 520  | 50nmoles  | 2890  | 
list530  | MAPKKide® Peptide Substrate (o-Abz/Dnp)  | 200nmoles  | 5100  | 
list531  | MAPKKide® Peptide Substrate (DABCYL/FITC)  | 200nmoles  | 5100  | 
list532  | MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor  | 100nmoles  | 4250  | 
list539  | Unquenched Calibration Peptide for MAPKKideÒ 530  | 50nmoles  | 2890  | 
list540  | VAMPtide® Peptide Substrate (o-Abz/Dnp)  | 200nmoles  | 8500  | 
list541  | VAMPtide® Peptide Substrate (FITC/DABCYL)  | 200nmoles  | 8500  | 
list542  | VAMPtide® Peptide Substrate (PL 150, Pya/Nop)  | 200nmoles  | 8500  | 
list549  | Calibration Fluorophore for VAMPtideÒ 540  | 100nmoles  | 2890  | 
list550  | SNAP Etide® Peptide Substrate (o-Abz/Dnp)  | 100nmoles  | 6800  | 
list560  | SYNTAXtideÒ Peptide Substrate (o-Abz/Dnp) for C. botulinum Type C  | 200nmoles  | 8500  | 
list703  | Anti-Cholera Toxin B Subunit (Goat)  | 0.1ml  | 3060  | 
list752  | Anti-Toxin A from Clostridium difficile (Goat)  | 0.5ml  | 3230  | 
list760  | Anti-Exotoxin A (Goat)  | 0.5ml  | 3400  | 
list781  | Anti-Protective Antigen from Bacillus anthracis (Goat) affinity purified, Liquid6,7  | 0.1mg  | 7055  | 
list100B  | Cholera Toxin (Azide Free)1  | 1mg  | 3400  | 
list101B  | Cholera Toxin1  | 1mg  | 3400  | 
list101C  | Cholera Toxin1  | 2mg  | 5355  | 
list116L  | Alpha Toxin from C. septicum4,6,7  | 50µg  | 4930  | 
list126A  | Epsilon Toxin from C. perfringens1,4,8  | 0.1mg  | 5950  | 
list128A  | Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3  | 10µg  | 2890  | 
list128C  | Botulinum Neurotoxin Type A Complex from Clostridium botulinum1,3  | 100µg  | 5440  | 
list130A  | Botulinum Neurotoxin Type A from Clostridium botulinum1,3  | 10µg  | 5440  | 
list130B  | Botulinum Neurotoxin Type A from Clostridium botulinum1,3  | 100µg  | 13600  | 
list133L  | Botulinum Neurotoxin Type A Toxoid, Liquid6,7  | 10µg  | 5440  | 
list136A  | Botulinum Neurotoxin Type B. from Clostridium botulinum 1,3  | 10µg  | 5100  | 
list136B  | Botulinum Neurotoxin Type B, from Clostridium botulinum1,3  | 100µg  | 17000  | 
list138A  | Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3  | 10µg  | 2890  | 
list138B  | Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum1,3  | 100µg  | 7225  | 
list140A  | Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3  | 10µg  | 2890  | 
list140B  | Botulinum Neurotoxin Type E, Nicked, Complex from Clostridium botulinum1,3  | 100µg  | 8925  | 
list141A  | Botulinum Neurotoxin Type E, Nicked, from Clostridium botulinum1,3  | 10µg  | 8075  | 
list146A  | Botulinum Neurotoxin Type D, Nicked, Recombinant from Clostridium botulinum1,3  | 10µg  | 5355  | 
list149A  | Diphtheria Toxin CRM Mutant  | 0.25 mg  | 8500  | 
list152C  | Toxin A from Clostridium difficile  | 100µg  | 9010  | 
list154A  | Toxin B Toxoid from Clostridium difficile  | 20µg  | 2890  | 
list15  | Toxin B from Clostridium difficile  | 2µg  | 2890  | 
list155B  | Toxin B from Clostridium difficile  | 20µg  | 8500  | 
list155C  | Toxin B from Clostridium difficile  | 200µg  | 15300  | 
list155L  | Toxin B from Clostridium difficile, Liquid6,7  | 50µg  | 9860  | 
list157A  | Binary Toxin from Clostridium difficile, A Subunit  | 20µg  | 5950  | 
list158A  | Binary Toxin from Clostridium difficile, B Subunit  | 40µg  | 5950  | 
list159A  | Glutamate Dehydrogenase (GDH) from Clostridium difficile6,7  | 0.1mg  | 4930  | 
list169A  | Anthrax Lethal Factor (LF-A) , Recombinant from Bacillus anthracis Native Sequence  | 0.1mg  | 3060  | 
list169B  | Anthrax Lethal Factor (LF-A),Recombinant from Bacillus anthracis Native Sequence  | 1mg  | 12750  | 
list169L  | Anthrax Lethal Factor (LF-A),Recomb.from Bacillus anthracis 5,7  | 0.2 mg  | 5950  | 
list171E  | Anthrax Protective Antigen (PA), Recombinant from Bacillus anthracis  | 0.5mg  | 8755  | 
list172B  | Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis  | 1mg  | 12750  | 
list172C  | Anthrax Lethal Factor (LF), Recombinant from Bacillus anthracis  | 10mg  | 39525  | 
list172L  | Lethal Factor, Recomb from Bacillus anthracis, froz liq 5,7  | 1.0 mg  | 12750  | 
list173B  | Anthrax Edema Factor (EF), Recombinant Mutant S447N from Bacillus anthracis  | 0.5mg  | 16150  | 
list176A  | Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis  | 0.1mg  | 5100  | 
list176B  | Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from Bacillus anthracis  | 1mg  | 16150  | 
list177A  | Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis  | 50µg  | 5950  | 
list177B  | Anthrax Protective Antigen Fragment (PA 20) from Bacillus anthracis  | 0.25mg  | 11050  | 
list178A  | Anthrax Edema Factor (EF), Recombinant from Bacillus anthracis  | 0.1mg  | 2890  | 
list179A  | Pertussis Toxin Islet Activating Protein (in glycerol)6,7  | 50µg  | 4845  | 
list188L  | Adenylate Cyclase Toxin from B. pertussis, Recombinant, Frozen Liquid5,7  | 50µg  | 5270  | 
list190A  | Tetanus Toxin2  | 25µg  | 2890  | 
list190B  | Tetanus Toxin2  | 100µg  | 9350  | 
list191A  | Tetanus Toxoid  | 25µg  | 4675  | 
list191B  | Tetanus Toxoid  | 100µg  | 13600  | 
list196A  | C-fragment, FITC Conjugate  | 10µg  | 6800  | 
list203A  | LPS, Escherichia coli O55:B5  | 2.5 mg  | 3060  | 
list500A  | SNAP-25 Recomb Protein Substrate for C. botulinum Type A and E Neurotoxin  | 100µg  | 5525  | 
list510A  | GST Synaptobrevin-2 Protein Recomb. Protein Substrate for C. botulinum Type B,D and F  | 100µg  | 5950  | 
list610A  | Botulinum Neurotoxin Type A Light Chain, Recombinant1  | 10µg  | 4760  | 
list611A  | Botulinum Neurotoxin Type A Light Chain, GST Fusion, Recombinant1  | 15µg  | 4760  | 
list612A  | Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain1  | 50µg  | 4760  | 
list613A  | Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion1  | 50µg  | 4760  | 
list620A  | Botulinum Neurotoxin Type B Light Chain, Recombinant1  | 10µg  | 8500  | 
list622A  | Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain1  | 50µg  | 4760  | 
list623A  | Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion1  | 50µg  | 4760  | 
list62  | Botulinum Neurotoxin Type C Light Chain, Recombinant1  | 10µg  | 8500  | 
list630A  | Botulinum Neurotoxin Type D Light Chain, Recombinant1  | 10µg  | 5695  | 
list650A  | Tetanus Toxin Light Chain, Recombinant  | 10µg  | 3825  | 
list690B  | Receptor for C. botulinum Type A Neurotoxin GST-SV2c luminal domain  | 100nmoles  | 6800  | 
list730A  | Anti-Botulinum Neurotoxin, Type A (Chicken lgY), Liquid6,7  | 0.1mg  | 5610  | 
list731L  | Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Liquid6,7  | 0.1mg  | 5950  | 
list736A  | Anti-Botulinum Type B (Chicken lgY), Liquid6,7  | 0.1mg  | 5950  | 
list753A  | Anti-Clostridium difficile Toxin A (Chicken lgY), Liquid6,7  | 0.1mg  | 5780  | 
list754A  | Anti-Clostridium difficile Toxin B (Chicken lgY), Liquid6,7  | 0.1mg  | 5780  | 
list756A  | Anti-Clostridium difficile Glutamate Dehydrogenase, lgY, Liquid6,7  | 0.1mg  | 5780  | 
list757A  | Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY), Liquid6,7  | 0.1mg  | 5780  | 
list758A  | Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7  | 0.1mg  | 5780  | 
list759A  | Biotinylated Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY), Liquid6,7  | 0.1mg  | 5780  | 
list761L  | Anti-Shiga Toxin 1 (Rabbit), lgG, Liquid6,7  | 0.5mg  | 3400  | 
list765L  | Anti-Shiga Toxin 2 (Rabbit), IgG, Liquid6,7  | 0.5mg  | 2890  | 
list766L  | Anti-Shiga Toxin, Camelid Antibody, VHH, Liquid6,7  | 0.5mg/ml  | 5950  | 
list768L  | Biotinylated Anti-Lethal Factor from B. anthracis, IgY, Liquid6,7  | 0.1mg  | 5950  | 
list769B  | Anti-Lethal Factor from Bacillus anthracis (Chicken lgY), Liquid6,7  | 0.2mg  | 8500  | 
list771B  | Anti-Protective Antigen from Bacillus anthracis (Goat)  | 1mg  | 2890  | 
list772B  | Anti-Lethal Factor from Bacillus anthracis (Goat)  | 1.0 mg  | 2890  | 
list773L  | Anti-Edema Factor from Bacillus anthracis (Goat), Liquid6,7  | 1mg  | 2890  | 
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