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CodexBiosolutions产品目录
点击次数:79 发布时间:2020-12-19

CodexBiosolutions为学术和政府研究机构,制药和生物技术行业提供基于细胞的测定产品和服务。该公司总部位于马里兰州的I-270高科技走廊。CodexBiosolution的核心产品是ACTOne细胞系和膜潜在试剂盒,这些产品已获得BD Biosciences的许可。我们还开发了其他新的基于电池的产品,以满足各种客户的需求。

ACTOne检测原理

ACTOne技术是同类产品中一个以高通量格式提供细胞内cAMP变化的实时信息而无需细胞裂解步骤的技术。该测定法可用于含有专有外源环核苷酸门控(CNG)通道的细胞系。该通道被升高的细胞内cAMP水平激活,导致离子通量(通常可由钙反应性染料检测到)和细胞膜去极化,而荧光膜电势(MP)染料可以检测到。ACTOne cAMP分析可通过FLIPR或荧光酶标仪读取细胞内cAMP变化的终点和动力学。这是一种简单的均相测定法,仅涉及染料和化合物的添加步骤,可轻松在高通量环境中实施。

 

 CodexBiosolutions产品目录

Product NameProduct NoProduct Details
ACTOne Gi-GPCRsCB-80300-XXXACTOne GPCR cell lines
ACTOne Gs-GPCRsCB-80200-XXXACTOne GPCR cell lines
ACTOne Membrane Potential Dye Kit (10-plate)CB-80500-201For ACTOne GPCR and PDE cell based assays
ACTOne Membrane Potential Dye Kit (100-plate)CB-80500-211For ACTOne GPCR and PDE cell based assays
ACTOne PDE10A (cAMP)CB-81200-102PDE10A cell line (cAMP)
ACTOne PDE1B (cAMP)CB-81200-103PDE1B cell line (cAMP)
ACTOne PDE1C (cAMP)CB-81200-104PDE1C (cAMP) cell line
ACTOne PDE4A (cAMP)CB-81200-105PDE4A (cAMP) cell line
ACTOne-PDE1A (cAMP)CB-81200-110PDE1A (cAMP) cell line
ACTOne-PDE1A (cGMP)CB-81300-106<span new="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" zh-cn;="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" en-us;="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" 11pt;="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" roman","serif";="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" "times="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" roman";="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;" ar-sa;'="\&quot;\\&quot;\&quot;'&quot;&quot;'\&quot;\\&quot;\&quot;">PDE1A (cGMP) cell line
ACTOne-PDE1B (cGMP)CB-81300-102PDE1B (cGMP) cell line
ACTOne-PDE1C (cGMP)CB-81300-104PDE1C (cGMP) cell line
ACTOne-PDE2A (cAMP)CB-81200-101PDE2A cell line (cAMP)
ACTOne-PDE4 (cAMP)CB-81200-100PDE4 cell line (cAMP)
ACTOne-PDE4B (cAMP)CB-81200-106PDE4B (cAMP) cell line
ACTOne-PDE4D (cAMP)CB-81200-107PDE4D (cAMP) cell line
ACTOne-PDE5A (cGMP)CB-81300-103PDE5A (cGMP) cell line
ACTOne-PDE9 (cGMP)CB-81300-101PDE9 (cGMP) cell line
Adenosine A1 ReceptorCB-80300-212ACTOne-Gi GPCR Cell Line
Adenosine A2a ReceptorCB-80200-261ACTOne-Gs GPCR Cell Line
Adenosine A2b ReceptorCB-80200-260ACTOne-Gs GPCR Cell Line
Adenosine A3 ReceptorCB-80300-232ACTOne-Gi GPCR Cell Line
Adenylate Cyclase Activating Polypeptide 1Receptor (ADCYAP1R1)CB-80200-234ACTOne-Gs GPCR Cell Line
Adrenergic receptor beta 1 (ADRB1)CB-80200-272ACTOne-Gs GPCR Cell Line
Amylin 3 ReceptorCB-80200-271ACTOne-Gs GPCR Cell Line
Angiotensin Receptor-like 1CB-80300-267ACTOne-Gi GPCR Cell Line
Arginine Vasopressin 2 Receptor (AVPR2)CB-80200-246ACTOne-Gs GPCR Cell Line
Beta-2 Adrenergic ReceptorCB-80200-253ACTOne-Gs GPCR Cell Line
Calcitonin Receptor (CALCR)CB-80200-258ACTOne-Gs GPCR Cell Line
Calcitonin-like Receptor (CALCRL)CB-80200-251ACTOne-Gs GPCR Cell Line
Cannabinoid Receptor 1 (CB1)CB-80300-205ACTOne-Gi GPCR Cell Line
Cannabinoid Receptor 2 (CB2)CB-80300-225ACTOne-Gi GPCR Cell Line
Chemokine (C-C motif) Receptor 5 (CCR5)CB-80300-213ACTOne-Gi GPCR Cell Line
Chemokine (C-X-C motif) Receptor 4 (CXCR4)CB-80300-265ACTOne-Gi GPCR Cell Line
Corticotropin Releasing Hormone Receptor 1 (CRHR1)CB-80200-249ACTOne-Gs GPCR Cell Line
Corticotropin Releasing Hormone Receptor 2 (CRHR2)CB-80200-233ACTOne-Gs GPCR Cell Line
Dopamine Receptor 1 (DRD1)CB-80200-218ACTOne-Gs GPCR Cell Line
Dopamine Receptor 2 (DRD2)CB-80300-206ACTOne-Gi GPCR Cell Line
Dopamine Receptor 5 (DRD5)CB-80200-222ACTOne-Gs GPCR Cell Line
Follicle Stimulating Hormone Receptor (FSHR)CB-80200-236ACTOne-Gs GPCR Cell Line
Gastric Inhibitor Peptide Receptor (GIPR)CB-80200-221ACTOne-Gs GPCR Cell Line
Glucagon Receptor (GCGR)CB-80200-217ACTOne-Gs GPCR Cell Line.
Glucagon-like Receptor 1 (GLP1R)CB-80200-248ACTOne-Gs GPCR Cell Line
Glucagon-like Receptor 2 (GLP2R)CB-80200-241ACTOne-Gs GPCR Cell Line
Glutamate Receptor, Metabotropic 2CB-80300-262ACTOne-Gi GPCR Cell Line
Glutamate Receptor, Metabotropic 4CB-80300-269ACTOne-Gi GPCR Cell Line
Glutamate Receptor, Metabotropic 7CB-80300-259ACTOne-Gi GPCR Cell Line
Glutamate Receptor, Metabotropic 8CB-80300-239ACTOne-Gi GPCR Cell Line
GPR119CB-80200-274ACTOne-Gs GPCR Cell Line
Luteinizing hormone/Choriogonadotropin receptor (LHCGR)CB-80200-275ACTOne-Gs GPCR Cell Line
Melanin Concentrating Hormone Receptor 1 (MCHR1)CB-80300-214ACTOne-Gi GPCR Cell Line
Melanocortin 1 Receptor (MC1R)CB-80200-257ACTOne-Gs GPCR Cell Line
Melanocortin 3 Receptor (MC3R)CB-80200-243ACTOne-Gs GPCR Cell Line
Melanocortin 4 Receptor (MC4R)CB-80200-211ACTOne-Gs GPCR Cell Line
Melanocortin 5 Receptor (MC5R)CB-80200-215ActOne-Gs GPCR Cell Line
Neuropeptide Y Receptor Y1 (NPY1R)CB-80300-244ACTOne-Gi GPCR Cell Line
Neuropeptide Y Receptor Y2 (NPY2R)CB-80300-245ACTOne-Gi GPCR Cell Line
Neuropeptide Y Receptor Y4 (NPY4R)CB-80300-270ACTOne-Gi GPCR Cell Line
Neuropeptide Y Receptor Y5 (NPY5R)CB-80300-280ACTOne-Gi GPCR Cell Line
Opiate Receptor-like 1 (ORL1)CB-80300-266ACTOne-Gi GPCR Cell Line
Opioid receptor, delta 1CB-80300-279ACTOne-Gi GPCR Cell Line
Opioid receptor, kappa 1CB-80300-230ACTOne-Gi GPCR Cell Line
Opioid receptor, MuCB-80300-268ACTOne-Gi GPCR Cell Line
Parathyroid Hormone Receptor 1 (PTHR1)CB-80200-216ACTOne-Gs GPCR Cell Line
Parathyroid Hormone Receptor 2 (PTHR2)CB-80200-228ACTOne-Gs GPCR Cell Line
Prostaglandin D Receptor 2 (PTGDR2)CB-80200-255ACTOne-Gs GPCR Cell Line
Prostaglandin E Receptor 4 (PTGER4)CB-80200-219ACTOne-Gs GPCR Cell Line
Prostaglandin I2 Receptor (PTGIR)CB-80200-247ACTOne-Gs GPCR Cell Line
PTGER2 (EP2)CB-80200-256ACTOne-Gs GPCR Cell Line
Secretin Receptor (SCTR)CB-80200-235ACTOne-Gs GPCR Cell Line
Serotonin Receptor 1A (HTR1A)CB-80300-277ACTOne-Gi GPCR Cell Line
Serotonin Receptor 1F (HTR1F)CB-80300-276ACTOne-Gi GPCR Cell Line
Serotonin Receptor 4 (HTR4)CB-80200-231ACT)ne-Gs GPCR Cell Line
Serotonin Receptor 6 (HTR6)CB-80200-237ACTOne-Gs GPCR Cell Line
Serotonin Receptor Receptor 7 (HTR7)CB-80200-240ACTOne-Gs GPCR Cell Line
Somatostatin Receptor 5 (SSTR5)CB-80300-207ACTOne-Gi GPCR Cell Line
Sphingolipid G-protein-coupled receptor 1 (EDG1)CB-80300-254ACTOne-Gi GPCR Cell Line
TGR5CB-80200-275ACTOne-Gs GPCR Cell Line
Thyroid Stimulating Hormone Receptor (TSHR)CB-80200-242ACTOne-Gs GPCR Cell Line
Vasoactive Intestinal Peptide Receptor 1 (VIPR1)CB-80200-220ACTOne-Gs GPCR Cell Line.
Vasoactive Intestinal Peptide Receptor 2 (VIPR2)CB-80200-209ACTOne-Gs GPCR Cell Line.
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