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上海起发mol-innov2021价格表

更新时间:2021-06-17      点击次数:3602

 

Molecular Innovations 成立于 1990 年,是研究抗体、蛋白质和 ELISA 试剂盒的主要制造商。我们专注于凝血和溶栓试剂,包括 PAI-1、tPA、尿激酶、凝血因子、玻连蛋白、纤维蛋白原、纤连蛋白、肾素原/肾素、前激肽释放酶、激肽释放酶、白蛋白、纤溶酶原、纤溶酶、抗纤溶酶、凝血酶、抗凝血酶、补体成分和免疫球蛋白. 我们提供全系列的分子生物学试剂,包括 DNA 聚合酶和感受态细胞。现在具有敲除小鼠和突变小鼠动物研究模型,例如 C1 抑制剂敲除(遗传性血管性水肿)、因子 IX 敲除(血友病 B)、前激肽释放酶敲除、点突变和转基因小鼠。我们的客户遍布全球,包括制药和生物技术公司以及主要研究机构。我们提供定制项目和批量报价。所有产品均在我们位于美国密歇根州诺维市的新工厂按照严格的质量控制标准制造。

上海起发mol-innov2021价格表

货号品名规格价格品牌
6XDYEMantisGreen dual-color loading dyes do not inhibit PCR and make monitoring progress easy during electrophoresis. The dyes run outside the range of typical PCR products and therefore do not obscure visualization. The blue dye runs at 4kb and the yellow dye runs under 25bp. Packaged in easy to use individual 1 ml vials.4.0 ml1020mol-innov2021
6X-HISCPAIA patent pending mutant of human PAI-1 containing four mutations that stabilize the activity of PAI-1 has been made available. The N-terminus has been additionally modified with the introduction of a 6-X histidine tag. The tag allows for the immobilization of functionally active PAI-1 onto surfaces such as metal chelate microtiter plates or Ni+2 resins. Many new applications for PAI-1 can be envisioned with this unique reagent.0.5 mg12155mol-innov2021
6X-HISHPAI-AThe N-terminus of this wild type human PAI-1 has been modified with the introduction of a 6-X histidine tag. The tag allows for the immobilization of functionally active PAI-1 onto surfaces such as metal chelate microtiter plates or Ni+2 resins. The purification conditions are gentle and result in an active fraction >99percent pure and >98percent active as determined by SDS PAGE.0.5 mg12155mol-innov2021
6X-HISRPAI-AThe N-terminus of this wild type rat PAI-1 has been modified with the introduction of a 6-X histidine tag. The tag allows for the immobilization of functionally active PAI-1 onto surfaces such as metal chelate microtiter plates or Ni+2 resins. The purification conditions are gentle and result in an active fraction >99percent pure and >60percent active as determined by SDS PAGE.0.5 mg15640mol-innov2021
AHT-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free. This antibody is useful as an isotype control for <i>in vivo</i> experiments.50 mg8330mol-innov2021
AHTIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total Armenian hamster IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react significantly with human, monkey, mouse, rat, dog, pig or rabbit IgG.</b> The concentration of IgG in normal Armenian hamster serum ranges from 5 to 12 mg/ml. The assay measures Armenian hamster IgG in the 2-1,000 ng/ml range. Samples giving Armenian hamster IgG levels above 1,000 ng/ml should be diluted in blocking buffer before use. A 1:100,000 to 1:1,000,000 dilution for serum is suggested for best results. Armenian hamster IgG will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-Armenian hamster IgG primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of Armenian hamster IgG. Color development is directly proportional to the concentration of total IgG in the samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
ANHTTreatment of trypsin with phenylmethylsulfonyl fluoride (PMSF) followed
by a strong base leads to the conversion of Serine 195 to dehydroalanine
at the active site (1). Alpha and beta forms of anhydrotrypsin are
separated by immobilized soybean trypsin inhibitor. The activity of
anhydrotrypsin is greatly reduced compared to native trypsin as
quantified by chromogenic substrate (2). Anhydrotrypsin provided by
our company is the single chain beta-form prepared from Type
XIII bovine trypsin.<br>
References<br>
1. Ako, H. et al. (1972) Biochem Biophys Res Commun. 47:1402-1407.<br>
2. Olson, S.T. et al. (1995) J. Biol. Chem. 270:30007-30017.
0.1 mg5950mol-innov2021
ANHT-IImmobilized anhydrotrypsin selectively adsorbs peptides with Arg, Lys or
AECys (S-aminoethyl cysteine) residues at the C-terminus under weak
acidic conditions (1). Strongly acidic conditions are used to elute the
bound peptides. Peptides with these amino acids at the N-terminus or
internally, as well as free amino acids are not bound. Serine protease
inhibitors such as ecotin and PAI-1 may also be purified on this resin
(2). May be used repeatedly.<br>
References<br>
1. Kumazaki, T. et al. (1987) J. Biochem. (Tokyo) 102:1539-1546.<br>
2. Blouse, G. E. et al. (2003) Biochemistry 42:12260-12272.
1.0 ml9860mol-innov2021
APAIA single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to elastase. PAI-1 is normally a substrate for pancreatic and neutrophil elastase becoming cleaved at the P3 position. This mutant contains a P1 Alanine in place of the wild type Arginine residue resulting in an inhibitor of elastase as potent as alpha-1PI (antitrypsin).0.5 mg12155mol-innov2021
ASBSAPolyclonal antiserum (host rabbit).1.0 ml3825mol-innov2021
ASBSA-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg3825mol-innov2021
ASBSA-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASBSA-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASBSA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASBSA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized BSA.0.1 mg5695mol-innov2021
ASBSA-GF-HT-BIOPolyclonal antibody (host rabbit). Affinity purified by immobilized BSA. Biotin-labeled.0.1 mg6885mol-innov2021
ASCKPG-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg5950mol-innov2021
ASHA2APPolyclonal antiserum (host rabbit).1.0 ml5950mol-innov2021
ASHA2AP-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg5950mol-innov2021
ASHA2AP-GF-BIOBiotin labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASHA2AP-GF-FITCFITC labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASHA2AP-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASHA2AP-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human antiplasmin.0.1 mg6120mol-innov2021
ASHA2AP-GF-HT-BIOBiotin labeled polyclonal antibody (host rabbit). Affinity purified by immobilized human antiplasmin.0.1 mg6120mol-innov2021
ASHATF-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human ATF.0.02 ml7990mol-innov2021
ASHATIIIPolyclonal antiserum (host rabbit) to human antithrombin.1.0 ml5185mol-innov2021
ASHATIII-GFPolyclonal antibody (host rabbit) to human antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASHATIII-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHATIII-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHATIII-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHATIII-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human antithrombin.0.1 mg6035mol-innov2021
ASHCB-ASPolyclonal antibody (host rabbit). Gamma globulin purified by ammonium sulfate fractionation. Reacts to human liver cathepsin B and does not react with human liver cathepsin D, H, and L.1.0 ml4590mol-innov2021
ASHCD-ASPolyclonal antibody (host rabbit). Gamma globulin purified by ammonium sulfate fractionation. Reacts to human liver cathepsin D and does not react with human liver cathepsin B, H, and L.1.0 ml5100mol-innov2021
ASHCG-ASPolyclonal antibody (host rabbit). Gamma globulin purified by ammonium sulfate fractionation. Reacts to human neutrophil cathepsin G. Immunoelectrophoresis: Single arc vs purified human neutrophil cathepsin G.1.0 ml4590mol-innov2021
ASHCH-ASPolyclonal antibody (host rabbit). Gamma globulin purified by ammonium sulfate fractionation. Reacts to human liver cathepsin H and does not react with human liver cathepsin B, D and L.1.0 ml5100mol-innov2021
ASHEC-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Reacts to human erythrocyte catalase.1.0 ml4590mol-innov2021
ASHFBGNPolyclonal antiserum (host rabbit).1.0 ml5950mol-innov2021
ASHFBGN-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg5950mol-innov2021
ASHFBGN-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg7990mol-innov2021
ASHFBGN-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg7990mol-innov2021
ASHFBGN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit).  IgG fraction purified by immobilized Protein A.1.0 mg7990mol-innov2021
ASHFBGN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human fibrinogen.0.1 mg7990mol-innov2021
ASHFBNPolyclonal antiserum (host rabbit) to human fibronectin.1.0 ml5185mol-innov2021
ASHFBN-GFPolyclonal antibody (host rabbit) to human fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASHFBN-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to human fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHFBN-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHFBN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHFBN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human fibronectin.0.1 mg6035mol-innov2021
ASHFVIIPolyclonal antiserum (host rabbit) to human Factor VII.1.0 ml5695mol-innov2021
ASHFVII-GFPolyclonal antibody (host rabbit) to human Factor VII. IgG fraction purified by immobilized Protein A.1.0 mg5695mol-innov2021
ASHFVII-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to human Factor VII. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFVII-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human Factor VII. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFVII-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human Factor VII. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFVII-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human factor VII.0.1 mg6630mol-innov2021
ASHFXPolyclonal antiserum (host rabbit) to human factor X.1.0 ml5695mol-innov2021
ASHFX-GFPolyclonal antibody (host rabbit) to human factor X. IgG fraction purified by immobilized Protein A.1.0 mg5695mol-innov2021
ASHFX-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to human factor X. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFX-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human factor X. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFX-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human factor X. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHFX-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human factor X.0.1 mg6630mol-innov2021
ASHMPO-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Reacts to human neutrophil myeloperoxidase.1.0 ml5100mol-innov2021
ASHNE-ASPolyclonal antibody (host rabbit). Gamma globulin purified by ammonium sulfate fractionation. Reacts to human neutrophil elastase, and does not react to human neutrophil cathepsin G, myeloperoxidase, or proteinase 3.1.0 ml5100mol-innov2021
ASHPAIPolyclonal antiserum (host rabbit).1.0 ml6290mol-innov2021
ASHPAI-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6290mol-innov2021
ASHPAI-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPAI-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPAI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPAI-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human PAI-1.0.1 mg7990mol-innov2021
ASHPRENPolyclonal antiserum (host rabbit) to human prorenin.1.0 ml5695mol-innov2021
ASHPREN-GFPolyclonal antibody (host rabbit) to human prorenin. IgG fraction purified by immobilized Protein A.1.0 mg5695mol-innov2021
ASHPREN-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to human renin. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPREN-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human prorenin. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPREN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human prorenin. IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHPREN-GF-HTAffinity purified polyclonal antibody (host rabbit) to human renin. IgG fraction purified by immobilized Prorenin.0.1 mg6630mol-innov2021
ASHPTPolyclonal antiserum (host rabbit) to human prothrombin and thrombin.1.0 ml5185mol-innov2021
ASHPT-GFPolyclonal antibody (host rabbit) to human prothrombin and thrombin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASHPT-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to human prothrombin and thrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHPT-GF-FITCFITC labeled polyclonal antibody (host rabbit) to human prothrombin and thrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHPT-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to human prothrombin and thrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASHPT-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human prothrombin.0.1 mg6035mol-innov2021
ASHTPAPolyclonal antiserum (host rabbit).1.0 ml6290mol-innov2021
ASHTPA-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6290mol-innov2021
ASHTPA-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHTPA-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHTPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6630mol-innov2021
ASHTPA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human tPA.0.1 mg7310mol-innov2021
ASHTRYP-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Reacts to human pancreatic trypsin.1.0 ml5440mol-innov2021
ASHUPAPolyclonal antiserum (host rabbit).1.0 ml6290mol-innov2021
ASHUPA-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6290mol-innov2021
ASHUPA-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6545mol-innov2021
ASHUPA-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6545mol-innov2021
ASHUPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6545mol-innov2021
ASHUPA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human uPA.0.1 mg7990mol-innov2021
ASHVNPolyclonal antiserum (host rabbit). Cross reacts with bovine vitronectin.1.0 ml5950mol-innov2021
ASHVN-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with bovine vitronectin.1.0 mg5950mol-innov2021
ASHVN-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with bovine vitronectin.1.0 mg7990mol-innov2021
ASHVN-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with bovine vitronectin.1.0 mg7990mol-innov2021
ASHVN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with bovine vitronectin.1.0 mg7990mol-innov2021
ASHVN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized human vitronectin.0.1 mg7990mol-innov2021
ASMA2APPolyclonal antiserum (host rabbit).1.0 ml5950mol-innov2021
ASMA2AP-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg5950mol-innov2021
ASMA2AP-GF-BIOBiotin labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7310mol-innov2021
ASMA2AP-GF-FITCFITC labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7310mol-innov2021
ASMA2AP-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7310mol-innov2021
ASMA2AP-GF-HTPolyclonal antibody (host rabbit). 
Affinity purified by immoblized mouse antiplasmin.
0.1 mg7310mol-innov2021
ASMA2AP-GF-HT-BIOPolyclonal antibody (host rabbit). 
Affinity purified by immoblized mouse antiplasmin, then biotin-labeled.
0.1 mg12155mol-innov2021
ASMATIIIPolyclonal antiserum (host rabbit) to mouse antithrombin.1.0 ml5185mol-innov2021
ASMATIII-GFPolyclonal antibody (host rabbit) to mouse antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASMATIII-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMATIII-GF-FITCFITC labeled polyclonal antibody (host rabbit) to mouse antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMATIII-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to mouse antithrombin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMATIII-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse antithrombin.0.1 mg6035mol-innov2021
ASMATIII-GF-HT-BIOBiotin labeled polyclonal antibody (host rabbit). Affinity purified by immobilized mouse antithrombin.0.1 mg6885mol-innov2021
ASMFBGNPolyclonal antiserum (host rabbit). Cross reacts with rat fibrinogen.1.0 ml5185mol-innov2021
ASMFBGN-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with rat fibrinogen.1.0 mg5185mol-innov2021
ASMFBGN-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with rat fibrinogen.1.0 mg6885mol-innov2021
ASMFBGN-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with rat fibrinogen.1.0 mg6885mol-innov2021
ASMFBGN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Cross reacts with rat fibrinogen.1.0 mg6885mol-innov2021
ASMFBGN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse fibrinogen. Cross reacts with rat fibrinogen.0.1 mg6885mol-innov2021
ASMFBNPolyclonal antiserum (host rabbit) to mouse fibronectin.1.0 ml5185mol-innov2021
ASMFBN-GFPolyclonal antibody (host rabbit) to mouse fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASMFBN-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMFBN-GF-FITCFITC labeled polyclonal antibody (host rabbit) to mouse fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMFBN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to mouse fibronectin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMFBN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse fibronectin.0.1 mg6035mol-innov2021
ASMFXIIPolyclonal antiserum (host rabbit) to mouse factor XII.1.0 ml7905mol-innov2021
ASMFXII-GFPolyclonal antibody (host rabbit) to mouse factor XII. IgG fraction purified by immobilized Protein A.1.0 mg7905mol-innov2021
ASMFXII-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse factor XII. IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMFXII-GF-FITCFITC labeled polyclonal antibody (host rabbit) to mouse factor XII. IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMFXII-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to mouse factor XII. IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMFXII-GF-HTPolyclonal antibody (host rabbit) to mouse factor XII. Affinity purified by immobilized mouse factor XII.0.1 mg6035mol-innov2021
ASMFXII-GF-HT-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse factor XII. Affinity purified by immobilized mouse factor XII.0.1 mg6885mol-innov2021
ASMPAIPolyclonal antiserum (host rabbit).1.0 ml6545mol-innov2021
ASMPAI-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6545mol-innov2021
ASMPAI-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6885mol-innov2021
ASMPAI-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6885mol-innov2021
ASMPAI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6885mol-innov2021
ASMPAI-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse PAI-1.0.1 mg7990mol-innov2021
ASMPLGPolyclonal antiserum (host rabbit).1.0 ml5950mol-innov2021
ASMPLG-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Suitable for: ELISA, IHC, WB1.0 mg5950mol-innov2021
ASMPLG-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6800mol-innov2021
ASMPLG-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6800mol-innov2021
ASMPLG-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6800mol-innov2021
ASMPLG-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse plasminogen.0.1 mg6800mol-innov2021
ASMPRENPolyclonal antiserum (host rabbit) to mouse prorenin.1.0 ml5185mol-innov2021
ASMPREN-GFPolyclonal antibody (host rabbit) to mouse prorenin. IgG fraction purified by immobilized Protein A.1.0 mg5185mol-innov2021
ASMPREN-GF-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse prorenin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMPREN-GF-FITCFITC labeled polyclonal antibody (host rabbit) to mouse prorenin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMPREN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit) to mouse prorenin. IgG fraction purified by immobilized Protein A.1.0 mg6035mol-innov2021
ASMPREN-GF-HTPolyclonal antibody (host rabbit) to mouse prorenin. Affinity purified IgG fraction.0.1 mg6885mol-innov2021
ASMPREN-GF-HT-BIOBiotin labeled polyclonal antibody (host rabbit) to mouse prorenin. Affinity purified IgG fraction.0.1 mg6885mol-innov2021
ASMTPAPolyclonal antiserum (host rabbit).1.0 ml7990mol-innov2021
ASMTPA-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A. Suitable for: ELISA, WB, IHC1.0 mg7990mol-innov2021
ASMTPA-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMTPA-GF-FITCFluorescein labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMTPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMTPA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse tPA.0.1 mg5950mol-innov2021
ASMUPAPolyclonal antiserum (host rabbit).1.0 ml5185mol-innov2021
ASMUPA-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg5185mol-innov2021
ASMUPA-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMUPA-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMUPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
ASMUPA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized mouse uPA.0.1 mg8670mol-innov2021
ASMVNPolyclonal antiserum (host rabbit).1.0 ml5950mol-innov2021
ASMVN-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg5950mol-innov2021
ASMVN-GF-BIOBiotin labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASMVN-GF-FITCFITC labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASMVN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
ASMVN-GF-HTPolyclonal antibody (host rabbit). 
Affinity purified by immobilized mouse vitronectin.
0.1 mg7990mol-innov2021
ASPFBGNPolyclonal antiserum (host rabbit).1.0 ml3825mol-innov2021
ASPFBGN-GFPolyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg3825mol-innov2021
ASPFBGN-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASPFBGN-GF-FITCFITC labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASPFBGN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg4760mol-innov2021
ASPFBGN-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized porcine fibrinogen.0.1 mg3825mol-innov2021
ASRPAIPolyclonal antiserum (host rabbit).1.0 ml6545mol-innov2021
ASRPAI-GFPolyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6545mol-innov2021
ASRPAI-GF-BIOBiotin labeled polyclonal antibody (host rabbit). IgG fraction purified by immobilized Protein A.1.0 mg6885mol-innov2021
ASRPAI-GF-FITCFITC labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6885mol-innov2021
ASRPAI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host rabbit).
IgG fraction purified by immobilized Protein A.
1.0 mg6885mol-innov2021
ASRPAI-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized rat PAI-1.0.1 mg7310mol-innov2021
ASRPLM-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized rat plasmin.0.1 mg6800mol-innov2021
ASRUPA-GF-HTPolyclonal antibody (host rabbit). Affinity purified by immobilized rat uPA.0.1 mg8670mol-innov2021
AVI-HRPHorseradish peroxidase conjugated purified avidin from chicken egg white. Specific for biotin, biotinylated proteins, or biotinylated antibodies. Recommended starting dilution for ELISA is 1:1,000 but proper working dilution must be optimized by the end user.
<br>Please be aware that our minimum order is $50.
0.01 ml510mol-innov2021
AVI-PLATE96 well plate with 8 removable strips coated with Avidin at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of biotin-conjugated proteins and antibodies. Binding performance is characterized with biotinylated rabbit IgG followed by detection with HRP labeled secondary antibody.<br><br>
<b>Advantages of Avidin Plates from Molecular Innovations:</b><br>
Senstitive - detect down to 0.1 ng/ml of biotinylated IgG<br>
Specific - low background with high signal to noise ratio<br>
High Capacity - binds >100 ng/ml of biotinylated IgG<br>
Robust - broad dynamic range<br>
Convenient - Ready to use plates are supplied pre-blocked to save time<br>
Accurate - inter-assay CV is less than or equal to 3.47percent up to 100 ng/ml of biotinylated IgG
5 plates2210mol-innov2021
BAP-IImmobilized bovine aprotinin, also known as trasylol or iniprol, is a reversible inhibitor of a range of serine proteases including trypsin, chymotrypsin, plasmin, and kallikrein. Binding occurs at a range of physiological conditions with elution of target proteases at very high or very low pH values. The agarose resin is easily removed by centrifugation or filtration and is reusable.<br><br> 
<u>Immobilized Aprotinin Digestion Protocol</u><br> 
1. Make a digestion buffer consisting of 0.1M Tris-HCl, 0.15M NaCl, pH 7.4 (or other suitable physiological buffer such as PBS).<br> 
2. Wash desired amount of immobilized aprotinin with at least three column volumes of binding buffer. 
3. Resuspend the washed immobilized aprotinin gel in binding buffer then add the resin to your protein sample. 
4. Incubate mixture with gentle agitation for 30 minutes at room temperature. 
5. Separate the immobilized aprotinin from the binding reaction by centrifugation or gravity filtration. Retain supernatant as your serine protease depleted protein sample. 
6. To elute bound active enzymes and regenerate immobilized aprotinin gel, thoroughly wash the resin with binding buffer then elute with 0.1M Glycine, 0.1M NaCl, pH 2.9. Collect elution into 1M Tris-HCl, pH 7.4 to restore neutral pH if desired.
1.0 ml3485mol-innov2021
BCT-IImmobilized bovine chymotrypsin is ideal for digestions of proteins and peptides. Chymotrypsin is a protease that cleaves peptide bonds at Trp, Tyr, Phe, Leu and Met. Chymotrypsin protease is generally specific for hydrophobic residues and is often used to provide complementary sequence coverage when compared to tryptic digested samples.<br><br> 
<u>Immobilized Chymotrypsin Digestion Protocol</u><br> 
1. Make a digestion buffer consisting of 0.08M Tris-HCl, 0.1M Calcium Chloride, pH 7.8 (or other suitable buffer 
such as 0.1M Ammonium Bicarbonate, 0.01M Calcium Chloride, pH 8.0).<br> 
2. Dissolve 1 mg of your protein sample in 0.2ml digestion buffer.<br> 
3. Wash 0.2-0.3ml of immobilized chymotrypsin with 3x0.5ml of digestion buffer. Separate the gel from 
the buffer after each wash by centrifugation or by column. Discard buffer after each wash.<br> 
4. Resuspend the washed immobilized chymotrypsin gel in ~0.2ml of digestion buffer then add the resin to your protein sample.<br> 
5. Incubate mixture in a shaking water bath for 2-18 hours at 37C with rapid agitation.<br> 
6. Separate the immobilized chymotrypsin gel from the digestion mixture as noted in step 3. Retain supernatant 
as your chymotrypsin-digested protein sample.<br><br> 
<u>Note</u>: Optimization of immobilized chymotrypsin protocol is required for specific applications. Recommended reaction conditions are pH 7.5 to 9.0 at 37C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature. For example, a typical digestion of 4 hours to overnight can be 
achieved using a ratio of 1:25 enzyme to protein substrate, while it is recommended to use 1:10 enzyme to protein substrate for accelerated chymotrypsin digestion (30-60 minutes).
5.0 ml3910mol-innov2021
BFBGNPrepared from fresh bovine plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.25 mg2805mol-innov2021
BFBGN-FITCBovine fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh bovine plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.10 mg2805mol-innov2021
BFXBovine factor X is isolated from fresh frozen bovine plasma. Purity is determined by SDS-PAGE analysis and activity is measured in a Factor X clotting assay.0.1 mg5525mol-innov2021
BFXAFactor Xa is prepared by activating purified Factor X with the Factor X activator isolated from Russell's viper venom. Cleavage occurs at the Arg51-Ile52 bond and releases an activation peptide. Factor Xa is purified from the activation mixture by chromatography over benzamidine-Sepharose. Purity is determined by SDS-PAGE analysis and activity is measured in a Factor Xa clotting assay and/or chromogenic substrate assay.0.1 mg5525mol-innov2021
BIOTHROMKTEach kit contains 10 units of biotinylated thrombin for cleavage of up to 10 mg recombinant protein along with 2 ml of 10X thrombin cleavage buffer and 10 ug of cleavage control protein. Cleavage control protein is converted from a single 67 kDa band to two bands of 39 kDa and 28 kDa following thrombin cleavage. Store all components at -20 C.<br> 
Biotinylated thrombin is useful for cleavage of proteins and peptides at the enzyme recognition sequence Leu-Val-Pro-Arg-||-Gly-Ser. Biotinylated thrombin is then easily removed from the reaction with immobilized avidin agarose resin. This preparation is &gt;95% pure on SDS-PAGE and is tested for activity using thrombin chromogenic substrate and cleavage control protein.<br><br> 
Biotinylated Thrombin Cleavage Protocol</u><br> 
1. Combine 100ul of 10X cleavage buffer, 1mg of target protein, and 1U of biotinylated thrombin with ultrapure water to a total volume of 1ml.<br> 
2. Monitor cleavage with a parallel reaction of cleavage control protein in the same buffer as the target protein.<br> 
3. Incubate overnight at room temperature.<br> 
4. Remove biotinylated thrombin with immobilized avidin or streptavidin agarose resin according to the manufacturer's recommended directions. This resin cannot be reused.<br> 
5. Residual uncleaved fusion tagged protein along with cleaved purification tag in the reaction can usually be removed by reapplying to the original purification resin after reequilibration in binding buffer.<br><br> 
<u>Notes</u>: Optimization of biotinylated thrombin protocol is required for specific applications. Recommended reaction conditions are pH 7.0 to 9.0 at 20C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature. For example, addition of 2U of biotinylated thrombin and incubation at 37C will result in accelerated thrombin digestion (30-60 minutes).<br> 
Cleavage at sites similar to the enzyme recognition sequence can be limited by decreasing enzyme to protein substrate ratio and incubation temperature. A pilot scale digestion is recommended for optimization of the reaction by removing samples at 2, 4, 8, and 16 hours and analyzing by SDS-PAGE.<br> 
Biotinylated thrombin can be diluted in TBS or PBS.
1 kit5100mol-innov2021
BL21BL21(DE3) strain chemically competent cells from Molecular Innovations are an all purpose reagent for T7 promoter driven IPTG inducible E. coli protein expression. For greater transformation efficiencies heat shock at 37C for 1 minute before plating, or heat shock at 42C for 30 seconds then add SOC media and shake at 225 rpm at 37C for 1 hour before plating. Conveniently supplied as a pack of 5 single use 0.2 ml aliquots. 
 
 
Other strains of competent cells available upon request Click here to request a strain.
1.0 ml1700mol-innov2021
BPLGPrepared from fresh bovine plasma by immobilized lysine chromatography.1.0 mg3060mol-innov2021
BPLMPrepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.<br> 
Partial cleavage of bovine plasmin between kringles 3 & 4 occurs upon activation, producing a low molecular weight band. This midiplasmin is 100 percent active (Christensen et al. Biochem J. 305 (Pt 1):97-102, 1995).
1.0 mg4080mol-innov2021
BSA12C8D4Monoclonal antibody (host mouse).
IgG fraction purified by immobilized Protein A. Isotype IgG1Kappa.
1.0 mg3825mol-innov2021
BSA9E2C2Monoclonal antibody (host mouse).
IgG fraction purified by immobilized Protein A. Isotype IgG1Kappa.
1.0 mg3825mol-innov2021
BTAQTaqCurate is an optimized blend of TaqRobat native Taq and PyFi high fidelity DNA polymerases. TaqCurate combines the robust amplification of Taq with 3&#39;-5&#39; exonuclease proofreading capability for a reagent that is great for routine PCR and amplification of longer and more difficult products. The fidelity of TaqCurate is over two-fold greater than Taq alone. TaqCurate will produce products with both blunt ends and dA overhangs. Suitable for Standard Endpoint PCR, Colony PCR, Genotyping, TA Cloning, and Mutagenesis of GC-Rich DNA templates up to 10kb. Includes 10X reaction buffer.200 units2040mol-innov2021
BTHROM-ABovine alpha-thrombin is prepared from purified prothrombin by activation with coastal taipan venom followed by affinity chromatography. Purity is verified by SDS-PAGE analysis and specific activity in NIH thrombin units is determined by chromogenic substrate.1.0 mg4250mol-innov2021
BTHROM-IImmobilized bovine thrombin is ideal for cleavage of recombinant fusion proteins with an Leu-Val-Pro-Arg/Gly-Ser thrombin recognition sequence. The resin is easily removed by centrifugation or filtration following the reaction. Immobilized bovine thrombin is highly specific, useful in a wide range of reaction buffers and temperatures, and reusable.<br><br> 
<u>Immobilized Thrombin Digestion Protocol</u><br> 
1. Make a digestion buffer consisting of 0.05M Tris-HCl, 0.01M CaCl2, pH 8.0.<br> 
2. Dissolve 1 mg of your protein sample in 1 ml digestion buffer.<br> 
3. Wash 0.05-0.1ml of immobilized thrombin with 3x0.5ml of digestion buffer. Separate the gel from the buffer after each wash by centrifugation or by column. Discard buffer after each wash.<br> 
4. Resuspend the washed immobilized thrombin gel in ~0.2ml of digestion buffer then add the resin to your protein sample.<br> 
5. Incubate mixture in a shaking water bath for 1-2 hours at 37C, or overnight at 4C, with rapid agitation.<br> 
6. Separate the immobilized thrombin gel from the digestion mixture as noted in step 3. Retain supernatant as your thrombin-digested protein sample.<br><br> 
<u>Note</u>: Optimization of immobilized thrombin protocol is required for specific applications. Recommended reaction conditions are pH 7.0 to 9.0 at 37C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature. For example, a typical digestion of 4 hours to overnight can be achieved using a ratio of 1:25 enzyme to protein substrate, while it is recommended to use 1:10 enzyme to protein substrate for accelerated thrombin digestion (30-60 minutes).
1.0 ml3485mol-innov2021
BTRYP-IImmobilized bovine trypsin is ideal for digestions of proteins and peptides. Trypsin is a protease that cleaves peptide bonds at Arg and Lys. Trypsin protease is TPCK treated to remove chymotryptic activity before immobilization. Trypsin can be used to provide complementary sequence coverage when compared to chymotryptic digested samples.<br><br> 
<u>Immobilized Trypsin Digestion Protocol</u><br> 
1. Make a digestion buffer consisting of 0.1M Ammonium Bicarbonate, pH 8.0 (or other suitable buffer such as 0.1M Triethylamine Acetate, pH 8.0).<br> 
2. Dissolve 1 mg of your protein sample in 0.5ml digestion buffer.<br> 
3. Wash 0.15-0.3ml of immobilized trypsin with 3x0.5ml of digestion buffer. Separate the gel from the buffer after each wash by centrifugation or by column. Discard buffer after each wash.<br> 
4. Resuspend the washed immobilized trypsin gel in ~0.2ml of digestion buffer then add the resin to your protein sample.<br> 
5. Incubate mixture in a shaking water bath for 2-18 hours at 37C with rapid agitation.<br> 
6. Separate the immobilized trypsin gel from the digestion mixture as noted in step 3. Retain supernatant as your trypsin-digested protein sample.<br><br> 
<u>Note</u>: Optimization of immobilized trypsin protocol is required for specific applications. Recommended reaction conditions are pH 7.5 to 9.0 at 37C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature. For example, a typical digestion of 4 hours to overnight can be achieved using a ratio of 1:25 enzyme to protein substrate, while it is recommended to use 1:10 enzyme to protein substrate for accelerated trypsin digestion (30-60 minutes).
5.0 ml3910mol-innov2021
BV-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free.50 mg1105mol-innov2021
BVNPrepared from fresh bovine plasma using urea as a denaturant.0.1 mg3995mol-innov2021
C1INH7D10Mouse monoclonal antibody to mouse C1 Inhibitor produced in a C1 Inhibitor knockout mouse. C1 Inhibitor (also known as plasma protease C1 inhibitor, C1 esterase inhibitor, C1-inhibiting factor, C1-INH, and C1INA) is a single chain glycosylated serine protease inhibitor (serpin) which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. IgG fraction purified by immobilized Protein A/G. Detects C1 Inhibitor under non-reducing and reducing conditions. Clone 7D10-F8, isotype IgG3 kappa.0.1 mg6715mol-innov2021
CCL17C-C motif chemokine 17 (CCL17) is a 71 amino acid Cys-Cys chemokine that plays important roles in T cell development in the thymus as well as in trafficking and activation of mature T cells. It is also known as thymus and activation regulated chemokine (TARC). CCL17 is a ligand for the G protein coupled receptors CCR4 and CCR8, and induces chemotactic migration of T lymphocytes, but not monocytes or granulocytes. CCL17 is expressed at high levels in the thymus and at low levels in the lung, colon and small intestine. CCL17 is induced by phytohemagglutinin in the peripheral blood mononuclear cells and by cytokines in monocytes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells. Recombinant human CCL17 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CCR4 activity verified by chemotaxis using HH cells. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg5865mol-innov2021
CCL2C-C motif chemokine 2 (CCL2) is a 76 amino acid Cys-Cys chemokine that has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It is also known as monocyte chemoattractant protein 1 (MCP1), monocyte chemotactic and activating factor (MCAF), and small inducible cytokine A2. CCL2 is a ligand for the G protein coupled receptors CCR2 and CCR4, and induces chemotactic migration of monocytes, activated T cells, basophils, NK cells and dendritic cells, but not neutrophils or eosinophils. CCL2 can augment monocyte anti-tumor activity and may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells. Recombinant human CCL2 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CCR2 activity verified by intracellular calcium flux using THP1 cells as described by Veldkamp et al, Science Signaling 2008. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CCL20C-C motif chemokine 20 (CCL20) is a 70 amino acid Cys-Cys chemokine that can repress proliferation of myeloid progenitors. It is also known as liver activation regulated chemokine (LARC) and macrophage inflammatory protein-3 (MIP3A). CCL20 is a ligand for the G protein coupled receptor CCR6, and is strongly chemotactic for lymphocytes, weakly chemotactic for neutrophils, but does not attract monocytes. CCL20 induces chemotactic migration in a wide range of CCR6-expressing cells including immature dendritic cells, effector/memory T-cells and B-cells. CCL20 may be involved in the formation and function of mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards the epithelial cells surrounding these tissues. CCL20 is expressed at high levels in the liver, lymph nodes, appendix, peripheral blood lymphocytes and fetal lung and at low levels in the thymus, prostate, testis, small intestine and colon. CCL20 is induced by lipopolysaccharides, TNF and IFNG/IFN-gamma and repressed by IL-10. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells. Recombinant human CCL20 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CCR6 activity verified by intracellular calcium flux using transfected Jurkat cells. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CCL21C-C motif chemokine 21 (CCL21) is a 111 amino acid Cys-Cys chemokine that inhibits hemopoiesis and stimulates chemotaxis. It is also known as secondary lymphoid-tissue chemokine (SLC) and 6Ckine because it contains 6 conserved cysteines, in contrast to the 4 that are more typical of CC chemokines. CCL21 is a ligand for the G protein coupled receptor CCR7, and is chemotactic for thymocytes and activated T-cells, but not for B cells, macrophages, or neutrophils. It also binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin to ACKR4. CCL21 recruits normal immune cells and metastasizing tumor cells to secondary lymphoid organs and shows preferential activity towards naive T-cells. CCL21 is expressed at high levels in the lymph nodes, spleen and appendix, intermediate levels in the small intestine, thyroid gland and trachea, and at low levels in the thymus, bone marrow, liver, and pancreas. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC chemokines are chemotactic cytokines characterized by two adjacent cysteines that induce directed chemotaxis in nearby responsive cells. Recombinant human CCL21 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CCR7 activity verified by chemotaxis using T2 cells. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CDNAReality Reverse Transcriptase is a modified version of M-MLV reverse transcriptase with increased thermal stability and deactivated RNase H activity. In combination with optimized buffers and reagents, Reality Reverse Transcriptase synthesizes complementary DNA from single-stranded RNA or DNA templates. The enzyme is sensitive, specific and capable of synthesizing highly-structured and long cDNA fragments. The cDNA produced is appropriate for both PCR and qPCR analysis. Reality offers higher cDNA yields than some leading competitors with highly sensitive efficient synthesis from low-abundance RNA transcripts. Suitable for cDNA Synthesis of products from 100bp up to 10kb. The kit contains Reality Reverse Transcriptase (200U/&micro;l), 5X buffer, dNTP mix (10mM), DTT solution (100mM), RNase inhibitor (40U/&micro;l), Oligo dT 20mer primer (100&micro;M), random hexamers (100&micro;M), positive control RNA (10ng/&micro;l), and RNase-free water.<br><br> 
<b>Protocol:</b> The following setup is recommended for a 20&micro;l reaction.<br><br> 
<b>Step 1A:</b> cDNA synthesis without denaturation<br> 
<table border=1px padding=5px width="80%" style=font-size:12px>  
<tr><th width="20%">Component</th><th width="20%">Stock Concentration</th><th width="50%">Final Concentration</th><th width="10%">Volume</th</tr> 
<tr><td>RNA Template</td><td>-</td><td>Total RNA: 10pg-5&micro;g or mRNA: 10pg-500ng</td><td>X &micro;l </td></tr>  
<tr><td>Primer</td><td>100&micro;M</td><td>Gene Specific Primer: 10-20pmol (50-100ng)<br>Oligo dT or random hexamer: 50pmol</td><td>0.1-0.2&micro;l<br>0.5&micro;l<br></td></tr>  
<tr><td>dNTP Mix</td><td>10mM</td><td>500&micro;M</td><td>1&micro;l</td></tr>  
<tr><td>DTT Solution</td><td>100mM</td><td>5mM</td><td>1&micro;l</td></tr>  
<tr><td>RNase Inhibitor</td><td>40U/&micro;l</td><td>40U</td><td>1&micro;l</td></tr>  
<tr><td>Reality Reverse Transcriptase</td><td>200U/&micro;l</td><td>100U</td><td>0.5&micro;l</td></tr>  
<tr><td>5X Buffer</td><td>5X</td><td>1X</td><td>4&micro;l</td></tr> 
<tr><td>RNase Free Water</td><td>-</td><td>-</td><td>QS to 20&micro;l</td></tr> 
</table><br> 
<b>Step 1B (Optional):</b> cDNA synthesis with denaturation<br> 
First, prepare the Template/Primer mix using the table below and incubate 5min at 65-70&deg;C.<br> 
<table border=1px padding=5px width="80%" style=font-size:12px style=text-align:center>  
<tr><th width="20%">Component</th><th width="20%">Stock Concentration</th><th width="50%">Final Concentration</th><th width="10%">Volume</th</tr> 
<tr><td>RNA Template</td><td>-</td><td>Total RNA: 10pg-5&micro;g or mRNA: 10pg-500ng</td><td>X &micro;l </td></tr>  
<tr><td>Primer</td><td>100&micro;M</td><td> Gene Specific Primer: 10-20pmol (50-100ng)<br> Oligo dT or random hexamer: 50pmol</td><td>0.1-0.2&micro;l<br>0.5&micro;l<br></td></tr>  
<tr><td>RNase Free Water</td><td>-</td><td>-</td><td>QS to 10&micro;l</td></tr> 
</table><br> 
Second, prepare the Reaction mix using the table below.<br> 
<table border=1px padding=5px width="80%" style=font-size:12px style=text-align:center>  
<tr><th width="20%">Component</th><th width="20%">Stock Concentration</th><th width="50%">Final Concentration</th><th width="10%">Volume</th</tr> 
<tr><td>dNTP Mix</td><td>10mM</td><td>500&micro;M</td><td>1&micro;l</td></tr>  
<tr><td>DTT Solution*</td><td>100mM</td><td>5mM</td><td>1&micro;l</td></tr>  
<tr><td>RNase Inhibitor**</td><td>40U/&micro;l</td><td>40U</td><td>1&micro;l</td></tr>  
<tr><td>Reality Reverse Transcriptase***</td><td>200U/&micro;l</td><td>100U</td><td>0.5&micro;l</td></tr>  
<tr><td>5X Buffer</td><td>5X</td><td>1X</td><td>4&micro;l</td></tr> 
<tr><td>RNase Free Water</td><td>-</td><td>-</td><td>QS to 10&micro;l</td></tr> 
</table> 
<p style=font-size:10px>*Adding up to 5mM DTT may increase the yield and is recommended for individual optimization.<br> **An additional 20-40 Units of RNase inhibitor per reaction is recommended when using low amounts of starting RNA.<br> 
***Increased transcription levels may be achieved by increasing the amount of enzyme to 200 Units.</p> 
Third, add 10&micro;l of Reaction mix to 10&micro;l of Template/Primer mix and pipette gently up and down on ice.<br><br> 
<b>Step 2:</b> Incubation<br> 
Gene Specific Primers: 30-60min at 50&deg;C.<br> 
Oligo dT or random hexamer: 10min at 42&deg;C followed by 30-60min at 50&deg;C.<br><br> 
<b>Step 3 (Optional):</b> Heat inactivation<br> 
Heat the mixture for 10min at 70&deg;C to inactivate Reverse Transcriptase.<br><br> 
<b>Step 4 (Optional):</b> RNA removal<br> 
Add 2 Units of DNase-free RNase and incubate for 20min at 37&deg;C. The cDNA can now be used as a template in PCR and should be stored at -20&deg;C.
100 rxn7565mol-innov2021
CKPGPrepared from fresh chicken plasma by immobilized lysine chromatography.1.0 mg4080mol-innov2021
CKPLA-SER-PGPrepared from frozen chicken serum.10 ml4420mol-innov2021
CKPLMPrepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg6035mol-innov2021
COVID-GFSARS-CoV-2 is the novel coronavirus that causes CoronaVirus Disease 2019 (COVID-19). This IgG fraction is purified by immobilized Protein A from pooled sera collected from convalescent COVID-19 patients. Serum was collected at least two weeks post symptom development from patients with positive COVID-19 PCR and serology tests. This antibody preparation is strongly positive in the Molecular Innovations SARS-CoV-2 IgG Seroconversion ELISA Kit and can be useful as a positive control or calibrator in a variety of serological assays. Add PBS to desired volume, aliquot and freeze unused portion.0.05 mg6715mol-innov2021
COVID-GF-HTSARS-CoV-2 is the novel coronavirus that causes CoronaVirus Disease 2019 (COVID-19). This antibody preparation is affinity purified by immobilized recombinant receptor-binding domain (RBD) of the SARS-CoV-2 spike protein from Protein A/G purified IgG from pooled sera collected from convalescent COVID-19 patients. Serum was collected at least two weeks post symptom development from patients with positive COVID-19 PCR and serology tests. This antibody preparation is strongly positive in the Molecular Innovations SARS-CoV-2 IgG Seroconversion ELISA Kit and is useful as a positive control or calibrator in a variety of serological assays. Add deionized water to original volume, aliquot and freeze unused portion.0.01 ml5015mol-innov2021
CPAIThe human form of PAI-1 contains the following four mutations: K154T, Q319L, M354I and N150H. These mutations combine to confer great stability to the otherwise labile molecule essentially locking in into the active conformation. It is an ideal choice for in vivo studies.0.5 mg12155mol-innov2021
CPAI-EDThe human form of PAI-1 contains the following four mutations: K154T, Q319L, M354I and N150H. These mutations combine to confer great stability to the otherwise labile molecule essentially locking in into the active conformation. It is an ideal choice for in vivo and cell culture studies. This preparation is purified to lower levels of endotoxin (<0.01 EU/ug) and does not contain animal carrier proteins or sodium azide. It is lyophilized and fully active.  Add sterile endotoxin free deionized water to original volume or PAI-1 storage buffer (0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6) to desired volume. Aliquot and freeze unused portion.0.1 mg10200mol-innov2021
CPAI-P1NBDMutagenesis of the P1' methionine residue (Met347) at the P1-P1' scissile bond of human PAI-1 stable mutant (K154T, Q319L, M354I and N150H) to cysteine followed by incorporation of NBD has produced a reporter PAI-1 with extended half life. The properties of this interesting new reagent have not been fully characterized.0.5 mg12155mol-innov2021
CPAI-P9NBDMutagenesis of the P9 serine residue (Ser338) on the reactive center loop of human PAI-1 stable mutant (K154T, Q319L, M354I and N150H) to cysteine followed by incorporation of NBD has produced a reporter PAI-1 with extended half life. The properties of this interesting new reagent have not been fully characterized.0.5 mg12155mol-innov2021
CPAI-Q123KThe Q123K point mutation on the human PAI-1 stable mutant background (K154T, Q319L, M354I and N150H) results in PAI-1 with a greatly extended half life and ten-fold reduced binding to the important ligand vitronectin.<br>
References<br>
Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal. Jensen JK, Durand MK, Skeldal S, Dupont DM, Bødker JS, Wind T, Andreasen PA. FEBS Lett. 2004 Jan 2;556(1-3):175-9.<br>
Conservation of Critical Functional Domains in Murine Plasminogen Activator Inhibitor-1. Zhi Xu, Rashna D. Balsara, Natalia V. Gorlatova, Daniel A. Lawrence, Francis J. Castellino, and Victoria A. Ploplis. J. Biol. Chem., Apr 2004; 279:17914-20.
0.5 mg12155mol-innov2021
CPAI-QRA double mutation (Q123K and R101A) on the human PAI-1 stable mutant background (K154T, Q319L, M354I and N150H) results in PAI-1 with a greatly extended half life and greatly reduced binding to the important ligand vitronectin.<br>References<br>Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal. Jensen JK, Durand MK, Skeldal S, Dupont DM, Bødker JS, Wind T, Andreasen PA. FEBS Lett. 2004 Jan 2;556(1-3):175-9.<br>Conservation of Critical Functional Domains in Murine Plasminogen Activator Inhibitor-1. Zhi Xu, Rashna D. Balsara, Natalia V. Gorlatova, Daniel A. Lawrence, Francis J. Castellino, and Victoria A. Ploplis. J. Biol. Chem., Apr 2004; 279:17914-20.0.5 mg12155mol-innov2021
CPAI-TPAHuman PAI-1 stable mutant is reacted with an excess of human sc-tPA at physiological pH. The resulting 1:1 molar complex is purified from the remaining tPA by cobalt metal affinity chromatography resin.0.1 mg5950mol-innov2021
CPAI-UPAHuman PAI-1 stable mutant is reacted with  native human urokinase at physiological pH to generate a 1:1 molar complex.0.1 mg5950mol-innov2021
CRP16B2Mouse monoclonal antibody to human C-Reactive Protein (CRP). IgG fraction purified by immobilized Protein G. Detects CRP under non-reducing and reducing conditions. Clone 16B2-3G5, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
CTICorn Trypsin Inhibitor (CTI) is a highly specific inhibitor of trypsin and Factor XIIa that does not affect Factors VIIa, IXa, Xa, or thrombin. CTI forms a one-to-one molar complex with target proteases and is useful for distinguishing between the intrinsic and extrinsic coagulation cascades. CTI is extracted from high quality sweet corn meal into a physiologic buffer then purified by a combination of gel filtration, ion-exchange, and affinity chromatography. The final CTI preparation appears as a single band by SDS-PAGE analysis under both reducing and non-reducing conditions. Preparations of CTI are tested for the ability to prolong the aPTT assay without affecting the PT assay. The specific activity of each lot of CTI is determined, and one unit is defined as the amount of CTI required to double the aPTT of normal human plasma.1.0 mg1360mol-innov2021
CTI-IImmobilized corn trypsin inhibitor is ideal for highly specific reversible binding of Factor XIIa and trypsin in physiologic solutions. The resin is easily removed by centrifugation or filtration following the reaction and captured enzyme can be eluted with chaotropic salt. Immobilized corn trypsin inhibitor is reusable and useful for a range of applications including purification of active Factor XIIa, removal of catalytic trypsin from digest reactions, and depletion of trace residual Factor XIIa from pure zymogen preparations of Factor XII.<br><br> 
<u>Immobilized CTI Protocol</u><br> 
1. Make a binding buffer consisting of 0.1M Tris-HCl, 0.15M NaCl, pH 7.4 (or other suitable physiological buffer such as PBS).<br> 
2. Wash desired amount of immobilized CTI with at least three column volumes of binding buffer.<br> 
3. Resuspend the washed immobilized CTI gel in binding buffer then add the resin to your protein sample.<br> 
4. Incubate mixture with gentle agitation for 5 minutes at room temperature.<br> 
5. Separate the immobilized CTI from the binding reaction by centrifugation or gravity filtration. Retain supernatant as your Factor XIIa/Trypsin depleted protein sample.<br> 
6. To elute bound active enzymes and regenerate immobilized CTI gel, thoroughly wash the resin with binding buffer then elute with 3M Sodium Thiocyanate, 0.1M Sodium Acetate, pH 5.0.<br> 
7. Remove chaotropic salt by extensive dialysis against 4mM Sodium Acetate, 0.15M NaCl, pH 5.3 (or similar appropriate storage buffer with low pH).
1.0 ml8415mol-innov2021
CTI-LCorn Trypsin Inhibitor (CTI) is now available as a convenient essentially salt free lyophilized powder. CTI is a highly specific inhibitor of trypsin and Factor XIIa that does not affect Factors VIIa, IXa, Xa, or thrombin. CTI forms a one-to-one molar complex with target proteases and is useful for distinguishing between the intrinsic and extrinsic coagulation cascades. CTI is extracted from high quality sweet corn meal into a physiologic buffer then purified by a combination of gel filtration, ion-exchange, and affinity chromatography. The final CTI preparation appears as a single band by SDS-PAGE analysis under both reducing and non-reducing conditions. Preparations of CTI are tested for the ability to prolong the aPTT assay without affecting the PT assay. The specific activity of each lot of CTI is determined, and one unit is defined as the amount of CTI required to double the aPTT of normal human plasma.1.0 mg1360mol-innov2021
CTNT1D7Mouse monoclonal antibody to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein A. Clone 1D7-C11-D7, isotype IgG3.0.1 mg3400mol-innov2021
CTNT3B10Mouse monoclonal antibody to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G. Detects cTnT in western blot under non-reducing and reducing conditions. Cross reacts with human Skeletal Troponin T (sTNT, TNNT1). Clone 3B10-G11, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
CTNT8C11Mouse monoclonal antibody to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G. Detects cTnT in western blot under non-reducing and reducing conditions. Cross reacts in western blot with human Skeletal Troponin T (sTNT, TNNT1). <b>Does not react with Skeletal Troponin T in ELISA.</b> Clone 8C11-F7, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
CXCL11C-X-C motif chemokine 11 (CXCL11) is a 73 amino acid Cys-X-Cys chemokine that induces calcium release in interleukin-activated T-cells and may play a role in skin immune responses and CNS diseases which involve T-cell recruitment. It is also known as interferon gamma-inducible protein 9 (IP-9) and interferon-inducible T-cell alpha chemoattractant (I-TAC). CXCL11 is a ligand for the G protein coupled receptors CXCR3 and CXCR7 and is chemotactic for interleukin-stimulated T-cells but not unstimulated T-cells, neutrophils or monocytes. CXCL11 is expressed at high levels in peripheral blood leukocytes, pancreas and liver astrocytes, moderate levels in the thymus, spleen and lung, and at low levels in the placenta, prostate and small intestine. In skin disorders CXCL11 may also be found in epidermal basal layer keratinocytes. CXCL11 is induced by IFNG/IFN-gamma and IFNB1/IFN-beta. Induction by IFNG/IFN-gamma is enhanced by TNF in monocytes, dermal fibroblasts and endothelial cells, and by IL-1 in astrocytes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CXC cytokines are chemotactic cytokines characterized by two cysteines separated by one amino acid that induce directed chemotaxis in nearby responsive cells. Recombinant human CXCL11 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CXCR3 activity verified by intracellular calcium flux using commercially available CXCR3 expressing cells. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CXCL12AC-X-C motif chemokine 12 alpha (CXCL12-alpha) is a 68 amino acid Cys-X-Cys chemokine that is involved in diverse cellular functions including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. CXCL12-alpha is also known as stromal cell-derived factor 1 alpha (SDF-1-alpha) and is processed from the 72 amino acid CXCL12/SDF-1 by proteolytic cleavage after secretion. The C-terminal processing to isoform CXCL12-alpha is reduced by binding to heparin and cell surface proteoglycans. CXCL12 is a ligand for the G protein coupled receptor CXCR4 and is chemotactic for lymphocytes and monocytes but not neutrophils. CXCL12 also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. CXCL12-alpha demonstrates reduced chemotactic activity. CXCL12 is ubiquitously expressed in all tissues with highest levels detected in the liver, pancreas and spleen. CXCL12 directs the migration of hematopoietic cells from liver to bone marrow for myelopoiesis, B-cell lymphopoiesis, large blood vessel formation, and heart ventricular septum formation during embryogenesis. During adulthood CXCL12 plays an important role in angiogenesis by recruiting endothelial progenitor cells from the bone marrow and may be protective after myocardial infarction. CXCL12 inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1 and mutations in CXCL12 are associated with resistance to HIV-1 infection. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CXC cytokines are chemotactic cytokines characterized by two cysteines separated by one amino acid that induce directed chemotaxis in nearby responsive cells. Recombinant human CXCL12 alpha from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CXCR4 activity verified by intracellular calcium flux using THP1 cells as described by Veldkamp et al, Science Signaling 2008. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CXCL12BC-X-C motif chemokine 12 beta (CXCL12-beta) is a 72 amino acid Cys-X-Cys chemokine that is involved in diverse cellular functions including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. CXCL12 is also known as stromal cell-derived factor 1 (SDF-1) and is processed after secretion by proteolytic cleavage to the 68 amino acid CXCL12-alpha/SDF-1-alpha. The C-terminal processing to isoform CXCL12-alpha is reduced by binding to heparin and cell surface proteoglycans. CXCL12 is a ligand for the G protein coupled receptor CXCR4 and is chemotactic for lymphocytes and monocytes but not neutrophils. CXCL12 also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. CXCL12-alpha demonstrates reduced chemotactic activity. CXCL12 is ubiquitously expressed in all tissues with highest levels detected in the liver, pancreas and spleen. CXCL12 directs the migration of hematopoietic cells from liver to bone marrow for myelopoiesis, B-cell lymphopoiesis, large blood vessel formation, and heart ventricular septum formation during embryogenesis. During adulthood CXCL12 plays an important role in angiogenesis by recruiting endothelial progenitor cells from the bone marrow and may be protective after myocardial infarction. CXCL12 inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1 and mutations in CXCL12 are associated with resistance to HIV-1 infection. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CXC cytokines are chemotactic cytokines characterized by two cysteines separated by one amino acid that induce directed chemotaxis in nearby responsive cells. Recombinant human CXCL12 beta from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CXCR4 activity verified by intracellular calcium flux using THP1 cells as described by Veldkamp et al, Science Signaling 2008. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CXCL14C-X-C motif chemokine 14 (CXCL14) is a 77 amino acid Cys-X-Cys chemokine that may play a greater role in the homeostasis of monocyte-derived macrophages rather than inflammation. CXCL14 is an orphaned ligand since a receptor has not yet been determined. CXCL14 is chemotactic for monocytes in the presence of prostaglandin-E2, an attractor and activator of dendritic cells, and chemoattractant for activated NK cells. CXCL14 is constitutively produced without inflammatory stimuli in many normal tissues including the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. It is reduced or absent in most cancer cell lines and weakly expressed in monocyte-derived dendritic cells and unstimulated peripheral blood lymphocytes. CXCL14 production is induced in peripheral blood lymphocytes by LPS. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CXC cytokines are chemotactic cytokines characterized by two cysteines separated by one amino acid that induce directed chemotaxis in nearby responsive cells. Recombinant human CXCL14 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg7140mol-innov2021
CXCL5C-X-C motif chemokine 5 (CXCL5) is a 78 amino acid Cys-X-Cys chemokine that induces chemotactic migration in neutrophils to promote angiogenesis and remodel connective tissues. It is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). CXCL5 is a ligand for the G protein coupled receptor CXCR2 and is expressed in monocytes, eosinophils, platelets, endothelial cells and mast cells. CXCL5 is induced by IL-1 and TNF and repressed by IFNG/IFN-gamma. It is thought to play a role in cancer cell proliferation, migration, and invasion. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CXC cytokines are chemotactic cytokines characterized by two cysteines separated by one amino acid that induce directed chemotaxis in nearby responsive cells. Recombinant human CXCL5 from Molecular Innovations is provided as a native untagged protein. This chemokine is expressed in <i>E. coli</i> then processed, refolded and purified to yield the native, secreted form of the mature chemokine. &gt;98percent pure by SDS-PAGE, HPLC, MALDI-MS and NMR analysis. CXCR4 activity verified by intracellular calcium flux using THP1 cells as described by Veldkamp et al, Science Signaling 2008. Add deionized water to desired volume, aliquot and freeze unused portion.0.025 mg4590mol-innov2021
CYFVIIIKT-TOTFactor VIII (aka Factor VIII:C or Antihemophilic Globulin) is a glycoprotein zymogen that circulates in a stabilized non-covalent complex with von Willebrand Factor (vWF). Following activation by thrombin or Factor Xa, Factor VIIIa dissociates from vWF and catalyzes the activation of Factor X by Factor IXa in the amplification phase of coagulation. Factor VIIIa activity is quickly decreased by spontaneous dissociation and proteolytic degradation by activated Protein C, Factor Xa and Factor IXa. Hemophilia A is caused by mutations in the Factor VIII gene; a majority of patients have decreased Factor VIII plasma levels while 5% of patients have normal levels of nonfunctioning protein. The sensitive quantitative measurement of total cynomolgus macaque monkey (Macaca fascicularis) Factor VIII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The average normal plasma level of Factor VIII is defined as 1.0 IU/ml and the normal range is 0.4-1.8 IU/ml. Hemaophilia A patients are classified by the following Factor VIII levels: 0.05-0.25 IU/ml = mild, 0.01-0.05 IU/ml = moderate, and <0.01 IU/ml = severe. Normal values of Factor VIII in cyno plasma have not been conclusively determined but are believed to be similar to human plasma. The assay measures total cyno Factor VIII in the 0.003-1.42 IU/ml range. Samples giving cyno Factor VIII levels above 1.42 IU/ml should be diluted in blocking buffer before use. 1:8 and 1:16 dilutions for normal plasma, or 1:4 and 1:8 dilutions for Haemophiliac plasma, are suggested for best results.<br><br>Cyno Factor VIII will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-cyno Factor VIII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of cyno plasma. Color development is proportional to the concentration of Factor VIII in the samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Factor VIII level in the cyno plasma standard provided is calibrated against a human plasma secondary standard that is referenced to the WHO or ISTH International Standard.</strong>1 kit8415mol-innov2021
CY-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg3060mol-innov2021
CY-IGG1Purified from normal cynomolgus macaque (Macaca fascicularis) monkey serum by affinity chromatography. Heavy chain isotype confirmed by rapid lateral flow isotyping kit. &gt;95percent pure by SDS-PAGE.0.1 mg3315mol-innov2021
CYIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total cynomolgus macaque (Macaca fascicularis) monkey IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react significantly with human, mouse, rat, dog, sheep, pig or rabbit IgG.</b> The concentration of IgG in normal cyno monkey serum ranges from 5 to 12 mg/ml. The assay measures cyno monkey IgG in the 0.1-100 ng/ml range. Samples giving cyno monkey IgG levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000 to 1:10,000,000 dilution for serum is suggested for best results. Cyno monkey IgG will bind to the monoclonal capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled monoclonal anti-cyno IgG primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with horseradish peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of cyno monkey IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified cyno monkey IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6545mol-innov2021
CYPAIRecombinant cynomolgus (cyno) monkey PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies.0.5 mg15640mol-innov2021
CYPAI-CRecombinant cynomolgus (cyno) monkey PAI-1 is provided cleaved at P3-P4 residues via immobilized elastase: <1percent active. Useful for various control experiments requiring a non-reactive, reactive loop inserted species of PAI-1.0.5 mg15640mol-innov2021
CYPAI-LRecombinant cynomolgus (cyno) monkey PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies.0.5 mg15640mol-innov2021
CYPLGPrepared from frozen cynomolgus macaque monkey (Macaca fascicularis) plasma by immobilized lysine chromatography. Cyno monkey plasmin available by request.1.0 mg6800mol-innov2021
CYPLGKT-TOTPlasminogen is a single chain glycoprotein zymogen and is the precursor of the fibrinolytic enzyme plasmin. Plasminogen deficiencies are classified as hypoplasminogenemia (Type I) or dysplasminogenemia (Type 2) and are associated with decreased extracellular fibrin clearance leading to mucous membrane lesions and ligneous conjunctivitis. The sensitive quantitative measurement of total cynomolgus macaque monkey (Macaca fascicularis) plasminogen antigen in plasma, serum, or cell culture media samples is easily performed with this 96 well strip format ELISA kit. <b>Plasminogen, plasmin and plasmin antiplasmin complex will be detected by the assay.</b> The concentration of plasminogen in normal human plasma is 195 ug/ml. Normal values of plasminogen in cyno plasma have not been conclusively determined but are believed to be similar to human plasma. The assay measures total cyno plasminogen in the 0.5-100 ng/ml range. Samples giving cyno plasminogen levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:10,000-1:100,000 dilution for plasma is suggested for best results. Cyno plasminogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-cyno plasminogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of plasminogen in the samples. A standard calibration curve is prepared using dilutions of purified plasminogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
CYSACyno albumin is prepared from cynomolgus (cyno) monkey plasma by proprietary fractionation methods and lyophilized. Albumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. >95percent pure by SDS-PAGE.  Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.10 mg3400mol-innov2021
CY-SER-GFPrepared from frozen cyno monkey serum using immobilized Protein A.50 ml11305mol-innov2021
DFBGNPrepared from fresh US origin dog (canine) plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg1530mol-innov2021
DFBGN-FITCDog (canine) fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh dog plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg8755mol-innov2021
DFBGN-SDog (canine) fibrinogen is allowed to clot then is dissociated using non-denaturing conditions. The soluble fibrin clot is then stored under acidic conditions. The soluble fibrin will reassemble into an insoluble clot when pH is restored to neutral (e.g. by adding one-tenth volume of 10X PBS to the soluble fibrin). SDS-PAGE shows partially crosslinked fibrin with no observable free alpha, beta or gamma chain subunits. No detectable thrombin or plasmin activity is observed in the final product.1.0 mg5015mol-innov2021
D-FPIPR-pNAThe thrombin substrate provide by our company is chemically and functionally identical to Chromogenix S-2238. Each 25 mg of substrate is lyophilized with 60 mg mannitol as a bulking agent. For best results add 4.0 ml of 1mM HCl directly to vial to make a 10mM stock solution then aliquot and freeze. Dilute 1:50 in PBS or TBS to make an 0.2mM working solution. Add 0.1 ml test sample to 0.9 ml substrate and monitor color development at 405nm.
<br><br>
Formula: H-D-Phe-Pip-Arg-pNA . 2HCl<br>
Mr: 625.6 Da
25 mg3995mol-innov2021
DG-GFPurified from normal plasma by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.100 mg4335mol-innov2021
DH5ADH5-alpha strain chemically competent cells from Molecular Innovations are an all purpose reagent for general cloning, sub-cloning and plasmid isolation. For a transformation efficiency of at least 1x106 simply thaw a tube of cells on ice, add 1-5 ul of DNA, gently mix and incubate on ice for 2-5 minutes, then spread 50-100 ul onto a pre-warmed culture plate. For greater transformation efficiencies heat shock at 37C for 1 minute before plating, or heat shock at 42C for 30 seconds then add SOC media and shake at 225 rpm at 37C for 1 hour before plating. Conveniently supplied as a pack of 5 single use 0.2 ml aliquots.<br><br> 
Genotype: F<sup>-</sup> &Phi;80<i>lac</i>Z&Delta;M15 &Delta;(<i>lac</i>ZYA-<i>arg</i>F) U169 <i>rec</i>A1 <i>end</i>A1 <i>hsd</i>R17(r<sub>k</sub><sup>-</sup>, m<sub>k</sub><sup>+</sup>) <i>pho</i>A <i>sup</i>E44 <i>thi</i>-1 <i>gyr</i>A96 <i>rel</i>A1 &lambda;<sup>-</sup>
1.0 ml1700mol-innov2021
DK-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free.50 mg1445mol-innov2021
DNTPUltra pure deoxynucleotide (dNTP) mix from Molecular Innovations is >99% pure and PCR grade. It is supplied as a 10mM equimolar mix of dATP, dCTP, dTTP and dGTP in a clear aqueous solution at pH 8.5. One microliter of the dNTP Mix in a 50?l reaction will give a final dNTP concentration of 200?M for each dNTP. The mix is certified free from bacterial and human DNA, DNases, RNases, nicking activity and proteases. Suitable for multiple molecular biology applications including PCR, qPCR, RT-PCR, mutagenesis, DNA labeling and DNA sequencing.1.0 ml1190mol-innov2021
DPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active canine (dog) PAI-1 in plasma samples is easily performed with this 96 well strip format ELISA kit. The assay measures active PAI-1 in the 0.2-100 ng/ml range. Samples giving mouse PAI-1 levels above 100 ng/ml should be diluted in blocking buffer before use. Normal plasma should be applied directly to the plate for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay.</b> After appropriate washing steps, anti-dog PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8415mol-innov2021
DPAIKT-TOTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis.  The sensitive quantitative measurement of total canine (dog) PAI-1 antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The assay measures mouse PAI-1 in the 0.2-100 ng/ml range. Samples giving dog PAI-1 levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:5-1:20 dilution for normal dog plasma is suggested for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Dog PAI-1 will bind to the capture antibody coated on the microtiter plate. <b>Free, latent, and complexed PAI-1 will be detected by the assay.</b> After appropriate washing steps, biotinylated anti-dog PAI-1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of dog PAI-1 in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified dog PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8415mol-innov2021
DPLGPrepared from fresh US origin dog (canine) plasma by immobilized lysine chromatography. Dog plasmin available by request.1.0 mg6800mol-innov2021
DPLMPrepared from dog (canine) plasminogen by activation with human uPA. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg8075mol-innov2021
DPREN-HISRecombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification.0.1 mg8245mol-innov2021
DREN-HISRenin is an aspartyl protease that is specific for only one substrate, angiotensinogen. Molecular Innovations dog renin is produced from the proenzyme prorenin by proteolytic cleavage of a 43 amino acid N-terminal prosegment using limited enzymatic digestion by immobilized trypsin. Conversion to active renin is >98 percent.0.1 mg8245mol-innov2021
DSAAlbumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. Prepared from US origin dog (canine) plasma by proprietary fractionation methods and lyophilized. >95percent pure by SDS-PAGE.  Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.100 mg3400mol-innov2021
DTHROMCanine (dog) thrombin is prepared from purified dog prothrombin by activation with Saw Scaled Viper Venom. The venom was removed after activation. Complete activation is observed on SDS-PAGE.0.05 mg5015mol-innov2021
DUPAActive two-chain canine urokinase (uPA), recombinantly produced in insect cells.0.05 mg4590mol-innov2021
D-VLK-pNAThe plasmin substrate provide by our company is chemically and functionally identical to Chromogenix S-2251. Each 25 mg of substrate is lyophilized with 60 mg mannitol as a bulking agent. For best results add 4.5 ml of 1mM HCl directly to vial to make a 10mM stock solution then aliquot and freeze. Dilute 1:50 in PBS or TBS to make an 0.2mM working solution. Add 0.1 ml test sample to 0.9 ml substrate and monitor color development at 405nm.
<br><br>
Formula: H-D-Val-Leu-Lys-pNA . 2HCl<br>
Mr: 551.6 Da
25 mg3995mol-innov2021
ECOTINSerine protease inhibitor purified from E. coli.  At least 98percent pure as determined by SDS-PAGE.
References:
1. Seymour, J.L. et al. (1994) Biochemistry 33:3949-3958.
1.0 mg10625mol-innov2021
ECV-IIPurified from Echis Carinatus Viper (Indian saw-scaled viper) Venom. Metal dependant endopeptidase that cleaves the Arg332-Ile323 bond in prothrombin to form meizothrombin. This protease is inhibited by EDTA, DTT and o-phenanthroline.  ECV-II is a single chain glycoprotein and is highly pure and homogenous by SDS-PAGE.0.1 mg4675mol-innov2021
ELAS-ICleaves PAI-1 between the P3 and P4 residues to create a loop-inserted species that is non-inhibitory towards the target enzymes uPA and tPA.1.0 ml5950mol-innov2021
EQPKHorse Prekallikrein is purified from horse plasma by a combination of conventional and affinity chromatographic steps. Zymogen precursor of the plasma serine protease kallikrein. Prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contact activation, kinin formation and fibrinolysis. Horse Prekallikrein purity is &gt;95percent by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.0.1 mg8670mol-innov2021
EQPKAHorse Kallikrein is purified from horse plasma by a combination of conventional and affinity chromatographic steps. Activation of Prekallikrein with Factor alpha-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Horse Kallikrein purity is &gt;95percent by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.0.1 mg11390mol-innov2021
EQPLGPrepared from fresh horse plasma by immobilized lysine chromatography. Please inquire about the availability of active horse plasmin.1.0 mg3060mol-innov2021
EQSAAlbumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. Prepared from US origin equine (horse) plasma by proprietary fractionation methods and lyophilized. >95percent pure by SDS-PAGE.  Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.100 mg3400mol-innov2021
FIBPrepared from fresh human plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.25 mg1700mol-innov2021
FIB-BIOHuman fibrinogen amino terminal labeled with biotin. Prepared from fresh human plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.10 mg1700mol-innov2021
FIB-CNBRPrepared from plasminogen depleted human fibrinogen by cyanogen bromide cleavage then lyophilized. Add deionized water to desired volume, aliquot and freeze unused portion.1.0 mg1700mol-innov2021
FIB-FITCHuman fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh human plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.10 mg1700mol-innov2021
FIB-SNormal human plasma clots are dissociated using non-denaturing conditions in which non fibrin bound plasma proteins are removed. The soluble human fibrin clot is then stored under acidic conditions. The soluble human fibrin will reassemble into an insoluble clot when pH is restored to neutral (e.g. by adding one-tenth volume of 10X PBS to the soluble fibrin). SDS-PAGE shows partially crosslinked fibrin with no observable free alpha, beta or gamma chain subunits. No detectable thrombin or plasmin activity is observed in the final product.1.0 mg1700mol-innov2021
FIB-S-FITCNormal human plasma clots are dissociated using non-denaturing conditions in which non fibrin bound plasma proteins are removed. The soluble human fibrin clot is then stored under acidic conditions. The soluble human fibrin will reassemble into an insoluble clot when pH is restored to neutral (e.g. by adding one-tenth volume of 10X PBS to the soluble fibrin). SDS-PAGE shows partially crosslinked fibrin with no observable free alpha, beta or gamma chain subunits. No detectable thrombin or plasmin activity is observed in the final product. Labeling efficiency was measured in 0.1M HEPES; 0.1M NaCl; 0.1% SDS; pH 7.4.1.0 mg3400mol-innov2021
FIX13F42F6Mouse monoclonal antibody to human Factor IX. IgG fraction purified by immobilized Protein G. Detects Factor IX and Factor IXa under non-reducing and reducing conditions. Epitope localized to the heavy chain. Isotype IgG1Kappa.1.0 mg8670mol-innov2021
FL-INFPRFluorescein labeled ATA-Phe-Pro-Arg-CMK.0.1 mg4845mol-innov2021
FPAIA single mutation at the P1 position of PAI-1 alters the target specificity of PAI-1 from the plasminogen activators tPA and uPA to Cathepsin G. This mutant contains a P1 Phenylalanine in place of the wild type Arginine residue (R346F) resulting in an inhibitor with the specificity of antichymotrypsin.0.5 mg12155mol-innov2021
FPRCK-TPAPrepared from human tPA by incubation with an excess of  ATA-Phe-Pro-Arg-CMK. After labeling at the active site, remaining free peptide is removed by dialysis.0.1 mg6885mol-innov2021
FV12C5Mouse monoclonal antibody to human Factor V. IgG fraction purified by immobilized Protein G. Isotype IgG1Kappa.0.1 mg3400mol-innov2021
FV12C5-BIOBiotin labeled mouse monoclonal antibody to human Factor V. IgG fraction purified by immobilized Protein G. Clone 12C5, isotype IgG1Kappa.0.1 mg5185mol-innov2021
FV14G5Mouse monoclonal antibody to human Factor V. IgG fraction purified by immobilized Protein G. Clone 14G5-G11, isotype IgG1Kappa.0.1 mg3400mol-innov2021
FV14G5-BIOBiotin labeled mouse monoclonal antibody to human Factor V. IgG fraction purified by immobilized Protein G. Clone 14G5-G11, isotype IgG1Kappa.0.1 mg5185mol-innov2021
FVII11G42D8Mouse monoclonal antibody to Human Factor VII. IgG fraction purified by immobilized Protein G. Isotype IgG2bKappa.1.0 mg8670mol-innov2021
FVII11G42D8-BIOBiotin labeled mouse monoclonal antibody to Human Factor VII. IgG fraction purified by immobilized Protein G. Isotype IgG2bKappa.1.0 mg10370mol-innov2021
FVIII12H12Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 12H12-H5E5, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII14E10Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 14E10, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII14E8Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 14E8-F7, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII15D9Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 15D9-F9A11, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII1C2Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 1C2-G10F10, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII9C8Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 9C8-E10D8, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FVIII9F5Mouse monoclonal antibody to Human Factor VIII. IgG fraction purified by immobilized Protein G. Detects Factor VIII under non-reducing conditions. Epitope localized to the heavy chain. Clone 9F5, isotype IgG1 kappa.0.1 mg3400mol-innov2021
FX3C8B9Mouse monoclonal antibody to human Factor X. IgG fraction purified by immobilized Protein G. Isotype IgG1Kappa.1.0 mg8670mol-innov2021
FX4E3F8Mouse monoclonal antibody to human Factor X. IgG fraction purified by immobilized Protein G. Isotype IgG1.1.0 mg8670mol-innov2021
FXI14F8Mouse monoclonal antibody to Human Factor XI. IgG fraction purified by immobilized Protein G. Detects Factor XI and Factor XIa under non-reducing and reducing conditions. Epitope localized to the light chain. Clone 14F8-F10, isotype IgG1 Kappa.<br><br>0.1 mg3400mol-innov2021
FXI2B11Mouse monoclonal antibody to Human Factor XI. IgG fraction purified by immobilized Protein G. Detects Factor XI and Factor XIa under non-reducing and reducing conditions. Epitope localized to the heavy chain. Clone 2B11-E5F6, isotype IgG1 Kappa.<br><br>
<br><br>
0.1 mg3400mol-innov2021
FXI9C9Inhibitory mouse monoclonal antibody to Human Factor XI that extends the clotting time of normal human plasma. IgG fraction purified by immobilized Protein G. Detects Factor XI and Factor XIa under non-reducing conditions. Epitope localized to the heavy chain. Clone 9C9-E10F7, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXI9C9-BIOBiotin labeled inhibitory mouse monoclonal antibody to Human and Mouse Factor XI that extends the clotting time of normal human plasma. IgG fraction purified by immobilized Protein G. Detects Factor XI and Factor XIa under non-reducing conditions. Epitope localized to the heavy chain. Clone 9C9-E10F7, isotype IgG1 Kappa.0.1 mg6035mol-innov2021
FXII11B9Mouse monoclonal antibody to Human Factor XII. IgG fraction purified by immobilized Protein G. Detects Factor XII, Factor XIIa and Factor beta-XIIa under non-reducing conditions. Epitope localized to the heavy chain between residues Ile 1 and Thr 279. Clone 11B9-4F8, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
FXII11E3Mouse monoclonal antibody to Mouse Factor XIIa. IgG fraction purified by immobilized Protein G. Mildly detects mouse Factor XIIa. Clone 11E3-C11D9D12, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII15G5Mouse monoclonal antibody to Mouse Factor XIIA. IgG fraction purified by immobilized Protein G. Detects mouse Factor alpha-XIIa. Strongly cross-reacts with Human Factor XII and human alpha-Factor XIIa. Clone 15G5-H8C11, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII20B2Mouse monoclonal antibody to Human Factor XII. IgG fraction purified by immobilized Protein G. Detects Factor XII and Factor XIIa under non-reducing and reducing conditions. Epitope localized to the heavy chain between residues Thr 279 and Arg 353. Clone 20B2-5B5, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
FXII20B2-BIOBiotin labeled mouse monoclonal antibody to Human Factor XII. IgG fraction purified by immobilized Protein G. Detects Factor XII and Factor XIIa under non-reducing and reducing conditions. Epitope localized to the heavy chain between residues Thr 279 and Arg 353. Clone 20B2-5B5, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII20C8Mouse monoclonal antibody to Human Factor XII. IgG fraction purified by immobilized Protein G. Detects Factor XII and Factor XIIa under non-reducing and reducing conditions. Epitope localized to the heavy chain. Clone 20C8-6F9F1, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
FXII22H6Mouse monoclonal antibody to Mouse Factor XIIa. IgG fraction purified by immobilized Protein G. Weakly detects Mouse Factor XIIa, strongly detects human Factor XII and XIIa. Strongly cross-reacts with Human Factor XII. Clone 22H6-H12C12, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII23E10Mouse monoclonal antibody to Mouse Factor XII. IgG fraction purified by immobilized Protein G. Strongly detects mouse Factor XIIa, mildly detects human Factor XII and alpha-XII, and strongly detects human Factor beta-XII. Cross-reacts with Human Factor XII. Clone 23E10-D12A11, isotype IgG1 Lambda.0.1 mg5185mol-innov2021
FXII2A6Mouse monoclonal antibody to Mouse Factor XII. IgG fraction purified by immobilized Protein G. Detects Factor XII, Factor XIIa and Factor beta-XIIa under non-reducing and reducing conditions. Weakly cross-reacts with Human Factor XII. Epitope localized to the light chain. Clone 2A6-F12A7, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII2D10Inhibitory mouse monoclonal antibody to Mouse Factor XIIa that extends the clotting time of normal mouse plasma. IgG fraction purified by immobilized Protein G. Strongly detects mouse Factor XIIa. Epitope localized to the light chain. Clone 2D10-B2F12, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
FXII5B5Mouse monoclonal antibody to Mouse Factor XII. IgG fraction purified by immobilized Protein G. Strongly detects mouse Factor XIIa, strongly detects human Factor XII and alpha-XII, and strongly detects human Factor beta-XII. Cross-reacts with Human Factor XII. Clone 5B5, isotype IgG1 Lambda.0.1 mg5185mol-innov2021
FXII6G8Mouse monoclonal antibody to Mouse Factor XIIa. IgG fraction purified by immobilized Protein G. Strongly detects Mouse Factor XIIa. Strongly cross-reacts with human Factor XII and alpha-XIIa. Clone 6G8-D7, isotype IgG1 Kappa.0.1 mg5185mol-innov2021
GAM-HRPHorseradish peroxidase conjugated goat anti-mouse IgG, Heavy & Light chain specific. Affinity purified and adsorbed against bovine, horse, and human serum proteins. Monospecific for mouse IgG, heavy and light chains, as determined by immunoelectrophoresis against normal mouse serum. Cross-reactivity with normal bovine, horse, and human serum is <2percent by direct solid phase immunoassay. Recommended starting dilution for ELISA is 1:10,000 but proper working dilution must be optimized by the end user.
<br>Please be aware that our minimum order is $50.
0.01 ml510mol-innov2021
GAR-HRPHorseradish peroxidase conjugated goat anti-rabbit IgG, Heavy & Light chain specific. Affinity purified and adsorbed against bovine, horse, human, and mouse serum proteins. Monospecific for rabbit IgG, heavy and light chains, as determined by immunoelectrophoresis against normal rabbit serum. Cross-reactivity with normal bovine, horse, human, and mouse serum is <2percent by direct solid phase immunoassay. Recommended starting dilution for ELISA is 1:10,000 but proper working dilution must be optimized by the end user.
<br>Please be aware that our minimum order is $50.
0.01 ml510mol-innov2021
GART-HRPHorseradish peroxidase conjugated goat anti-rat IgG, Heavy &amp; Light chain specific. Affinity purified and adsorbed against bovine, horse, human, mouse, and rabbit IgG. Reacts with rat IgG, Fab, and Fc fragments as determined by immunodiffusion, immunoelectrophoresis, and ELISA. No detectable cross-reactivity with purified bovine, horse, human, mouse, and rabbit IgG by immunoelectrophoresis and ELISA. Recommended starting dilution for ELISA is 1:5,000 but proper working dilution must be optimized by the end user. 
<br>Please be aware that our minimum order is $50.
0.01 ml510mol-innov2021
GASRbPAIPolyclonal antiserum (host goat).1.0 ml6290mol-innov2021
GASRbPAI-GFPolyclonal antibody (host goat). IgG fraction purified by immobilized Protein G.1.0 mg6290mol-innov2021
GASRbPAI-GF-BIOBiotin labeled polyclonal antibody (host goat). IgG fraction purified by immobilized Protein G.1.0 mg6885mol-innov2021
GASRbPAI-GF-FITCFITC labeled polyclonal antibody (host goat). IgG fraction purified by immobilized Protein G.1.0 mg6885mol-innov2021
GASRbPAI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host goat). IgG fraction purified by immobilized Protein G.1.0 mg6885mol-innov2021
GASRbPAI-GF-HTPolyclonal antibody (host goat). Affinity purified by immobilized rabbit PAI-1.0.1 mg7990mol-innov2021
GGACKGlu-Gly-Arg-Chloromethylketone. Also known as EGR-chloromethylketone, EGR-CMK, and GGACK.5.0 mg4420mol-innov2021
GGACK-BIOBiotinylated Glu-Gly-Arg-Chloromethylketone (EGRCK). Potent and specific irreversible inhibitor of Factor Xa. Also known as EGR-chloromethylketone, EGR-CMK, EGRCK, and GGACK.1.0 mg8840mol-innov2021
GGACK-FITCFluorescein labeled Glu-Gly-Arg-Chloromethylketone (EGRCK). Potent and specific irreversible inhibitor of Factor Xa. Also known as EGR-chloromethylketone, EGR-CMK, EGRCK, and GGACK.1.0 mg10625mol-innov2021
GLYCPAIGlycolyslated human PAI-1 produced in insect cells with a molecular weight of 46,000 Da. The stable mutant contains four mutations (K154T, Q319L, M354I and N150H) to confer additional stability to the otherwise labile molecule.0.5 mg16575mol-innov2021
GLYDPAI-I91LGlycosylated dog PAI-1 produced in insect cells with a single conservative mutation (Isoleucine 91 to Leucine) to increase stability.0.5 mg16575mol-innov2021
GLYDPAI-LGlycosylated wild type dog PAI-1 produced in insect cells. Latent form.0.5 mg16575mol-innov2021
GLYHPAI-AGlycosylated wild type human PAI-1 produced in insect cells with molecular weight of ~46,000 Da.  Active form.0.5 mg16575mol-innov2021
GLYHPAI-A-AF488Glycosylated wild type human PAI-1 produced in insect cells with molecular weight of ~46,000 Da. Active form labeled with Alexa Fluor 488 at primary amines (Abs: 495, Em: 519).0.5 mg16575mol-innov2021
GLYHPAI-LGlycosylated wild type human PAI-1 produced in insect cells with molecular weight of ~46,000 Da.  Latent form.0.5 mg16575mol-innov2021
GLYMPAI-I91LGlycosylated mouse PAI-1 produced in insect cells with a single conservative mutation (Isoleucine 91 to Leucine) to increase stability.0.5 mg16575mol-innov2021
GLYRPAI-I91LGlycosylated rat PAI-1 produced in insect cells with a single conservative mutation (Isoleucine 91 to Leucine) to increase stability.0.5 mg16575mol-innov2021
GP2B3APlatelet membrane glycoproteins IIb and IIIa (GPIIb and GPIIIa) constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of 2 disulfide-linked subunits GPIIb (MW = 125,000) and GPII (MW= 23,000) while GPIIIa has only one polypeptide chain (MW= 108,000). GPIIbIIIa migrates on gels as follows: GPIIb 136,000 non-reduced and 125,000 reduced. GPIIIa is 97,000 non-reduced and 108,000 reduced. Protein concentration is determined via the Bradford method.1.0 mg6205mol-innov2021
GT-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free.50 mg1445mol-innov2021
H14H7Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
H14H7-BIOBiotin labeled monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.0.15 mg9605mol-innov2021
H27B6Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
H34G6Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
H4B3Inhibitory monoclonal antibody produced in mouse. It binds to a conformational epitope on recombinant non-glycosylated PAI-1 converting it to the latent form in a time-dependent manner. IgG fraction purified by immobilized Protein A. Isotype IgG.<br> 
References:<br> 
Evidence for a Pre-latent Form of the Serpin Plasminogen Activator Inhibitor-1 with a Detached B-Strand 1C. Dupont DM et al. Journal of Biological Chemistry 281, 36071–36081 (2006).<br>
1.0 mg10115mol-innov2021
H6C5Detection monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
H77A10Capture monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
H77B6Detection monoclonal antibody produced in mouse. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg10115mol-innov2021
HA1ACAn acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.5 mg4845mol-innov2021
HA1ATAn acute-phase plasma protein found at 290 mg per 100 ml that functions as a protease inhibitor. Clinically, its deficiency is associated with two major diseases: pulmonary emphysema and early onset/juvenile hepatic cirrhosis. It is elevated in inflammatory conditions, malignancies, liver disease and pregnancy and also after surgical trauma and use of oral contraceptives. The simultaneous quantitative determination of alpha-1-PI and ceruloplasmin permits differential diagnosis of liver afflictions. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.5.0 mg4845mol-innov2021
HA1ATKT-TOTAlpha-1-Antitrypsin (A1AT), also known as alpha-1 protease inhibitor (A1PI), is a glycosylated 394 amino acid 52 kDa plasma serpin that is the most abundant proteinase inhibitor in plasma. Although it does inhibit trypsin and similar proteinases, its physiological target is neutrophil elastase. Individuals with genetically low expression of A1AT are at risk for tissue and organ damage due to unchecked neutrophil elastase activities. A1AT deficiency is associated with respiratory complications such as chronic obstructive pulmonary disease. Mutations in A1AT can lead to non-functional proteins that polymerize and accumulate in the liver as in infantile hepatic cirrhosis. These conditions are life threatening and require regular injections of purified A1AT from human plasma. The sensitive quantitative measurement of total human A1AT antigen in plasma, serum, saliva, and urine is easily performed with this 96 well strip format ELISA kit. <b>Free and complexed A1AT will be detected by the assay.</b> The average concentration of A1AT in normal human plasma and serum is 1.3 ng/ml. The assay measures total human A1AT in the 0.1-100 ng/ml range. Samples giving human A1AT levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:200,000 to 1:2,000,000 dilution for normal human plasma and serum samples, 1:10 dilution for urine samples, and no dilution for saliva is suggested for best results. 
 
Human A1AT will bind to the affinity purified capture antibody coated on the microtiter plate. Complexed and free A1AT will react with the antibody on the plate. After appropriate washing steps, biotinylated polyclonal anti-human A1AT primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody, which is proportional to the total A1AT present in the samples, is reacted with horseradish peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human A1AT. Color development is proportional to the concentration of A1AT in the samples. All reagents and standards are provided in these ELISA kits.
1 kit6715mol-innov2021
HA1GPFound in human plasma in concentrations of 55-140 mg per 100 ml. Classical standard glycoprotein for studies on the structure of the oligosaccharide units. Carbohydrate content is 40percent. Its biological significance is unknown although it can bind progesterone 15 times as strongly as albumin. Sialic-acid-deficient alpha-1-AG has an affinity for vitamin B-12. Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein:haptolobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.10 mg4420mol-innov2021
HA2APEfficiently inhibits the plasminogen-activator-induced lysis of fibrin clots. Found in plasma at about 70 ug per ml. Alpha-antiplasmin-deficiency is a rare coagulation disorder which allows unrestrained fibrinolytic activity. Individuals with this condition may receive therapeutic A2AP prior to surgery to prevent postoperative hemorrhaging. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg8075mol-innov2021
HA2APKT-TOTAlpha-2-antiplasmin is the major circulating inhibitor of plasmin. It plays a role in the regulation of intravascular fibrinolysis. Decreased levels of alpha-2-antiplasmin may play an important role in the increased capacity of the fibrinolytic function and may be beneficial in the treatment of thrombotic diseases, acute pulmonary embolism, and hepatic repair. The sensitive quantitative measurement of total human alpha-2-antiplasmin antigen in samples is easily performed with this 96 well strip format ELISA kit. The normal human concentration of antiplasmin is 70 ug/ml in plasma and 47.6 ug/ml in serum. The assay measures total antiplasmin in the 0.1-100 ng/ml range. Samples giving human antiplasmin levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:10,000-20,000 dilution for plasma is suggested for best results. Human antiplasmin will bind to the capture antibody coated onto a micro titer plate. <b>Free and complexed antiplasmin will bind to the plate and will be detected by the assay. This kit does not cross react with mouse antiplasmin.</b> After appropriate washing steps, biotin labeled anti human antiplasmin primary antibody binds to the antiplasmin. Excess antibody is washed away, and bound antibody is reacted with peroxidase conjugated streptavidin. TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of antiplasmin in the samples. A standard calibration curve is prepared using dilutions of purified antiplasmin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>1 kit8415mol-innov2021
HA2GPFound in human serum at 60 mg per 100 ml. This protein is a negative acute-phase reactant. Clinically, concentrations are reduced in cancer patients. AHSG levels are positively correlated with gestational diabetes and negatively correlated with neonatal skeletal development. Studies show AHSG to be present at high concentrations in the peritoneal fluids of patients with endometriosis. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg4250mol-innov2021
HA2MGA major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc and is a proteinase inhibitor that controls the clotting and fibrinolytic system. Clinically levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Conveniently supplied in 1 mg aliquots. Add deionized water to original volume, aliquot and freeze unused portion.5.0 mg5695mol-innov2021
HA2MGKTAlpha-2-macroglobulin (A2M) is a circulating 720 kDa homotetramer expressed in the liver which captures a wide range of plasma proteinases including plasmin and thrombin. Each monomer contains an internal thiol ester, a transglutaminase reactive site, zinc and receptor binding sites, and a bait region which when cleaved induces a conformational change trapping the proteinase. Serum A2M levels are decreased in acute pancreatitis and increased in chronic liver disease and nephrotic syndrome. The sensitive quantitative measurement of total human alpha-2-macroglobulin in samples is easily performed with this 96 well strip format ELISA kit. The normal human concentration of macroglobulin is 1.2 mg/ml in plasma. The assay measures total macroglobulin in the 1-250 ng/ml range. Samples giving human macroglobulin levels above 250 ng/ml should be diluted in blocking buffer before use. A 1:100,000 dilution for plasma is suggested for best results. Human macroglobulin will bind to the affinity purified capture antibody coated onto a micro titer plate. After appropriate washing steps, biotinylated primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with horseradish peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is directly proportional to the concentration of macroglobulin in the samples. A standard calibration curve is prepared using dilutions of purified macroglobulin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
HAP1E94For ELISA and western blot of human antiplasmin.  Detects purified antiplasmin and antiplasmin in plasma, under both native and reducing conditions. IgG fraction purified by immobilized Protein G. Clone 1E94, isotype IgG.1.0 mg7990mol-innov2021
HAPCActivated Protein C (APC) is a serine protease derived from the two chain vitamin K dependent zymogen Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from Protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.0.1 mg5525mol-innov2021
HAPO-A175percent of Apo A in HDL is Apo AI. Levels of Apo AI are inversely related to the risk of coronary heart disease. Apo AI is also thought to activate LCAT (lecithin cholesterol acyl tranferase). In normal plasma, Apo AI levels range from 90-130 mg per 100 ml. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg5355mol-innov2021
HAPOA1KTApolipoprotein A-I (ApoA1) is the major protein constituent of high density lipoprotein which is the densest of the lipoprotein aggregates. ApoA1 participates in the reverse transport of cholesterol from tissues to the liver and is a cofactor for lecithin cholesterol acyl tranferase. The ratio of ApoA1 to Apolipoprotein B (ApoB), the primary component of low density lipoprotein, is an effective predictor of cardiovascular disease. The sensitive quantitative measurement of total human ApoA1 antigen in plasma, serum, urine & other biological fluid samples is easily performed with this 96 well strip format ELISA kit. ApoA1 is present in human plasma and serum at a concentration of 0.75-1.6 mg/ml in adult males, 0.8-1.75 mg/ml in adult females, 0.38-1.06 mg/ml in newborns, and 0.6-1.67 mg/ml in children. The ratio of ApoA1/ApoB ranges from 0.85-2.24 in males and 0.76-3.23 in females. The assay measures total human ApoA1 in the 5-5000 ng/ml range. Samples giving human ApoA1 levels above 5000 ng/ml should be diluted in diluent before use. A 1:40,000 to 1:80,000 dilution for normal human plasma is suggested for best results. 
 
Human ApoA1 will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, monoclonal anti-human ApoA1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the peroxidase conjugated secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human ApoA1. Color development is proportional to the concentration of total ApoA1 antigen in the samples.All reagents and standards are provided in these ELISA kits.
1 kit8415mol-innov2021
HAPO-A225percent of Apo A in HDL is Apo AII. Levels of Apo AII in normal plasma range from 30-50 mg per 100 ml. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg5355mol-innov2021
HAPO-BApolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100 and Apo B-48. The first is found in VLDL and LDL and is produced by the liver. The second is found in chylomicrons and originates in the intestine. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg4930mol-innov2021
HAPOBKTApolipoprotein B (ApoB) is the primary protein constituent of low density lipoprotein, very-low density lipoprotein, and chylomicrons. ApoB directs cholesterol and triglyceride containing particles to tissues by ApoB receptor binding and internalization. The ratio of ApoA1 to Apolipoprotein B (ApoB), the primary component of low density lipoprotein, is an effective predictor of cardiovascular disease. The sensitive quantitative measurement of total human ApoB antigen in plasma, serum, urine and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. ApoB is present in human plasma and serum at a concentration of 0.5-1.25 mg/ml in adult males, 0.45-1.2 mg/ml in adult females, 0.11-0.31 mg/ml in newborns, and 0.23-1.39 mg/ml in children. The ratio of ApoA1/ApoB ranges from 0.85-2.24 in males and 0.76-3.23 in females. The assay measures total human ApoB in the 5-5000 ng/ml range. Samples giving human ApoB levels above 5000 ng/ml should be diluted in diluent before use. A 1:20,000 to 1:80,000 dilution for normal human plasma is suggested for best results. 
 
Human ApoB will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, monoclonal anti-human ApoB primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the peroxidase conjugated secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human ApoB. Color development is proportional to the concentration of total ApoB antigen in the samples. All reagents and standards are provided in these ELISA kits.
1 kit8415mol-innov2021
HAPO-C1Apolipoprotein CI is one of the protein components of VLDL lipoprotein. The normal plasma concentration of Apo CI is 4-7 mg per 100 ml. Elevated levels of Apo CI may offer some protection from obesity and insulin-dependent diabetes. Some evidence exists that the Apo CI H2 gene is positively associated with late-onset Alzheimer's disease. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.2 mg4930mol-innov2021
HAPO-C2Apo CII activates lipoprotein lipase which then hydrolyzes VLDL triglyceride to form IDL (intermediate density lipoproteins). The concentration of Apo CII in normal plasma is 3-8 mg per 100 ml. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg4930mol-innov2021
HAPO-C3Apo CIII inhibits the activation of lipoprotein lipase by Apo CII. Reduced levels of Apo CIII result in higher fatty acid uptake from plasma triglycerides into adipose tissue. Thus, Apo CIII is a potential target for treatment of obesity and insulin resistance. The normal plasma concentration of Apo CIII is 8-15 mg per 100 ml. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.2 mg5525mol-innov2021
HAPOC3KTApolipoprotein C-III (ApoC3) is a 79 amino acid peptide synthesized in the liver and intestine and bound to the surface of triglyceride rich particles such as very low density lipoprotein and chylomicrons in plasma. ApoC3 controls the triglyceride composition of these particles by inhibiting lipoprotein lipase. ApoC3 loss-of-function mutations have been associated with markedly reduced levels of triglycerides and remnant cholesterol and a decrease in coronary-artery calcification, a surrogate marker for atherosclerosis. Therefore, ApoC3 is a potential new target for reducing residual cardiovascular risk. The sensitive quantitative measurement of total human ApoC3 antigen in plasma, serum, urine & other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The average concentration of ApoC3 in normal human plasma is 0.125 mg/ml. The assay measures total human ApoC3 in the 0.01-5 ng/ml range. Samples giving human ApoC3 levels above 5 ng/ml should be diluted in blocking buffer before use. A 1:200,000 to 1:1,000,000 dilution for normal human plasma is suggested for best results. Human ApoC3 will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with horseradish peroxidase conjugated streptavidin. TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human ApoC3. The amount of color development is proportional to the concentration of total ApoC3 antigen in the sample. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
HAPO-EApolipoprotein E serves as a ligand for low density receptors and participates in the transport and redistribution of cholesterol and other lipids. Other functions include immunoregulation and cell growth modulation and differentiation. Apo E is thought to be involved in tissue repair as increased amounts of the protein are found at sites of peripheral nerve injury and regeneration. A mutant form is associated with familial type III hyperlipoproteinemia. The concentration of Apo E in normal plasma is 5 mg per 100 ml. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.05 mg4590mol-innov2021
HAPOEKTApolipoprotein E (ApoE) is a 34kDa 299 amino acid single chain plasma glycoprotein with three allelic isoforms that differ by a single amino acid. ApoE mediates the binding of very low density lipoproteins, high density lipoproteins, and chylomicrons to the low density lipoprotein (LDL) receptor, LDL receptor related protein, and heparan sulfate proteoglycans. Decreased serum ApoE levels are associated with higher risk of Alzheimer’s disease. The sensitive quantitative measurement of total human ApoE antigen in plasma and serum is easily performed with this 96 well strip format ELISA kit. ApoE in normal human serum ranges from 16-169 µg/ml with an average concentration of 47 µg/ml. The assay measures total human ApoE in the 0.2-20 ng/ml range. Samples giving human ApoE levels above 20 ng/ml should be diluted in diluent before use. A 1:100,000 to 1:200,000 dilution for normal human plasma is suggested for best results. 
 
Human ApoE will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated anti-human ApoE primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human ApoE. Color development is proportional to the concentration of total ApoE antigen in the samples. All reagents and standards are provided in these ELISA kits.
1 kit6885mol-innov2021
HAPO-HApolipoprotein H, also known as beta2Glycoprotein-1 (B2GP-1) is a plasma glycoprotein that circulates at a concentration of 200 ug/mL (4mM). B2GP-1 has been identified as a constituent of chylomicrons, very low density lipoproteins and high density lipoproteins in Human plasma. It has also been demonstrated to bind phospholipids, heparin and platelets where it can modulate the activity of adenylate (19percent). Although the precise function(s) are as yet unknown, B2GP-1 has been shown to interfere with blood coagulation by competitively binding to phospholipids exposed during cell activation or damage. Recent evidence also implicates B2GP-1 as a cofactor recognized by some anti-phospholipid antibodies present in autoimmune disorders such as systemic lupus erythematosus (SLE).0.1 mg4250mol-innov2021
HAPOTFTransferrin less the iron molecule. Like transferrin, apotransferrin has a physiological role in the transportation and distribution of iron among the body organs. It is also an important transport factor used in defined culture media. Purified to have less than 0.02 mg iron per gram of transferrin. Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+). Dissolves in water at 10 mg per ml. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Total protein determination by the Lowry method. >95percent pure and shows only one major band corresponding to the molecular weight of Transferrin by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.100 mg4165mol-innov2021
HASHFV-GFPolyclonal antibody (host horse).
IgG fraction purified by immobilized Protein A.
1.0 mg2975mol-innov2021
HATFAmino terminal fragment of human urokinase. The amino terminal fragment (ATF) of uPA is purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells. ATF contains the Kringle and Epidermal Growth Factor domains and is separated from LMW uPA by cleavage at the Lys135-Lys136 bond.0.1 mg7990mol-innov2021
HATIIIPrepared from fresh human plasma using several chromatographic steps.1.0 mg2720mol-innov2021
HATIII-IMay be used repeatedly. Protocol for purifying high affinity heparin with immobilized antithrombin:<br>
1. Equilibrate immobilized antithrombin in TBS (0.1M Tris-HCl, 0.15M NaCl, pH 7.4) or PBS (0.05M Sodium Phosphate, 0.15M NaCl, pH 7.4).<br>
2. Apply heparin in TBS or PBS. Binding capacity is ~0.1 mg high affinity heparin / ml resin and must be determined by the end user.<br>
3. Wash and elute heparin with 3M NaCl in TBS or PBS.<br>
4. Re-equilabrate resin in TBS or PBS.<br>
5. Add 0.02percent Sodium Azide for storage.
1.0 ml5100mol-innov2021
HATIIIKT-TOTAntithrombin III is a glycosylated plasma serine protease inhibitor that forms a stoichiometric complex with coagulation cascade enzymes. Antithrombin III inhibits alpha-Thrombin as well as Factor Xa, IXa, XIa and XIIa with heparin enhanced kinetics. Type 1 Antithrombin deficiency is characterized by decreased plasma antigen levels of antithrombin III. The sensitive quantitative measurement of total human antithrombin III antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. An antithrombin concentration of 137 ug/ml in human reference plasma was determined by house testing at 1:100,000 and 1:200,000 dilutions. The assay measures total human antithrombin III in the 0.02-20 ng/ml range. Samples giving human antithrombin III levels above 20 ng/ml should be diluted in blocking buffer before use. A 1:100,000 to 1:400,000 dilution for plasma is suggested for best results. Human antithrombin III will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, polyclonal anti-human antithrombin III primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody, which is proportional to the total antithrombin III present in the samples, reacts with the secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of antithrombin III in the samples. A standard calibration curve is prepared using dilutions of purified antithrombin III and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Human Antithrombin III standard provided in this kit is calibrated against the WHO International Standard for Human Plasma Antithrombin (NIBSC Code 08/258).</strong>1 kit8415mol-innov2021
HB101HB101 strain chemically competent cells from Molecular Innovations are an all purpose reagent for general cloning, sub-cloning and plasmid isolation. For a transformation efficiency of at least 1x10<sup>6</sup> simply thaw a tube of cells on ice, add 1-5 ul of DNA, gently mix and incubate on ice for 2-5 minutes, then spread 50-100 ul onto a pre-warmed culture plate. For greater transformation efficiencies heat shock at 37C for 1 minute before plating, or heat shock at 42C for 30 seconds then add SOC media and shake at 225 rpm at 37C for 1 hour before plating. Conveniently supplied as a pack of 5 single use 0.2 ml aliquots.<br><br> 
Genotype: F<sup>-</sup> mcrB mrr hsdS20(r<sub>B</sub><sup>-</sup> m<sub>B</sub><sup>-</sup>) recA13 leuB6 ara-14 proA2 lacY1 galK2 xyl-5 mtl-1 rpsL20(Sm<sup>R</sup>) glnV44 &lambda;<sup>-</sup>
1.0 ml1700mol-innov2021
HBTHuman beta-thrombin is prepared from purified a-thrombin by limited proteolysis with TPCK-treated trypsin. Beta-thrombin is generated by cleavage of the B-chain at the Arg106-Tyr107 bond. Purity is assessed by SDS-PAGE and activity is assessed using a fibrinogen clotting assay.1.0 mg10285mol-innov2021
HC1INHHuman C1 Inhibitor (also known as plasma protease C1 inhibitor, C1 esterase inhibitor, C1-inhibiting factor, C1-INH, and C1INA) is a single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, plasmin, Factors XIa and XIIa. Present in plasma at 16-33 mg per 100 ml. C1 esterase inhibitor deficiency is a rare condition resulting in facial swelling and abdominal cramping. Usually the condition is hereditary, though it may also occur when the C1EI is non-functional. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg4335mol-innov2021
HC1INHKT-TOTPlasma protease C1 inhibitor (aka C1 esterase inhibitor or SerpinG1) is a single-chain, 478 amino acid glycoprotein that regulates classical complement activation and the contact activation or intrinsic coagulation pathway. This 105 kDa serine protease inhibitor has a C-terminal serpin domain with unique stabilizing disulfide bonds and highly glycosylated N-terminal domain. C1 inhibitor irreversibly inactivates C1r, C1s, MASP1, MASP2, plasma kallikrein, thrombin, plasmin, tPA, and Factors XIa and XIIa. Genetic deficiency in plasma C1 inhibitor results in Type I hereditary angioedema. The sensitive quantitative measurement of total human C1 inhibitor in human plasma and serum is easily performed with this 96 well strip format ELISA kit. The normal human plasma concentration of C1 inhibitor is 0.2 mg/ml. The assay measures human C1 inhibitor in the 1-500 ng/ml range. Samples giving human C1 inhibitor levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:10,000-1:40,0000 dilution for plasma is suggested for best results. Human C1 inhibitor will bind to the affinity purified capture antibody coated on the microtiter plate. Free and complexed C1 inhibitor will bind to the plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human C1 inhibitor antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human C1 inhibitor. Color development is directly proportional to the concentration of total C1 inhibitor in the samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
HC3KTComplement Component 3 (C3), the most abundant serum complement component, is a disulfide-linked 185kDa 1,637 amino acid glycoprotein which supports the classical, alternative, and lectin pathways of complement activation. C3 is proteolytically activated by C3-convertase to the anaphylatoxin C3a and the opsonizing agent C3b. Serum concentrations of C3 are increased during acute and chronic inflammation such as rheumatoid arthritis, and are decreased due to increased consumption or autoimmune disorders such as systemic lupus erythematosus. The sensitive quantitative measurement of total human C3 antigen in plasma, serum, urine, milk, saliva and cell culture samples is easily performed with this 96 well strip format ELISA kit. C3 in normal human plasma ranges from 0.9-1.9 mg/ml with an average concentration of 1.39 mg/ml. The assay measures total human C3 in the 0.02-10 ng/ml range. Samples giving human C3 levels above 10 ng/ml should be diluted in blocking buffer before use. For best results, dilute plasma and serum samples 1:100,000 to 1:1,000,000, saliva samples to 1:100, urine samples 1:2 to 1:10, and milk samples 1:1,000 to 1:10,000. Human C3 will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human C3 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of C3 in the samples. A standard calibration curve is prepared using dilutions of purified C3and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>1 kit5185mol-innov2021
HCBCathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis. Activity: greater than 200 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of Z-Arg-Arg-beta-naphthylamide per minute at 40oC, using 100 mM Na/K phosphate, pH 6.0, with 1.33 mM EDTA and 2 mM DTT as the activation buffer. Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.025 mg4930mol-innov2021
HCDCathepsin D is an estrogen-regulated protein associated with tissue breakdown. Levels of cathepsin D have been positively correlated with recurring breast cancers of both node-negative and node-positive types. Additionally cathepsin D has been associated with amyloid formation in Alzheimer's plaques. As cathepsin D activity is increased by cigarette smoke, the enzyme may contribute to lung tissue damage in smokers. Activity: >=300 units per mg protein. One unit is defined as the amount of enzyme that digests hemoglobin-releasing peptides which are soluble in 10percent TCA. The reaction is measured by an increase of an A 280 of 1.0 per 60 minutes at 37oC . Substrate: acid denatured hemoglobin, pH 1.8 (0.2percent in reaction mixture). Buffer: 100 mM formate, pH 3.3. Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water to original volume, aliquot and freeze unused portion.0.025 mg4165mol-innov2021
HCGCathepsin G is a serine protease purified from neutrophils that has
multiple functions in the inflammatory process.  Applications include
substrate cleavage and inhibitor screening.
0.5 mg4845mol-innov2021
HCHA more basic protein than Cathepsin B or L. Functions as both an aminopeptidase and endopeptidase. Cathepsin H, like cathepsin L and B, is involved in the catabolism of proteins in the lysosomal system. Activity: greater than 1 unit per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of L-arginine-beta-napthylamide per minute at 40oC using 75 mM potasium phosphate, pH 6.8, with 1 mM EDTA and 3 mM cysteine as the activation buffer.  Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.025 mg4505mol-innov2021
HCLThe most powerful of the lysosomal proteases. It has a higher specific activity than cathepsin B and H in the degradation of a variety of physiological protein substrates. The level of cathepsin L is a strong predictor of relapse and survival following treatment of a primary breast tumor. Activity: Greater than 1 unit per mg of protein. One unit is defined as the amount of enzyme that hydrolyzes one micromole of Z-Phe-Arg-AFC per minute at 25oC using 400 mM Na Acetate, pH 5.5 with 4 mM EDTA and 8 mM DTT as the activation buffer in the presence of Brij.  Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.025 mg5355mol-innov2021
HCPAn acute-phase reactant. Increased levels are associated with normal pregnancy, rheumatoid arthritis, and cirrhosis. Decreased levels are associated with hepatolenticular degeneration (Wilson's Disease). An elevated level of Cp is found in patients with progressive tumors. Additionally, as Cp is a prooxidant, an elevated level is a sign of cardiovascular disease. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg4165mol-innov2021
HCPKTCeruloplasmin (aka Ferroxidase I) is a 132kDa 1,046 amino acid glycoprotein which carries 95% of serum copper by binding 6 cupric ions per molecule. Levels are decreased in Wilson’s Disease (hepatolenticular degeneration) and heritable aceruloplasminemia leading to iron accumulation in the liver or brain from impaired iron homeostasis. The sensitive quantitative measurement of human ceruloplasmin in plasma, serum, urine, milk, saliva and cell culture samples is easily performed with this 96 well strip format ELISA kit. The concentration of ceruloplasmin in normal human plasma is 0.3 mg/ml. The assay measures human ceruloplasmin in the 1-1,000 ng/ml range. Samples giving human ceruloplasmin levels above 1000 ng/ml should be diluted in blocking buffer before use. For best results, dilute plasma and serum samples 1:10,000 to 1:50,000 and milk samples 1:10 to 1:50. Saliva and urine samples should be applied directly to the plate for best results. Human ceruloplasmin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human ceruloplasmin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of ceruloplasmin in the samples. A standard calibration curve is prepared using dilutions of purified ceruloplasmin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5185mol-innov2021
HCSTCCystatin C (CST3, Cystatin-3, Gamma-Trace, Neuroendocrine Basic Polypeptide, Post-Gamma-Globulin, Post G-Globulin) is a small molecular weight peptide that is a potent inhibitor of many cysteine proteinases. Because of its small size it is freely filtered by the glomerulus and metabolized after tubular reabsorption. Serum levels of Cystatin C are a more precise test of kidney function than serum creatinine levels. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid deposition, such as Creutzfeldt-Jakob disease and Alzheimer’s disease. Human Cystatin C from Molecular Innovations is recombinantly produced in insect cell culture and purified by conventional and chelated metal affinity chromatography. Contains a 10X-Histidine tag at the C terminus for purification. It runs as a single band and is >95percent pure by SDS-PAGE. Inhibits activity of the cysteine proteinase papain using the substrate Pyr-Phe-Leu-pNA.0.01 mg3315mol-innov2021
HCTIncreased values of this enzyme and/or its zymogen have been found in patients with cystic fibrosis. Activity: 40-70 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of Suc-Ala-Ala-Pro-Phe-pNA per minute at 25C, pH 8.0.  Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg4165mol-innov2021
HECComposed of four identical subunits each with a molecular weight of 58,000. Catalyzes the reaction 2H2O2 to H2O+O2. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian cells, and together may function as a somatic oxidant defense. Prepared from whole blood shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg4590mol-innov2021
HFBNPrepared from fresh human plasma. Ideal reagent for tissue culture studies and protein-protein interactions. Thaw the fibronectin by placing the vial in a 37 C water bath and leaving it undisturbed until completely thawed. Do not disturb the vial at any time during the thawing process. If the vial is disturbed or removed prior to complete thawing, the fibronectin will form a gel and be unusable. Mix very gently with pipette after thawing. Vortexing, excessive agitation, repeated freezing and thawing of  fibronectin are not recommended.1.0 mg3060mol-innov2021
HFIBKTFibrinogen is a soluble glycoprotein that circulates in the blood and is converted to insoluble fibrin by thrombin in the final step of the coagulation cascade. Hepatic expression of fibrinogen increases two to four hundred fold during the acute phase response to infection or inflammation. Elevated fibrinogen levels are correlated with cardiovascular disease and atherosclerosis. The sensitive quantitative measurement of total human fibrinogen antigen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. The concentration of fibrinogen in normal human plasma ranges from 1.5 to 4.5 mg/ml. The assay measures total human fibrinogen in the 3.125-800 ng/ml range. Samples giving human fibrinogen levels above 800 ng/ml should be diluted in 1X diluent before use. A 1:100,000 to 1:1,000,000 dilution for plasma or a 1:100 dilution for serum is suggested for best results. Human fibrinogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human fibrinogen primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of fibrinogen in the samples. A standard calibration curve is prepared using dilutions of purified fibrinogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Human-Fibrinogen-Antigen-Capture-Plate>Human Fibrinogen Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Avidin-HRP-Labeled>Avidin-HRP</a>
1 Kit5015mol-innov2021
HFIB-TOT-PLATE96 well plate with 8 removable strips coated with affinity purified polyclonal antibody to human Fibrinogen at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of human fibrinogen antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
HFIIHuman prothrombin is prepared from fresh frozen human plasma. Human Prothrombin is a glycoprotein of molecular weight 72,000, and consists of a single polypeptide chain. Activation of Prothrombin by Factor Va, Xa and phospholipids yields the serine protease Thrombin. Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.9.0 mg3995mol-innov2021
HFIIITissue Factor, also known as coagulation Factor III or Thromboplastin, is a cell surface glycoprotein that binds Factor VII. The Tissue Factor / Factor VIIa complex initiates the extrinsic pathway of the coagulation cascade following vessel injury. The extra-cellular domain (amino acids 33-251) is expressed recombinantly with an N-terminal 6X-His tag in E. coli. Purified by chromatography then sterile filtered. >95percent pure by SDS-PAGE.0.025 mg7480mol-innov2021
HFIXHuman factor IX is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography. This protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.  Activity is determined via clotting assay.  Human Factor IX, activated by either the Contact or Tissue Factor Pathway, is responsible for the activation of Factor X to Xa.0.5 mg5525mol-innov2021
HFIXAHuman Factor IXa is prepared from Human Factor IX by activation with Bovine Factor XIa. This Bovine Factor XIa is removed after activation. Complete activation is observed by SDS-PAGE. The Factor XIa activates Factor IX in a two-step reaction. In the first step, an internal Arg-Ala bond is cleaved, and in the second step, an Arg-Val bond is cleaved. The second cleavage leads to the liberation of an activation peptide from the NH2-terminal portion of the heavy chain to produce Factor IXa-beta. Factor IXa-alpha has only the second cleavage at the Arg-Val bond with about half the coagulant activity of Human Factor IXa-beta. Complete activation is observed by SDS-PAGE. This protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Thaw rapidly in a 37C water bath without allowing protein to warm to 37C and immediately cool on ice.0.5 mg7480mol-innov2021
HFIXA-FL-INFPRPurified Human Factor IXa is active site labeled by incubation with Fluorescein-Phe-Pro-Arg-CMK (FL-INFPR). Excess dye is removed by dialysis.0.1 mg5780mol-innov2021
HFIXKT-TOTFactor IX (aka Christmas Factor) is a single-chain, 415 amino acid glycoprotein zymogen. Factor IX is activated by either Factor XIa or the Factor VIIa complex. Factor IXa converts Factor X to Factor Xa during the intrinsic pathway of the coagulation cascade. Factor IX is used to treat patients with hemophilia B, an X-linked
bleeding disorder. The sensitive quantitative measurement of total human Factor IX antigen in plasma samples is easily performed with this 96 well strip format ELISA kit.  <b>Factor IX and IXa will be detected by the assay.</b> The concentration of Factor IX in normal human plasma is about 5 ug/ml. The assay measures total human Factor IX in the 0.1-100 ng/ml range. Samples giving human Factor IX levels above 100 ng/m should be diluted in blocking buffer before use. A 1:500 to 1:1,000 dilution for plasma is suggested for best results. Human Factor IX will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human Factor IX primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor IX in the samples. A standard calibration curve is prepared using dilutions of purified Factor IX and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Human Factor IX standard provided in this kit is calibrated against the WHO International Standard for Human Plasma Factors II, VII, IX, X (NIBSC Code 09/172).</strong>
1 kit5525mol-innov2021
HFVHuman factor V is prepared from fresh frozen human plasma using immunoaffinity chromatography. Purity is determined by SDS-PAGE analysis and activity is measured in a factor V clotting assay.0.05 mg6460mol-innov2021
HFVAFactor Va is prepared by activating purified factor V with thrombin and is subsequently purified by immunoaffinity chromatography. This process results in cofactor preparations which are free of both activation peptides and thrombin. Purity is determined by SDS-PAGE analysis and activity is measured in a factor Va clotting assay.0.05 mg6460mol-innov2021
HFVIIHuman factor VII is purified using a combination of conventional techniques and immunoaffinity chromatography. Human Factor VII is a single-chain vitamin K dependent glycoprotein found in trace quantities in plasma (0.5 mg/Liter). In the Tissue Factor Pathway of coagulation, Human Factor Vlla, in the presence of calcium ions and tissue factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa. Purity is determined by SDS-PAGE analysis and activity is measured in a factor VII clotting assay.0.1 mg4675mol-innov2021
HFVIIAPrepared from purified Human Factor VII using Human Factor XIIa. The Factor Xlla is removed using affinity chromatography. Purity is determined by SDS-PAGE. Human Factor VIIa reduces to 29,500 and 23,500 with the addition of 2-mercaptoethanol. Activity is determined via clotting assay.  Factor Vlla, in the presence of calcium ions and Tissue factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa.0.1 mg5525mol-innov2021
HFVIIIKT-TOTFactor VIII (aka Factor VIII:C or Antihemophilic Globulin) is a glycoprotein zymogen that circulates in a stabilized non-covalent complex with von Willebrand Factor (vWF). Following activation by thrombin or Factor Xa, Factor VIIIa dissociates from vWF and catalyzes the activation of Factor X by Factor IXa in the amplification phase of coagulation. Factor VIIIa activity is quickly decreased by spontaneous dissociation and proteolytic degradation by activated Protein C, Factor Xa and Factor IXa. Hemophilia A is caused by mutations in the Factor VIII gene; a majority of patients have decreased Factor VIII plasma levels while 5% of patients have normal levels of nonfunctioning protein. The sensitive quantitative measurement of total human Factor VIII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The average normal plasma level of Factor VIII is defined as 1.0 IU/ml and the normal range is 0.4-1.8 IU/ml. Hemaophilia A patients are classified by the following Factor VIII levels: 0.05-0.25 IU/ml = mild, 0.01-0.05 IU/ml = moderate, and <0.01 IU/ml = severe. The assay measures total human Factor VIII in the 0.0016-0.84 IU/ml range. Samples giving human Factor VIII levels above 0.84 IU/ml should be diluted in blocking buffer before use. 1:8 and 1:16 dilutions for normal plasma, or 1:4 and 1:8 dilutions for Haemophiliac plasma, are suggested for best results.<br><br>Human Factor VIII will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human Factor VIII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human plasma. Color development is proportional to the concentration of Factor VIII in the samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Factor VIII level in the human plasma standard provided is calibrated against a secondary standard that is referenced to the WHO or ISTH International Standard.</strong>1 kit8415mol-innov2021
HFVIIKT-TOTFactor VII is a single chain glycoprotein zymogen that initiates the extrinsic coagulation pathway by forming a complex with exposed Tissue Factor 
and Ca2+. Factor VII in complex is rapidly cleaved to VIIa which activates Factor X and IX. Congenital Factor VII deficiency is rare and caused by heterogeneous decreased activity or antigen levels. Elevated Factor VII is associated with increased risk of coronary heart disease. The sensitive quantitative measurement of total human Factor VII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor VII, VIIa, and VII in complex with Tissue Factor will be detected by the assay.</b> The concentration of Factor VII in normal human plasma is 470 ng/ml. The assay measures total human Factor VII in the 0.2-100 ng/ml range. Samples giving human Factor VII levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:20-1:100 dilution for plasma is suggested for best results. Human Factor VII will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human Factor VII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor VII in the samples. A standard calibration curve is prepared using dilutions of purified Factor VII and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Human Factor VII standard provided in this kit is calibrated against the WHO International Standard for Human Plasma Factors II, VII, IX, X (NIBSC Code 09/172).</strong>
1 kit8415mol-innov2021
HFVKT-TOTFactor V (aka proaccelerin or labile factor) is a 2224 amino acid single chain glycoprotein. Factor V is activated to Factor Va by thrombin. Factor Va binds to Factor Xa and acts as a cofactor in accelerating the activation of prothrombin to thrombin. A genetic Factor V R506Q mutation has been shown to result in a resistance to activated protein C leading to venous thrombosis. The sensitive quantitative measurement of total human Factor V antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor V and Va will be detected by the assay.</b> The concentration of Factor V in normal human plasma ranges from 4-14 ug/ml. The assay measures total human Factor V in the 0.938-60 ng/ml range. Samples giving human Factor V levels above 60 ng/ml should be diluted in blocking buffer before use. A 1:800 dilution for plasma is suggested for best results. Human Factor V will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human Factor V primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor V in the samples. A standard calibration curve is prepared using dilutions of purified Factor V and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
HFXHuman factor X is isolated from fresh frozen human plasma by a combination of conventional techniques and immunoaffinity chromatography. In addition to the standard human factor X preparation, Gla-domainless human factor X is also available. Purity is determined by SDS-PAGE analysis and activity is measured in a factor X clotting assay.0.5 mg5525mol-innov2021
HFXAFactor Xa is prepared by activating purified Factor X with the Factor X activator isolated from Russell's viper venom. Cleavage occurs at the Arg51-Ile52 bond and releases an activation peptide. Factor Xa is purified from the activation mixture by chromatography over benzamidine-Sepharose. Purity is determined by SDS-PAGE analysis and activity is measured in a Factor Xa clotting assay and/or chromogenic substrate assay.0.5 mg6630mol-innov2021
HFXA-BFactor Xa-beta is prepared by autoproteolysis of purified Factor Xa in the presence of calcium and phospholipid followed by chromatography over immobilized benzamidine. Cleavage occurs at the Arg290-Gly291 peptide bond. Purity is determined by SDS-PAGE analysis and activity is measured in a Factor Xa clotting assay and/or chromogenic substrate assay.0.5 mg9265mol-innov2021
HFXA-BIOPurified Human Factor Xa is active site labeled by incubation with biotinylated-Glu-Gly-Arg-CMK (GGACK-BIO). Excess inhibitor is removed by dialysis.0.1 mg6120mol-innov2021
HFXIHuman Factor XI is a two-chain glycoprotein prepared from fresh human plasma using several chromatographic steps. The two chains are identical disulfide bonded polypeptides with molecular weights of 80,000 daltons.  Factor XI is activated to Factor XIa by Factor Xlla. Purity of Factor XI is >95percent by SDS-PAGE and activity is determined via clotting assay. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.1 mg3825mol-innov2021
HFXIAHuman Factor XIa is prepared from Human Factor XI using Human Factor Xlla. Factor Xlla is removed using a corn trypsin inhibitor column. Factor XI is activated to Factor XIa by Factor Xlla and High Molecular Weight Kininogen in the contact pathway of the coagulation cascade. FXI undergoes proteolytic cleavage in which the 80,000 chain reportedly is cleaved to a heavy and light chain with molecular weights of about 48,000 and 33,000. Factor XIa is responsible for the activation of Factor IX to Factor IXa. Unlike other examples of activation of Vitamin K-dependent blood-clotting proteins, Factor XIa proteolysis of Factor IX does not require membrane surfaces. Complete activation and >95percent purity is observed by SDS-PAGE. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.1 mg4675mol-innov2021
HFXIIHuman Factor XII is a single chain glycoprotein prepared from fresh human plasma by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease (Factor alpha-Xlla) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation.  Purity of Factor XII is >95percent by SDS-PAGE and activity is determined via clotting assay. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.5 mg5525mol-innov2021
HFXIIAHuman Factor alpha-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system. Human Factor XII and prekallikrein are thought to be involved in a reciprocal activation mechanism in which Factor XIIa activates prekallikrein to kallikrein, which in turn converts Factor XII to XIIa. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. Human Factor alpha-XIIa is activated from homogeneous Human Factor XII by an autoactivation process with Dextran Sulfate followed by repurification to isolate Factor alpha-XIIa and Factor beta-XIIa (Cat # <a href=http://www.mol-innov。。com/item/Human-coagulation-Factor-beta-XIIa>HFXIIAB</a>). Complete activation is observed on SDS-PAGE. Factor XIIa is >95percent pure by SDS-PAGE and activity is determined via clotting assay. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.5 mg6460mol-innov2021
HFXIIABHuman Factor beta-XIIa is generated in vivo by kallikrein cleavage of Factor alpha-XIIa and contains the catalytic light chain and the C-terminal peptide of the heavy chain of Factor alpha-XIIa. Human Factor beta-XIIa is activated from homogeneous Human Factor XII by an autoactivation process with Dextran Sulfate followed by repurification to isolate Factor alpha-XIIa (Cat # <a href=http://www.mol-innov。。com/item/Human-coagulation-Factor-alpha-XIIa>HFXIIA</a>) and Factor beta-XIIa. Complete activation is observed on SDS-PAGE. Factor XIIa is >95percent pure by SDS-PAGE and activity is determined via clotting assay. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.1 mg3740mol-innov2021
HFXIIAB-BIOHuman Factor beta-XIIa is activated from homogeneous Human Factor XII by an autoactivation process with Dextran Sulfate followed by repurification and biotinylation on lysine residues. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.05 mg8840mol-innov2021
HFXIIAB-INSThe low molecular weight beta form of human Factor XIIa is generated <i>in vivo</i> by kallikrein cleavage of Factor alpha-XIIa and contains the catalytic light chain and the C-terminal peptide of the heavy chain of Factor alpha-XIIa. Recombinant Human Factor beta-XIIa is activated from insect cell culture derived Factor XII by an extended autoactivation process with Dextran Sulfate followed by repurification. Complete activation is observed on SDS-PAGE. Factor XIIa activates Factor XI to XIa thereby triggering the Contact Factor cascade. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Specific activity of this recombinant product is typically lower than that of plasma derived material. Custom mutants of Factor XII are also available, please contact us for more details.0.05 mg5695mol-innov2021
HFXIIIHuman Factor XIII is a tetramer composed of two pairs of chains held together by noncovalent bonds. After activation of the zymogen via Thrombin to its active enzyme form, Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.0.25 mg6715mol-innov2021
HFXIIIAHuman Factor XIIIa is activated from Factor XIII by cleavage with human alpha thrombin. The thrombin is subsequently removed via chromatography. Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.0.25 mg7650mol-innov2021
HFXIIKT-TOTFactor XII (aka Hageman Factor) is a single-chain, 615 amino acid glycoprotein zymogen. Factor XII is activated by kallikrein. Factor XIIa converts prekallikrein to kallikrein during the intrinsic pathway of the coagulation cascade. Although Factor XII is not thought to play an essential role in normal hemostasis, lack of Factor XII in a mouse model resulted in a severe defect in thrombus formation. The sensitive quantitative measurement of total human Factor XII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor XII and XIIa will be detected by the assay.</b> The concentration of Factor XII in normal human plasma ranges from 15-47 ug/ml. The assay measures total human Factor XII in the 0.1-100 ng/ml range. Samples giving human Factor XII levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000 to 1:5,000 dilution for plasma is suggested for best results. Human Factor XII will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human Factor XII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor XII in the samples. A standard calibration curve is prepared using dilutions of purified Factor XII and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit4845mol-innov2021
HFXIKT-TOTFactor XI is a disulfide linked two-chain glycoprotein zymogen and is the precursor of the coagulation enzyme Factor XIa. Factor XI consists of two identical monomers and circulates in plasma in complex with kininogen. Factor XI is activated by Factor XIIa and converts Factor IX to Factor IXa during the intrinsic pathway of the coagulation cascade. The sensitive quantitative measurement of total human Factor XI antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor XI and XIa will be detected by the assay.</b> The concentration of Factor XI in normal human plasma ranges from 3-6 ug/ml. The assay measures total human Factor XI in the 0.2-100 ng/ml range. Samples giving human Factor XI levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000 dilution for plasma is suggested for best results. Human Factor XI will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human Factor XI primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor XI in the samples. A standard calibration curve is prepared using dilutions of purified Factor XI and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Human Factor XI standard provided in this kit is calibrated against the WHO International Standard for Human Plasma Factor XI (NIBSC Code 04/102).</strong>1 kit8415mol-innov2021
HFXKT-TOTFactor X is a disulfide linked two-chain glycoprotein zymogen and is the precursor of the coagulation enzyme Factor Xa. Factor X is activated by Factor IXa in complex with Factor VIII, calcium and phospholipids during the intrinsic pathway and by Factor VIIa in complex with Tissue Factor, calcium and phospholipids during the extrinsic pathway of the coagulation cascade. The sensitive quantitative measurement of total human Factor X antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor X, Xa, and Xa in complex with inhibitors or cofactors will be detected by the assay.</b> The concentration of Factor X in normal human plasma is 7-8 ug/ml. The assay measures total human Factor X in the 0.1-50 ng/ml range. Samples giving human Factor X levels above 50 ng/ml should be diluted in blocking buffer before use. A 1:1,000 dilution for plasma is suggested for best results. Human Factor X will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human Factor X primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of Factor X in the samples. A standard calibration curve is prepared using dilutions of purified Factor X and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
HGCGGC globulin, also known as Vitamin D-binding protein (DBP/VDB), Vitamin D-binding protein-macrophage activating factor (DBP-MAF), and Gc protein-derived macrophage activating factor (Gc-MAF), is an alpha 2 glycoprotein composed of a single polypeptide chain and present in plasma at levels of 20-55 mg/100 ml. It functions in the binding and transport of vitamin D and may also play an important role in actin homeostatis since it has been shown to bind monomeric actin with high affinity. GC-globulin also binds membranes of both circulating B and T lymphocytes. Clinically, concentrations are reduced in patients with severe liver diseases. GC-globulin may also play an important role in the mechanism of the osteomalacia that occurs with Itai-Itai disease.  Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg4165mol-innov2021
HGPGPrepared from fresh human plasma by immobilized lysine chromatography.1.0 mg3060mol-innov2021
HGPG-FITCFITC labeled human Glu plasminogen prepared from human plasma.1.0 mg4080mol-innov2021
HGTA non-clotting derivative thrombin produced from Human alpha-Thrombin by controlled incubation with Trypsin-Sepharose. Gamma-thrombin is generated by cleavage of the B-chain at both the Arg106-Tyr107 and Lys190-Gly191 bonds. Gamma-thrombin is a noncoagulant form of thrombin that retains much of its platelet-activating capacity. Gamma-thrombin purity is determined by SDS-PAGE and protein concentration is determined by BCA assay.1.0 mg10285mol-innov2021
HHCIIHeparin Cofactor II is a single chain glycoprotein prepared from fresh frozen human plasma. HCII is a specific inhibitor of thrombin with increased activity in the presence of heparin. Heparin Cofactor II purity is determined by SDS-PAGE and the activity is measured by the ability to inhibit thrombin in the presence of saturating concentrations of heparin.0.1 mg7820mol-innov2021
HHDLHDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intravascular catabolism of lipoproteins. HDL levels are inversely correlated with coronary heart disease. In a normal fasting individual, HDL concentrations range from 1.0-2.0 g/L. Purity: single arc by IEP against antisera to whole human serum. Essentially free of other plasma lipoproteins as determined by electrophoresis using Fat Red 7B stain for lipids and Coomassie Blue for proteins. >95percent of total lipoprotein content by electrophoresis. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Do NOT freeze this product.5.0 mg6120mol-innov2021
HHPAn acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water to original volume, aliquot and freeze unused portion. Molecular Weights by phenotype - Hp 1-1: 86,000; Hp 2-1: 200,000; Hp 2-2: 400,000.5.0 mg4760mol-innov2021
HHP-11Haptoglobin is an acute phase plasma glycoprotein that binds free hemoglobin. Hemoglobin-haptoglobin complexes are removed by the macrophage CD163 receptor. Humans possess two major haptoglobin alleles that are inherited co-dominantly resulting in three possible phenotypes. Hp 1-1 is the most effective in binding free hemoglobin and circulates as dimers in serum. Purified from single donors screened by SDS-PAGE and western blot for the Hp 1-1 phenotype. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg5355mol-innov2021
HHP-22Haptoglobin is an acute phase plasma glycoprotein that binds free hemoglobin. Hemoglobin-haptoglobin complexes are removed by the macrophage CD163 receptor. Humans possess two major haptoglobin alleles that are inherited co-dominantly resulting in three possible phenotypes. Hp 2-2 is the least effective in binding free hemoglobin and circulates as a range of multimers in serum. Purified from single donors screened by SDS-PAGE and western blot for the Hp 2-2 phenotype. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg5355mol-innov2021
HHPXHemopexin is a single-chain protein belonging to the family of blood transport proteins. It binds to heme released into the bloodstream during the degradation process. Recent studies have demonstrated that hemopexin acts as an extracellular antioxidant against hemoglobin-mediated damage in inflammation. Hemopexin protects against heme toxicity and conserves and recycles iron. Abnormal levels of hemopexin are associated with hemolytic anemia, chronic neuromuscular disease, and acute intermittent porphyria. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg3400mol-innov2021
HHPXKTHemopexin (HPX aka beta-1B-glycoprotein) is a single chain, 439 amino acid 63 kDa glycoprotein that binds heme with the highest affinity of any known protein. The main function of HPX in the circulation is scavenging heme released by heme containing proteins such as hemoglobin. HPX removes harmful heme and other porphyrin groups to form the second line of defense, after haptoglobin, against hemoglobin-mediated oxidative damage during intravascular hemolysis. Plasma HPX levels can decrease upon injury and inflammation by LRP/CD91-mediated endocytosis of HPX-heme complexes by hepatocytes and macrophages. 
 
The sensitive quantitative measurement of human HPX in plasma and serum is easily performed with this 96 well strip format ELISA kit. The normal human plasma concentration of HPX is 0.4-1.5 mg/ml. The assay measures human HPX in the 0.1-100 ng/ml range. Samples giving human HPX levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000-1:4,000,0000 dilution for plasma or serum is suggested for best results. Human HPX will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human HPX primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of human HPX in the samples. A standard calibration curve is prepared using dilutions of purified HPX and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.
1 kit5950mol-innov2021
HK-HMWHMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a nonenzymatic cofactor of the contact activation system of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogen links prekallikrein to a negatively charged surface thereby allowing activation to kallikrein by surface bound Factor alpha-Xlla. Kininogen also forms a complex with Factor XI and accelerates its activation to XIa by alpha-Xlla. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease. >95percent pure by SDS-PAGE and >95percent single chain. Prepared from plasma found negative by FDA accepted
methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).
1.0 mg5185mol-innov2021
HK-LMWLMW Kininogn is involved in blood pressure regulation since it is an endogenous protein substrate for tissue kallikrein. Proteolytic cleavage by kallikrein releases vasoactive bradykinin from LMW kininogen. In addition, LMW kininogen, like HMW kininogen, is a major extracellular cysteine protease inhibitor. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg4165mol-innov2021
HKNGKT-TOTHigh molecular weight kininogen (HK, aka Fitzgerald Factor) is the single chain 626 amino acid 120kDa glycoprotein precursor of the vasoactive peptide bradykinin. Kininogen is an important cofactor for the activation of zymogens prekallikrein, Factor XII, and Factor XI in the contact activation or intrinsic coagulation pathway. Additionally kininogen is a major inhibitor of systemic cysteine proteinases such cathepsins, calpain and papain. The sensitive quantitative measurement of total human kininogen antigen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. The concentration of prekallirein in normal human plasma is 65-115 ug/ml with an average concentration of 83 ug/ml. The assay measures human kininogen in the 0.1-100 ng/ml range. Samples giving human kininogen levels above 100 ug/ml should be diluted in blocking buffer before use. A 1:10,000-1:50,000 dilution for plasma is suggested for best results. Human kininogen will bind to the monoclonal capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated anti-human kininogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of kininogen in the samples. A standard calibration curve is prepared using dilutions of purified kininogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5185mol-innov2021
HK-TCHMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a nonenzymatic cofactor of the contact activation system of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogen links prekallikrein to a negatively charged surface thereby allowing activation to kallikrein by surface bound Factor alpha-Xlla. Kininogen also forms a complex with Factor XI and accelerates its activation to XIa by alpha-Xlla. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease. The two chain form is prepared by kallikrein digestion of single chain kininogen. Two chain kininogen repurified to remove traces of kallikrein and is kinin free. >95percent pure by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted
methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).
1.0 mg4335mol-innov2021
HLDLIn a normal fasting individual, low density lipoprotein concentrations range from 2.0 - 3.5 g/L. LDL constitutes 50percent of the total lipoprotein mass in plasma and is the major carrier of cholesterol and cholesteryl esters. LDL levels strongly correlate with coronary heart disease. Purity: single arc by IEP against antisera to whole human serum. Essentially free of other plasma lipoproteins as determined by electrophoresis using Fat Red 7B stain for lipids and Coomassie Blue for proteins. >95percent of total lipoprotein content by electrophoresis. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Do NOT freeze this product.5.0 mg6120mol-innov2021
HLPLA2Lipoprotein-associated phospholipase A2, also known as platelet-activating factor acetylhydrolase, is a secreted enzyme which catalyzes the degradation of platelet-activating factor to biologically inactive products. This  enzyme is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. In the blood it is mainly associated with LDL and less than 20% is coupled to HDL. Expressed recombinantly with an N-terminal 8X-His tag and purified by chromatography. >95percent pure by SDS-PAGE.0.005 mg5270mol-innov2021
HLRP-C2-FCLow density lipoprotein receptor-related protein 1 (LRP1, LRP-1), also known as alpha-2-macroglobulin receptor (A2MR), cluster of differentiation 91 (CD91), and apolipoprotein E receptor (APOER), is a plasma membrane receptor protein that is expressed as a non-covalently associated 515 kDa alpha chain and 85 kDa beta chain. LRP-1 binds a wide variety of targets, is involved in a number of cell signaling and clearance events, and is clinically implicated in cardiovascular disease, cancer, and Alzheimer's disease. Human LRP1 Cluster II (Arg786-Leu1165) is located on the alpha chain and contains 8 cysteine rich ligand binding domains known as LDL receptor type A repeats (LDLa). Expressed recombinantly as a fusion protein with a C-terminal IEGRMD linking sequence and Fc tag, purified by chromatography, sterile filtered and lyophilized. &gt;95percent pure by SDS-PAGE and binds with high affinity to receptor associated protein (RAP) with a kD of &lt;2nM as determined by Biacore surface plasmon resonance analysis. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.<br> 
References<br> 
Dudley K. Strickland, Dianaly T. Au, Patricia Cunfer, and Selen C. Muratoglu. Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity. Arteriosclerosis, Thrombosis, and Vascular Biology 2014, 34:487–498.
0.05 mg5015mol-innov2021
HLRP-C3-FCLow density lipoprotein receptor-related protein 1 (LRP1, LRP-1), also known as alpha-2-macroglobulin receptor (A2MR), cluster of differentiation 91 (CD91), and apolipoprotein E receptor (APOER), is a plasma membrane receptor protein that is expressed as a non-covalently associated 515 kDa alpha chain and 85 kDa beta chain. LRP-1 binds a wide variety of targets, is involved in a number of cell signaling and clearance events, and is clinically implicated in cardiovascular disease, cancer, and Alzheimer's disease. Human LRP1 Cluster III (Ser2522-Ile2941) is located on the alpha chain and contains 10 cysteine rich ligand binding domains known as LDL receptor type A repeats (LDLa). Expressed recombinantly as a fusion protein with a C-terminal DIEGRMD linking sequence and Fc tag, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and binds with high affinity to receptor associated protein (RAP) with a kD of <3nM as determined by Biacore surface plasmon resonance analysis. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.<br> 
References<br> 
Dudley K. Strickland, Dianaly T. Au, Patricia Cunfer, and Selen C. Muratoglu. Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity. Arteriosclerosis, Thrombosis, and Vascular Biology 2014, 34:487–498.
0.05 mg5015mol-innov2021
HLRP-C4-FCLow density lipoprotein receptor-related protein 1 (LRP1, LRP-1), also known as alpha-2-macroglobulin receptor (A2MR), cluster of differentiation 91 (CD91), and apolipoprotein E receptor (APOER), is a plasma membrane receptor protein that is expressed as a non-covalently associated 515 kDa alpha chain and 85 kDa beta chain. LRP-1 binds a wide variety of targets, is involved in a number of cell signaling and clearance events, and is clinically implicated in cardiovascular disease, cancer, and Alzheimer’s disease. Human LRP1 Cluster IV (Ser3332-Asp3779) is located on the alpha chain and contains 11 cysteine rich ligand binding domains known as LDL receptor type A repeats (LDLa). Expressed recombinantly as a fusion protein with a C-terminal IEGRMD linking sequence and Fc tag, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and binds with high affinity to receptor associated protein (RAP) with a kD of <2nM as determined by Biacore surface plasmon resonance analysis. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.<br> 
References<br> 
Dudley K. Strickland, Dianaly T. Au, Patricia Cunfer, and Selen C. Muratoglu. Low-density lipoprotein receptor-related protein-1: role in the regulation of vascular integrity. Arteriosclerosis, Thrombosis, and Vascular Biology 2014, 34:487–498.
0.05 mg5015mol-innov2021
HLTFKTHuman lactoferrin (aka lactotransferrin or growth-inhibiting protein 12) is an 82.4kDa 691 amino acid glycoprotein which carries 2 ferric ions per molecule and is the main iron binding protein in milk. Lactoferrin has multiple physiological functions including iron absorption regulation and antibacterial, antiviral, and antiparasitic activity. Degranulated neutrophils are the primary source of plasma lactoferrin which is increased during inflammation and bacterial infection. The sensitive quantitative measurement of human lactoferrin in human plasma, serum, milk, and cell culture samples is easily performed with this 96 well strip format ELISA kit. The normal human concentration of lactoferrin is 100 ng/ml in plasma and 5.3 mg/ml in milk. The assay measures human lactoferrin in the 0.1-100 ng/ml range. Samples giving human lactoferrin levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:100-1:500 dilution for plasma or serum and and 1:200,000 dilution for breast milk is suggested for best results. Human lactoferrin will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated anti-human lactoferrin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared using dilutions of human lactoferrin and is measured along with the test samples. Color development is proportional to the concentration of total lactoferrin in the samples. All reagents and standards are provided in these ELISA kits.1 kit5950mol-innov2021
HMFBNPrepared from fresh hamster plasma. Ideal reagent for tissue culture studies and protein-protein interactions. Thaw the fibronectin by placing the vial in a 37 C water bath and leaving it undisturbed until completely thawed. Do not disturb the vial at any time during the thawing process. If the vial is disturbed or removed prior to complete thawing, the fibronectin will form a gel and be unusable. Mix very gently with pipette after thawing. Vortexing, excessive agitation, repeated freezing and thawing of  fibronectin are not recommended.1.0 mg6035mol-innov2021
HNE-LChromatographically purified from leucocytes of purulent human sputum and lyophilized. The lyophilized, salt-free, soluble powder is stable for over a year when stored at 5 C. The protein is greater than 95percent pure by SDS-PAGE and is free of cathepsin G, MPO and lysozyme. 800-900 units per mg of protein on the substrate Suc-Ala-Ala-Ala-pNA. 15000-19000 units per mg protein on the substrate MeO-Suc-Ala-Ala-Pro-Val-pNA. One unit will hydrolyze 1 nanomole of substrate per minute at pH 7.5 and 25 C. The following diluents and concentrations are recommended: 1) 1 mg/ml in 0.05 M Na Acetate pH 5.0 containing 0.1 M NaCl. Stable 7 days at 5 C (in ice). 2) 10 mg/ml in 50percent glycerol 50percent 0.02 M Na Acetate pH 5. Stable at least 60 days at -20 C with 20 cycles between -20 C and 5 C. 3) May be dissolved at 10 mg/ml in 2 mM HoAc and re-lyophilized in smaller quantities. Stability is better in acidic (pH 5.0) than basic buffers. Inactivation may occur at pH 8.0 due to autolysis and/or proteolysis by trypsin such as bovine pancreatic trypsin. Proteolysis can be inhibited by benzamidine. Autolysis and proteolysis can be inhibited by elastatinal. However, elastatinal is also an inhibitor of elastase. Low pH protects the elastase from both autolysis and proteolysis.0.5 mg9265mol-innov2021
HPAI-A335EFrom the laboratory of Professor Paul Declerck - Leuven BELGIUM. A single substitution at position P12 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. Reactive center loop insertion follows protease cleavage and the PAI-1 loses vitronectin binding properties. This molecule is useful for mechanistic studies.<br>
References<br>
1. Aertgeerts, K. et al. (1995) Proteins 23:118-121.<br>
2. Aertgeerts, K. et al. (1995) Nat. Struct. Biol. 2:891-897.<br>
3. Xue, Y. et al. (1998) Structure 6:627-636.
0.5 mg12155mol-innov2021
HPAI-AVIThis human PAI-1 variant contains a mutation at the active site to make it specific for inhibition of neutrophil elastase (R346V).  Additional mutations provide resistance to cleavage (V343A) and increased stability (I91L).  This preparation has low endotoxin (<20 EU/mg) so is suitable for in vivo studies.0.5 mg12155mol-innov2021
HPAI-I91LThis human PAI-1 mutant has a single point mutation (Isoleucine 91 to Leucine) that provides increased stability for use in long term binding experiments or in vivo studies. It is an excellent control for experiments involving the non-LRP binding stable mutant human PAI-1 (Catalog Number <a href=http://www.mol-innov。。com/item/PAI-1-mutant-stable-no-LRP-binding>HPAI-R76E-I91L</a>). The half life has not been quantified but is greater that wild type and less than the 14-1b stable mutant (Catalog Number <a href=http://www.mol-innov。。com/item/Human-PAI-1-stable-mutant-form>CPAI</a>).0.5 mg12155mol-innov2021
HPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active human PAI-1 in plasma samples is easily performed with this 96 well strip format ELISA kit. The PAI-1 concentration of normal platelet-free plasma is 21 ng/ml, platelet-rich plasma is 283 ng/ml and serum is 270 ng/ml. 1 PAI-1 unit = 1.34 ng. The assay measures active PAI-1 in the 0.125-100 U/ml range. Samples giving human PAI-1 levels above 100 U/ml should be diluted in PAI-1 depleted plasma before use. Normal plasma should be applied directly to the plate for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay. Validated in citrate, EDTA, and heparin plasma. Vitronectin does not interfere with the detection of active PAI-1. This kit does not cross react with mouse PAI-1.</b> After appropriate washing steps, anti human PAI-1 primary antibody binds to the PAI-1. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared in PAI-1 depleted plasma using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Human PAI-1 standard provided in this kit is calibrated against the WHO International Standard for Human PAI-1 (NIBSC Code 92/654).</strong><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br> 
The standard curve for this kit is generated using included PAI-1 depleted human plasma and is best suited for measurement of PAI-1 in plasma or serum. This kit is also available with a standard curve in BSA/TBS for researchers measuring PAI-1 in culture media or tissue extracts under <a href="http://www.mol-innov。。com/products/active-human-pai-1-functional-assay-elisa-kit-for-non-plasma-samples/" target="_blank"><span style="color: blue;">catalog number HPAIKT-NP</span></a>. 
<br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Urokinase-Coated-Plate>uPA Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a
1 Kit8075mol-innov2021
HPAIKT-NPPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active human PAI-1 in non-plasma samples including cell culture media or tissue extracts is easily performed with this 96 well strip format ELISA kit. The assay measures active PAI-1 in the 0.125-100 ng/ml range. Samples giving human PAI-1 levels above 100 ng/ml should be diluted in blocking buffer before use. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay. Vitronectin does not interfere with the detection of active PAI-1. This kit does not cross react with mouse PAI-1.</b> After appropriate washing steps, anti human PAI-1 primary antibody binds to the PAI-1. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br> 
This kit is also available with a standard curve in PAI-1 depleted human plasma for researchers measuring PAI-1 in plasma or serum samples under <a href="http://www.mol-innov。。com/products/active-human-pai-1-functional-assay-elisa-kit" target="_blank"><span style="color: blue;">catalog number HPAIKT</span></a>.
1 Kit8075mol-innov2021
HPAIKT-TOTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of total human PAI-1 antigen in plasma and other biological samples is easily performed with this 96 well strip format ELISA kit. The PAI-1 concentration of normal platelet-free plasma is 21 ng/ml, platelet-rich plasma is 283 ng/ml and serum is 270 ng/ml. The assay measures human PAI-1 in the 0.1-100 ng/ml range. Samples giving human PAI-1 levels above 100 ng/ml should be diluted in PAI-1 depleted plasma before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Human PAI-1 will bind to the capture antibody coated on the microtiter plate. <b>Free, latent, and complexed PAI-1 will be detected by the assay.</b> After appropriate washing steps, anti human PAI-1 primary antibody binds to the PAI-1. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br>Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Human-PAI-1-depleted-plasma-sodium-citrate>Human PAI-1 Depleted Plasma</a>1 Kit8075mol-innov2021
HPAI-P1NBDP1'-NBD PAI-1 was created by mutagenesis of the methionine residue (Met347) at the P1-P1' scissile bond to cysteine. This provides a free thiol group for labeling with NBD, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-NBD PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase.0.5 mg12155mol-innov2021
HPAI-P9NBDP9-NBD PAI-1 was created by mutagenesis of the P9 serine residue (Ser338) on the reactive center loop to cysteine. This provides a free thiol group for incorporation of N,N'-dimethyl-N-(acetyl)-N'-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) (NBD), a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P9-NBD PAI-1 is enhanced 6-7 fold upon insertion of the reactive center loop into beta-sheet A following complex formation with proteinases, formation of the latent species, or cleavage by elastase. The incorporated probe is excited at 480 nm and displays a broad emission spectrum with a peak centered 542 nm with a resultant blue-shift to 520 nm following reactive center loop insertion. The modified PAI-1 is nearly as active as wt PAI-1 and is more resistant to the spontaneous latency reaction making this an excellent tool for monitoring reaction rates of PAI-1 (1). P9-NBD PAI-1 has been utilized in a number of studies to determine the rates of loop insertion and SERPIN reaction mechanisms when reacted with various proteinases (1,2), inactivating antibodies (2) and conformational changes imposed by the binding of vitronectin (4).  
<br><br> 
<b>References</b>: <br> 
1. Shore JD, et al.(1995) J Biol Chem 270:5395-5398. <br> 
2. Lawrence D, et al.(2000) J Biol Chem 275:5839-5844. <br> 
3. Verhamme IM, et al.(1999) J Biol Chem 274:17511-17517.<br>  
4. Gibson A, et al.(1997) J Biol Chem 272:5112-5121.<br><br>
0.5 mg12155mol-innov2021
HPAI-Q123KA single mutation results in 10-fold loss of binding of the PAI-1 mutant to the important ligand vitronectin. All other aspects of PAI-1 biological activity such as anti-protease activity remain unaffected.<br>
References<br>
Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal. Jensen JK, Durand MK, Skeldal S, Dupont DM, Bødker JS, Wind T, Andreasen PA. FEBS Lett. 2004 Jan 2;556(1-3):175-9.<br>
Conservation of Critical Functional Domains in Murine Plasminogen Activator Inhibitor-1. Zhi Xu, Rashna D. Balsara, Natalia V. Gorlatova, Daniel A. Lawrence, Francis J. Castellino, and Victoria A. Ploplis. J. Biol. Chem., Apr 2004; 279:17914-20.
0.5 mg12155mol-innov2021
HPAI-QRA double mutation (Q123K and R101A) results in greatly reduced binding of the PAI-1 mutant to the important ligand vitronectin. All other aspects of PAI-1 biological activity such as anti-protease activity remain unaffected.<br>
References<br>
Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronectin but otherwise normal. Jensen JK, Durand MK, Skeldal S, Dupont DM, Bødker JS, Wind T, Andreasen PA. FEBS Lett. 2004 Jan 2;556(1-3):175-9.<br>
Conservation of Critical Functional Domains in Murine Plasminogen Activator Inhibitor-1. Zhi Xu, Rashna D. Balsara, Natalia V. Gorlatova, Daniel A. Lawrence, Francis J. Castellino, and Victoria A. Ploplis. J. Biol. Chem., Apr 2004; 279:17914-20.
0.5 mg12155mol-innov2021
HPAI-R76E-I91LA substitution of Glutamic Acid for Arginine at position 76 greatly decreases the binding of this Human PAI-1 mutant to the low density lipoprotein receptor-related protein (LRP). The putative LRP binding exosite is thought to overlap with the heparin binding site on the PAI-1 molecule. Binding to LRP or similar receptors leads to the clearance of PAI-1 complexes. An additional mutation (Isoleucine 91 to Leucine) provides increased stability for use in long term binding experiments or in vivo studies. A human PAI-1 point mutation stable form (Catalog Number <a href=http://www.mol-innov。。com/item/Human-PAI-1-point-mutation-stable-form>HPAI-I91L</a>) is available as an LRP binding control PAI-1.<br><br> 
<b>References</b>:<br> Stefansson S. et al. (1998) J Biol Chem 273:6358-6366.
0.5 mg12155mol-innov2021
HPAI-RRTwo amino acid substitutions at positions P12 and P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. The reactive center loop does not insert following protease cleavage and the PAI-1 retains normal vitronectin binding. The double mutation also results in extended half-life compared to native PAI-1. This molecule is useful for mechanistic studies.<br>
References<br>
1. Huang, Y. et al. (2009) Am. J. Physiol. Renal Physiol. 297:F1045–F1054.<br>
2. Courey, A.J. et al. (2011) Blood. 118:2313–2321.<br>
3. Zhong, J. et al. (2014) Lab. Invest. 94:633–644.
0.5 mg12155mol-innov2021
HPAI-T333RA single substitution at position P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. Reactive center loop insertion follows protease cleavage and the PAI-1 loses vitronectin binding properties. This molecule is useful for mechanistic studies.<br>
References<br>
1. Lawrence, D.A. et al. (2000) J. Biol. Chem. 275:5839-5844.<br>
2. Palmieri, D. et al. (2002) J. Biol. Chem. 277:40950-40957.
0.5 mg12155mol-innov2021
HPAI-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to human Plasminogen Activator Inhibitor (PAI-1) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of human PAI-1 antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
HPAITPAKT-COMTissue-type plasminogen activator (tPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. Plasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system and forms a 1:1 covalent complex with tPA and uPA. PAI-1 tPA complex increases during pregnancy, artherosclerosis, sepsis, and are associated with myocardial infarction reoccurrence. High levels of PAI-1 tPA complex in breast cancer cytosols are associated with poor survival. PAI-1 tPA complex levels may also be useful as a prognostic indicator for renal/bladder cancer, multiple organ failure, and stroke. The sensitive quantitative measurement of total human PAI-1 tPA complex antigen in plasma, serum, urine, cell culture media, or tissue extract samples is easily performed with this 96 well strip format ELISA kit. <b>Free tPA and PAI-1 will not be detected by this assay.</b> Concentration of PAI-1 tPA complex in normal human plasma was found to be 2.8 ng/ml. The assay measures PAI-1 tPA complex in the 0.5-200 ng/ml range. Samples with complex levels above 200 ng/ml should be diluted in plasma or similar fluid devoid of PAI-1 or tPA. Human PAI-1 in samples will bind to the monoclonal capture antibody coated on the microtiter plate. Free, latent, and complexed PAI-1 will react with the capture antibody. After appropriate washing steps, polyclonal anti-human tPA primary antibody binds to the captured PAI-1/tPA complex. Excess primary antibody is washed away and bound antibody is then reacted with peroxidase conjugated secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of PAI-1/tPA complex. Color development is proportional to the concentration of PAI-1/tPA complex in the samples. A standard calibration curve is prepared in PAI-1 depleted plasma using dilutions of purified PAI-1 tPA complex and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8075mol-innov2021
HPAIUPAKT-COMUrokinase plasminogen activator (uPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion/migration. Plasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system and forms a 1:1 covalent complex with tPA and uPA. The sensitive quantitative measurement of total human PAI-1 uPA complex antigen in plasma, serum, urine, cell culture media, or tissue extract samples is easily performed with this 96 well strip format ELISA kit. Concentrations of PAI-1 uPA complex in normal human plasma are low. The median concentration of complex in plasma samples from breast cancer patients was 0.068 ng/ml. Complex concentration in primary breast cancer tumor tissue extracts varied from 0.22-5.3 ng/mg total protein and were prognostic for decreased tumor size and grade and increased survival. Levels were associated with adverse grade and poor survival in a separate study. Values for lung cancer tumor tissue extracts were similar to breast cancer and varied from 0.11-5.74 ng/mg total protein. The assay measures PAI-1 uPA complex in the 0.1-100 ng/ml range. Samples with complex levels above 100 ng/ml should be  diluted in plasma or similar fluid devoid of PAI-1 or uPA. Human uPA will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human PAI-1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 uPA complex in the samples. A standard calibration curve is prepared in PAI-1 depleted plasma using dilutions of purified PAI-1 uPA complex and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8075mol-innov2021
HPAI-YSYA triple mutation on the wild-type background makes this Human PAI-1 selectively inhibit tPA. Urokinase inhibition is limited to 1/25,000 of tPA inhibition by the P3Tyr-P2Ser-P1Tyr mutation.<br><br> 
<b>References</b>:<br> Sherman PM. et al. (1995) J Biol Chem 270:9301-9306.
0.5 mg12155mol-innov2021
HPCHuman protein C is prepared from fresh frozen human plasma using a combination of salt precipitations and column chromatography. The protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated to the serine protease Activated Protein C (APC) by alpha-thrombin or the complex of alpha-thrombin/thrombomodulin. APC is a potent anticoagulant through the selective inactivation of Factors Va and VIIIa.0.1 mg4675mol-innov2021
HPCR-HISEndothelial Protein C Receptor (EPCR) is a type I transmembrane glycoprotein in the CD1/MHC family expressed in endothelial cells. Binding of Protein C to EPCR enhances activation by the thrombin-thrombomodulin complex. Bound APC cleaves Protease-Activated Receptor 1 (PAR1) leading to up-regulation of Protein C-induced genes. The glycosylated extracellular domain (Ser18-Ser210) is recombinantly produced in mammalian cell culture and purified then sterile filtered and lyophilized. Contains a 6X-Histidine tag at C terminus for purification. The protein purity is determined by SDS-PAGE. Add PBS to greater than 0.1 mg/ml, aliquot and freeze unused portion.0.05 mg7990mol-innov2021
HPF4Human PF-4 is prepared from the supernatant of thrombin-activated platelets by heparin-agarose affinity chromatography. Purity is assessed by SDS-PAGE analysis and heparin-neutralizing activity is verified by clotting assay.0.1 mg4335mol-innov2021
HPF4-RHuman PF-4 is expressed recombinantly and purified by chromatography. The purified protein in PBS is sterile filtered and lyophilized. Protein identity is confirmed by mass spectrometry (7.8 kDa monomer) and N-terminal sequencing (M-E-A-E-E). Purity is >95 percent by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.2 mg17680mol-innov2021
HPKZymogen precursor of the plasma serine protease kallikrein. Human Prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contact activation, kinin formation and fibrinolysis. Prekallikrein purity is  >95percent by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).1.0 mg7480mol-innov2021
HPKAActivation of Prekallikrein with Factor alpha-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is >95percent by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).1.0 mg8670mol-innov2021
HPKA-BIOActive Human Kallikrein is biotinylated on lysine residues. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).0.1 mg6885mol-innov2021
HPKA-BIO-LActive Human Kallikrein is biotinylated on lysine residues then lyophilized. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease). Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg6885mol-innov2021
HPKKT-TOTPrekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma prekallikrein is associated with diabetes and cardiovascular disease.  The sensitive quantitative measurement of total human prekallikrein antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Kallikrein will be detected by the assay.</b> The concentration of prekallirein in normal human plasma is 15-55 ug/ml. The assay measures human prekallikrein in the 0.02-10 ug/ml range. Samples giving human prekallikrein levels above 10 ug/ml should be diluted in blocking buffer before use. Normal human plasma should be applied directly to the plate or at a 1:5 dilution for best results. Human prekallikrein will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human prekallikrein primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prekallikrein in the samples. A standard calibration curve is prepared using dilutions of purified prekallikrein and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>1 kit8415mol-innov2021
HPLA-SCFreshly collected and frozen normal human plasma in sodium citrate. Useful as a control for depleted plasma.10 ml510mol-innov2021
HPLA-SC-C1INHHuman C1 Inhibitor (also known as plasma protease C1 inhibitor, C1 esterase inhibitor, C1-inhibiting factor, C1-INH, and C1INA) is a single chain glycoprotein which inhibits C1, C1r, C1s, plasma kallikrein, plasmin, Factors XIa and XIIa. Prepared by immunodepletion from plasma found negative by FDA accepted methods for Anti-HIV, Anti-HCV, Syphilis, HBsAg, HIV-1 RNA and HCV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).5.0 ml22270mol-innov2021
HPLA-SC-FBNPrepared from frozen human plasma by affinity chromatography.10 ml3400mol-innov2021
HPLA-SC-PAIPrepared from frozen human plasma using immobilized anti-human PAI-1 IgG.10 ml5015mol-innov2021
HPLA-SC-PAI-tPAPrepared from frozen human plasma using immobilized antibodies to human PAI-1 and human tPA.10 ml10370mol-innov2021
HPLA-SC-PGPrepared from frozen human plasma by immobilized lysine affinity chromatography.25 ml7905mol-innov2021
HPLA-SC-PRENPrepared from frozen human plasma using immobilized anti-human Renin IgG.10 ml5185mol-innov2021
HPLA-SC-tPAPrepared from frozen human plasma using immobilized anti-human tPA IgG.10 ml5015mol-innov2021
HPLA-SER-GFPrepared from frozen human serum using immobilized Protein A.100 ml5185mol-innov2021
HPLA-SER-GFAPrepared from frozen human serum using immobilized Peptide M.5 ml5185mol-innov2021
HPLGKT-TOTPlasminogen is a single chain glycoprotein zymogen and is the precursor of the fibrinolytic enzyme plasmin. Plasminogen deficiencies are classified as hypoplasminogenemia (Type I) or dysplasminogenemia (Type 2) and are associated with decreased extracellular fibrin clearance leading to mucous membrane lesions and ligneous conjunctivitis. The sensitive quantitative measurement of total human plasminogen antigen in plasma, serum, or cell culture media  samples is easily performed with this 96 well strip format ELISA kit. <b>Plasminogen, plasmin and plasmin antiplasmin complex will be detected by the assay.</b> The concentration of plasminogen in normal human plasma is 195 ug/ml. The assay measures total human plasminogen in the 0.5-500 ng/ml range. Samples giving human plasminogen levels above 100 ng/ml should be diluted in a similar fluid depleted of plasminogen or blocking buffer before use. A 1:10,000 dilution for plasma is suggested for best results. Human plasminogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human plasminogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of plasminogen in the samples. A standard calibration curve is prepared using dilutions of purified plasminogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>1 kit4420mol-innov2021
HPL-IWe have immobilized human Lys plasmin on agarose resin by coupling of primary amines. Plasmin retains catalytic activity when coupled and may be used to efficiently activate single-chain tPA and uPA to the two-chain form (1). It may also be used to convert plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids. References: 1. Wallen, P. et al. (1982) Biochim. Biophys. Acta 719:318-328.1.0 ml5950mol-innov2021
HPLMPrepared from Glu plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg4080mol-innov2021
HPLM-INPrepared from Lys plasmin by active site-specific inactivation with Phe-Pro-Arg chloromethyl ketone.1.0 mg7990mol-innov2021
HPREN<p> 
Recombinantly produced in HEK cell culture as untagged native form prorenin and purified by affinity chromatography. Fully activatable to renin by catalytic amounts of trypsin. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits a low level of enzymatic activity relative to renin which is generated from prorenin by proteolytic cleavage of the first ~43 amino acids at the N-terminus. This so called prosegment appears to block the full enzymatic potential of the active site (1). Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects(2).<br><br> 
 
1) A.H. Jan Danser; Jaap Deinum ; Renin, Prorenin and the Putative (Pro)renin Receptor). Hypertension. 2005;46:1069. 
<br><br> 
 
2) Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. 
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular 
complications. N Engl J Med. 1985;312:1412-1417. 
<br><br><br><br><blink> 
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0.1 mg3995mol-innov2021
HPREN-HISRecombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification. Fully activatable to renin by catalytic amounts of trypsin. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits a low level of enzymatic activity relative to renin which is generated from prorenin by proteolytic cleavage of the first ~43 amino acids at the N-terminus. This so called prosegment appears to block the full enzymatic potential of the active site (1). Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects(2).<br><br>

1) A.H. Jan Danser; Jaap Deinum ; Renin, Prorenin and the Putative (Pro)renin Receptor). Hypertension. 2005;46:1069.
<br><br>

2) Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M.
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular
complications. N Engl J Med. 1985;312:1412-1417.
0.1 mg3995mol-innov2021
HPRENKTThe <b>first</b> and <b>only</b> commercial assay that <i>directly</i> measures human prorenin (U.S. Patent No. 9,085,795). Prorenin is measured directly by ELISA without pretreatment of samples or conversion to renin.<br><br> 
Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects. Plasma and serum concentrations increase in several conditions such as pregnancy, progressive diabetes mellitus, diabetes mellitus with microvascular disease, and diabetic retinopathy. The sensitive quantitative measurement of human prorenin in plasma or serum samples is easily performed with this 96 well strip format ELISA kit. <b>Active renin will not be detected by the assay. This kit does not cross react with mouse or rat prorenin.</b> The concentration of prorenin is 173 pg/ml in normal human plasma and 109 pg/ml in normal human serum as determined by indirect methods. The assay measures human prorenin in the 0.02-10 ng/ml range. Samples giving human prorenin levels above 10 ng/ml should be diluted in <a href=http://www.mol-innov。。com/item/Human-Renin-Prorenin-double-Depleted-Plasma>prorenin depleted plasma</a> or blocking buffer before use. Samples of human plasma and serum may be applied directly to the plate. Human prorenin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human prorenin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prorenin in the samples. A standard calibration curve is prepared using dilutions of purified prorenin in depleted plasma and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
The standard curve for this kit is generated using included prorenin depleted human plasma and is best suited for measurement of prorenin in plasma or serum. This kit is also available with a standard curve in BSA/TBS for researchers measuring prorenin in culture media under <a href=http://www.mol-innov。。com/products/human-prorenin-elisa-kit-for-non-plasma-samples/><font color=blue>catalog number HPRENKT-NP</font></a>.
1 kit8075mol-innov2021
HPRENKT-NPThe <b>first</b> and <b>only</b> commercial assay that <i>directly</i> measures human prorenin (U.S. Patent No. 9,085,795). Prorenin is measured directly by ELISA without pretreatment of samples or conversion to renin.<br><br> 
Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects. Plasma and serum concentrations increase in several conditions such as pregnancy, progressive diabetes mellitus, diabetes mellitus with microvascular disease, and diabetic retinopathy. The sensitive quantitative measurement of human prorenin in cell culture media or urine samples is easily performed with this 96 well strip format ELISA kit. <b>Active renin will not be detected by the assay. This kit does not cross react with mouse or rat prorenin.</b> The assay measures human prorenin in the 0.01-10 ng/ml range. Samples giving human prorenin levels above 10 ng/ml should be diluted in blocking buffer before use. Human prorenin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human prorenin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prorenin in the samples. A standard calibration curve is prepared using dilutions of purified prorenin in blocking buffer and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
The standard curve for this kit is generated using TBS/BSA and is best suited for measurement of prorenin in cell culture media or urine. This kit is also available with a standard curve in prorenin depleted human plasma for researchers measuring prorenin in plasma or serum under <a href=http://www.mol-innov。。com/products/human-prorenin-elisa-kit><font color=blue>catalog number HPRENKT</font></a>. 
 <br><br><font color=red>This assay uses a unique antibody to only detect prorenin.<br><br>
1 kit8075mol-innov2021
HPRLProlactin (PRL, Mammotropin, Luterotropic hormone, Lutetropin) is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Expressed recombinantly and purified by chromatography. >95percent pure by SDS-PAGE and biologically active. Add deionized water to original volume, aliquot and freeze unused portion.0.05 mg4845mol-innov2021
HPRLKTProlactin (PRL) is a 199 aa, 23kD peptide hormone that is secreted primarily by the pituitary gland in both males and females, though its major roles are in pregnancy and lactation. Prolactin may have a role in breast cancer development, with higher prolactin levels correlating with postmenopausal breast cancer risk.
 The sensitive quantitative measurement of total human prolactin antigen in plasma, serum, or breast milk samples is easily performed with this 96 well strip format ELISA kit. The concentration of prolactin in normal human plasma ranges from 2-18 ng/ml in males, 2-29 ng/ml in nonpregnant females, and 10-209 ng/ml in pregnant females. The assay measures total human prolactin in the 0.1-100 ng/ml range. Samples with human prolactin levels above 100ng/ml should be diluted in blocking buffer before use. Normal plasma should not require dilution before use in this assay. A 1:2 to 1:4 dilution for breast milk is suggested for best results. Human prolactin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human prolactin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prolactin in the samples. A standard calibration curve is prepared using dilutions of purified prolactin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.
1 kit5185mol-innov2021
HPRLRProlactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain is expressed recombinantly and purified by chromatography. >95percent pure by SDS-PAGE and biologically active. Add deionized water to original volume, aliquot and freeze unused portion.0.02 mg4845mol-innov2021
HPRLR-FCProlactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain (Gln25-Asp234) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured by inhibitory activity toward prolactin-induced proliferation of Nb2-11 rat lymphoma cells (Gout et al. (1980) Cancer Res. 40:2433). ED50 for this effect is typically < 1.0 ug/ml in the presence of 0.5 ng/ml of recombinant human Prolactin. Add deionized water to original volume, aliquot and freeze unused portion.<br>
<img src=/img/prolactin-receptor.jpg><br>
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
0.1 mg5185mol-innov2021
HPSHuman protein S is isolated from fresh frozen plasma by a combination of conventional methods and immunoaffinity chromatography. Protein S exists in two forms in human plasma, as the free protein and in complex with C4b-binding protein. This is the free protein from plasma which serves as a cofactor for the anticoagulant activity of activated protein C. Human protein S is a single-chain glycoprotein with >95percent purity as determined by SDS-PAGE.1.0 mg11220mol-innov2021
HPTKT-TOTProthrombin is a single-chain vitamin K dependent 579 amino acid glycoprotein zymogen. Prothrombin levels are decreased by anticoagulant therapy, vitamin K deficiency and severe liver disease. Elevated plasma prothrombin is associated with a single nucleotide change at position 20210. The sensitive quantitative measurement of total human prothrombin antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Thrombin and thrombin-antithrombin complex will be detected by the assay.</b> Prothrombin in normal human plasma ranges from 110-212 ug/ml with an average concentration of 150 ug/ml. The assay measures total human prothrombin in the 0.25-100 ng/ml range. Samples giving human prothrombin levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:5,000 to 1:40,000 dilution for plasma is suggested for best results. Human prothrombin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human prothrombin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prothrombin in the samples. A standard calibration curve is prepared using dilutions of purified prothrombin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The human prothrombin standard provided is calibrated against a reference plasma standardized to the SSC/ISTH Secondary Coagulation Standard distributed by NIBSC, South Mimms, Potters Bar, Hertfordshire, UK.</strong>1 kit5185mol-innov2021
HPZHuman protein Z is isolated from fresh frozen plasma by a combination of precipitations and column chromatography. HPZ purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.0.5 mg13005mol-innov2021
HREN-HISRecombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification. Molecular Innovations human renin is produced from the proenzyme prorenin by proteolytic cleavage of a 43 amino acid N-terminal prosegment using limited enzymatic digestion by immobilized trypsin. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits a low level of enzymatic activity relative to renin which is generated from prorenin by proteolytic cleavage of the first ~43 amino acids at the N-terminus. This so called prosegment appears to block the full enzymatic potential of the active site (1). Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects(2).<br><br> 
 
1) A.H. Jan Danser; Jaap Deinum ; Renin, Prorenin and the Putative (Pro)renin Receptor). Hypertension. 2005;46:1069. 
<br><br> 
 
2) Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. 
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular 
complications. N Engl J Med. 1985;312:1412-1417.
0.1 mg3995mol-innov2021
HSAMolecular Innovations albumin is purified by proprietary chromatographic and cold ethanol fractionation methods. Heat shock albumin sold by our competitors is less pure and may contain denatured albumin.<br><br> 
Albumin is a water-soluble protein with considerable structural stability. It is the most abundant of the human proteins, making up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. For over fifty years, it has been used as a therapeutic agent for the restoration and maintenance of circulating blood volume for trauma, surgery and burn patients. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.  Add deionized water or buffer to desired volume, aliquot and freeze unused portion.<br><br> 
<font color=#CC0000>Temporary price break:<br> 
100 mg for <strike>$220</strike> now on sale for $95!<br> 
200 mg for <strike>$330</strike> now on sale for $175!</font>
100 mg1700mol-innov2021
HSAKTAlbumin is a water-soluble protein with considerable structural stability which makes up 60 percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. The sensitive quantitative measurement of total human albumin (human serum albumin, HSA) in plasma, serum, urine or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. Albumin is present in normal human plasma at a concentration of 35-50 mg/ml.  The assay measures human albumin in the 1-500 ng/ml range. Samples giving human albumin levels above 500ng/ml should be diluted in 1X diluent before use. A 1:1,000,000 to 1:2,000,000 dilution for normal plasma or a 1:500 to 1:1,000 dilution for urine is suggested for best results. Human albumin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human albumin primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of human albumin in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human albumin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Also available: High quality <a href=http://www.mol-innov。。com/item/Albumin-Human-Plasma>human albumin</a> and <a href=http://www.mol-innov。。com/item/Prealbumin-Human-Plasma>human prealbumin</a>.
1 kit6120mol-innov2021
HS-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free.50 mg1445mol-innov2021
HSIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total horse IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react with human, mouse, rat, dog, sheep, pig, rabbit or monkey at the recommended dilution.</b> The concentration of IgG in normal adult horse serum is 19.13 mg/ml. The assay measures horse IgG in the 0.2-200 ng/ml range. Samples giving horse IgG levels above 200 ng/ml should be diluted in blocking buffer before use. A 1:2,000,000 to 1:16,000,000 dilution for serum is suggested for best results. Horse IgG will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-horse IgG primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of horse IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified horse IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
HSPATransthyretin (TTR), also known as prealbumin (PALB), is found in plasma at 30 mg per 100 ml. Transthyretin  functions in the transport of thyroxine, vitamin A, and retinol-binding protein. Clinically, prealbumin is a sensitive indicator of impaired liver function; low levels are found in viral hepatitis, cirrhosis, malnutrition, inflammation, and surgical trauma. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.1.0 mg3995mol-innov2021
HTAFIKTThrombin Activatable Fibrinolysis Inhibitor (TAFI), also known as carboxypeptidase B2 (PCB2), plasma carboxypeptidase-B (pCB), and carboxypeptidase-U (CPU), is a 401 amino acid 58 kDa plasma glycoprotein that is activated by thrombin. Activated TAFI (TAFIa) cleaves fibrin carboxy-terminal lysines reducing plasminogen and tPA binding sites resulting in downregulation of fibrinolysis. Although mice made genetically deficient for TAFI do not show a marked phenotype, change in human plasma TAFI level has been associated with many cardiovascular disorders. The sensitive quantitative measurement of total human TAFI antigen in plasma and serum is easily performed with this 96 well strip format ELISA kit. <b>TAFI and TAFIa will be detected by the assay.</b> The average concentration of TAFI in normal human plasma is 4.2 µg/ml. The assay measures total human TAFI in the 2-500 ng/ml range. Samples giving human TAFI levels above 500 ng/ml should be diluted in diluent before use. A 1:100 to 1:1,000 dilution for normal human plasma or serum is suggested for best results. 
 
Human TAFI will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human TAFI primary antibody binds to the captured protein. Excess primary antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human TAFI. Color development is proportional to the concentration of total TAFI antigen in the samples. All reagents and standards are provided in these ELISA kits.
1 kit6715mol-innov2021
HTAQTaqTivate Hot Start Taq DNA Polymerase is a chemically modified hot-start DNA polymerase designed for reducing non-specific DNA amplification due to primer-dimer formation. TaqTivate requires a 95C activation time of only two minutes for faster cycling reactions. Chemical modification keeps TaqTivate free of contaminating DNA from biological modifying agents such as antibodies. This highly robust enzyme will create products with dA overhangs at 3’ ends. Suitable for Standard Endpoint PCR, Colony PCR, Genotyping, TA Cloning, and qPCR of DNA templates up to 5kb. TaqTivate offers higher yields than some leading competitors with excellent lot-to-lot reproducibility. TaqTivate undergoes extensive quality control and is free of contaminating endonucleases. Available with your choice of complimentary MgCl2 or MgCl2 free 10X reaction buffer.500 units3230mol-innov2021
HTAQGREENTaqTivate Hot Start Taq MantisGreen Master Mix is an optimized, ready-to-use mix that contains dNTPs, MgCl2, optimized buffers, MantisGreen loading dyes and our TaqTivate recombinant hot start Taq DNA polymerase. Reactions can go directly from PCR tube to gel. The mix is a 2X formulation that requires only the addition of primers, template and water. MantisGreen dual-color loading dyes do not inhibit PCR and make monitoring progress easy during electrophoresis. The dyes run outside the range of typical PCR products and therefore do not obscure visualization. The blue dye runs at 4kb and the yellow dye runs under 25bp. TaqTivate requires a 95C activation time of only two minutes for faster cycling reactions. Chemical modification keeps TaqTivate free of contaminating DNA from biological modifying agents such as antibodies. TaqTivate 2X Master Mix provides robust amplification of templates up to 5kb and reduces non-specific DNA amplification due to primer-dimer formation. Suitable for direct-to-gel Standard Endpoint PCR, Colony PCR, Low Copy PCR, Genotyping, and TA Cloning. Also available without loading dyes.<br><br><b>Reaction setup:</b> The following setup is recommended for a 50&micro;l reaction but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Component</th><th>Volume</th><th>Final Concentration</th></tr> <tr><td>Master Mix</td><td>25&micro;l</td><td>1X</td></tr> <tr><td>5' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td></tr> <tr><td>3' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td> <tr><td>DNA Template</td><td>0.1-5&micro;l</td><td>&gt;1ng</td></tr> <tr><td>Nuclease Free Water</td><td colspan=2>QS to 50&micro;l</td></tr></table> <br><br><b>Thermal cycling conditions:</b> The following general cycling conditions are recommended but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Cycling Step</th><th>Temperature</th><th>Holding Time</th><th>Cycles</th></tr> <tr><td>Initial Denaturation<br>and Hot Start Activation</td><td>94&deg;C</td><td>30sec-2min</td><td>1</td></tr> <tr><td>Denaturation</td><td>94-96&deg;C</td><td>15-30sec</td><td rowspan=3>20-30</td></tr> <tr><td>Annealing*</td><td>55-65&deg;C</td><td>15-60sec</td></tr> <tr><td>Extension</td><td>70-72&deg;C</td><td>1min per kb</td></tr> <tr><td>Final Extension</td><td>70-72&deg;C</td><td>0-10min</td><td>1</td></tr> </table> *Annealing temperature will depend on primer length and composition. Generally, begin 5&deg;C below primer Tm.</td>100 rxn2040mol-innov2021
HTAQMIXTaqTivate Hot Start Taq Master Mix is an optimized, ready-to-use mix that contains dNTPs, MgCl2, optimized buffers and our TaqTivate recombinant hot start Taq DNA polymerase. It is supplied in a 2X formulation that requires only the addition of primers, template and water. TaqTivate requires a 95C activation time of only two minutes for faster cycling reactions. Chemical modification keeps TaqTivate free of contaminating DNA from biological modifying agents such as antibodies. TaqTivate 2X Master Mix provides robust amplification of templates up to 5kb and reduces non-specific DNA amplification due to primer-dimer formation. Suitable for Standard Endpoint PCR, Colony PCR, Low Copy PCR, Genotyping, and TA Cloning. Also available containing MantisGreen dual-color loading dyes.<br><br><b>Reaction setup:</b> The following setup is recommended for a 50&micro;l reaction but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Component</th><th>Volume</th><th>Final Concentration</th></tr> <tr><td>Master Mix</td><td>25&micro;l</td><td>1X</td></tr> <tr><td>5' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td></tr> <tr><td>3' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td> <tr><td>DNA Template</td><td>0.1-5&micro;l</td><td>&gt;1ng</td></tr> <tr><td>Nuclease Free Water</td><td colspan=2>QS to 50&micro;l</td></tr></table> <br><br><b>Thermal cycling conditions:</b> The following general cycling conditions are recommended but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Cycling Step</th><th>Temperature</th><th>Holding Time</th><th>Cycles</th></tr> <tr><td>Initial Denaturation<br>and Hot Start Activation</td><td>94&deg;C</td><td>30sec-2min</td><td>1</td></tr> <tr><td>Denaturation</td><td>94-96&deg;C</td><td>15-30sec</td><td rowspan=3>20-30</td></tr> <tr><td>Annealing*</td><td>55-65&deg;C</td><td>15-60sec</td></tr> <tr><td>Extension</td><td>70-72&deg;C</td><td>1min per kb</td></tr> <tr><td>Final Extension</td><td>70-72&deg;C</td><td>0-10min</td><td>1</td></tr> </table> *Annealing temperature will depend on primer length and composition. Generally, begin 5&deg;C below primer Tm.</td>100 rxn2040mol-innov2021
HTATKT-COMAntithrombin III is a glycosylated plasma serine protease inhibitor that forms a stoichiometric complex with coagulation cascade enzymes. Thrombin is a two-chain vitamin K-dependent glycosylated serine protease that is activated from prothrombin in the coagulation cascade. Antithrombin III inhibits thrombin with heparin enhanced kinetics and forms a 1:1 covalent complex. The sensitive quantitative measurement of total human Thrombin Antithrombin (TAT) Complex antigen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. <b>Free thrombin, prothrombin and antithrombin III will not be detected by this assay.</b> In-house testing determined human TAT complex concentrations of 10 ng/ml in plasma and 52 ug/ml in serum. The assay measures total human TAT complex in the 1-1,000 ng/ml range. Samples giving human TAT complex levels above 1,000 ng/ml should be diluted in blocking buffer before use. Normal human plasma samples should be applied directly to the plate without dilution. A 1:500 to 1:1,000 dilution for normal human serum is suggested for best results. Human TAT complex in samples will bind to the anti-human thrombin capture antibody coated on the microtiter plate. After appropriate washing steps, monoclonal anti-human antithrombin primary antibody binds to TAT complex captured on the plate. Excess antibody is washed away and bound monoclonal antibody is then reacted with the secondary antibody conjugated to horseradish peroxidase. TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of TAT complex. Color development is proportional to the concentration of TAT complex in the samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
HTFTransferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100 ml. The Holo form of transferrin is iron saturated and also called Siderophilin. The specific iron-binding protein in plasma, it has a role in the transportation and distribution of iron among the body organs, in iron metabolism and prevention of iron loss via the kidneys. Stored in bone marrow as Tf-bound iron, it also possesses bacteriostatic and fungistatic activity. Clinically, decreases in transferrin are observed in congenital disorders, newborns, inflammatory diseases, hypoproteinemias and nephrotic syndrome; increases are found in pregnancy, iron-deficiency anemias, and inoculation hepatitis. Transferrin is required by all types of cells in cultures for maximal growth. It is, therefore, an important transport factor used in defined culture media.   Each human transferrin molecule has the ability to carry two iron ions in the ferric form (Fe3+). Dissolves in water at 10 mg per ml. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Total protein determination by the Lowry method. >95percent pure and shows only one major band corresponding to the molecular weight of Transferrin by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.100 mg4165mol-innov2021
HT-GFPurified from normal serum by immobilized Protein G. >95 percent pure by SDS-PAGE and preservative free.10 mg1105mol-innov2021
HTHROM-AHuman alpha-thrombin is prepared from purified prothrombin by activation with coastal taipan venom followed by affinity chromatography. Purity is verified by SDS-PAGE analysis and specific activity in NIH thrombin units is determined by chromogenic substrate.1.0 mg4250mol-innov2021
HTHROM-BIOBiotinylated thrombin is useful for cleavage of proteins and peptides at the enzyme recognition sequence Leu-Val-Pro-Arg-||-Gly-Ser. Biotinylated thrombin is then easily removed from the reaction with immobilized avidin agarose resin. This preparation is &gt;95% pure on SDS-PAGE and is tested for activity using thrombin chromogenic substrate and cleavage control protein.<br><br> 
Biotinylated Thrombin Cleavage Protocol</u><br> 
1. Make a 10X cleavage buffer consisting of 0.2M Tris-HCl, 1.5M NaCl, 0.025M CaCl2, pH 8.4.<br> 
2. Combine 500ul of 10X cleavage buffer, 1mg of target protein, and 1U of biotinylated thrombin in a total of 5ml.<br> 
3. Incubate overnight at room temperature.<br> 
4. Remove biotinylated thrombin with immobilized avidin or streptavidin agarose resin according to the manufacturer's recommended directions. This resin cannot be reused.<br> 
5. Residual uncleaved fusion tagged protein along with cleaved purification tag in the reaction can usually be removed by reapplying to the original purification resin after reequilibration in binding buffer.<br><br> 
<u>Notes</u>: Optimization of biotinylated thrombin protocol is required for specific applications. Recommended reaction conditions are pH 7.0 to 9.0 at 20C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature. For example, addition of 2U of biotinylated thrombin and incubation at 37C will result in accelerated thrombin digestion (30-60 minutes).<br> 
Cleavage at sites similar to the enzyme recognition sequence can be limited by decreasing enzyme to protein substrate ratio and incubation temperature. A pilot scale digestion is recommended for optimization of the reaction by removing samples at 2, 4, 8, and 16 hours and analyzing by SDS-PAGE.
0.01 mg1700mol-innov2021
HTPAHuman tissue-type plasminogen activator (tPA) is a 527 amino acid glycoprotein.  Synthesized from cDNA from a human melanoma cell line.  It is recombinantly produced in Chinese Hamster Ovary (CHO) cells.  Fully active, >85percent single chain.0.1 mg3825mol-innov2021
HTPA2A153Produces excellent western blots with free and complexed forms of tPA. Epitope localized to the heavy chain of human tPA. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg7565mol-innov2021
HTPA-ALAThis human tPA has an active site serine to alanine mutation which renders it catalytically inactive. The mutation site is S478A on the mature protein and S513A on the complete mRNA sequence (UniProtKB: locus TPA_HUMAN, accession P00750). It is >90percent single chain and retains exosite binding as well as other properties of wild type tPA.  Recombinantly produced in insect cells.
<br><Br>
Reference:<br>
Identification of a conformationally distinct form of plasminogen
activator inhibitor-1, acting as a noninhibitory substrate for tissue-
type plasminogen activator<br>
PJ Declerck, M De Mol, DE Vaughan, and D Collen<br>
J. Biol. Chem., Jun 1992; 267: 11693 - 11696.
0.1 mg5695mol-innov2021
HTPA-ALANCHuman tPA with a double mutation that is permanently single chain and lacks catalytic activity. The non-catalytic mutation site is S478A on the mature protein and S513A on the complete mRNA sequence (UniProtKB: locus TPA_HUMAN, accession P00750). The non-cleavable mutation site is R275E on the mature protein and R310E on the complete mRNA sequence (UniProtKB: locus TPA_HUMAN, accession P00750). Recombinantly produced in insect cells.0.1 mg5695mol-innov2021
HTPA-FITCFluorescein labeled tPA, >85percent single chain. 100percent complex formation with PAI-1.0.1 mg7650mol-innov2021
HTPA-IMay be used to immunopurify monoclonal and polyclonal antibodies directed against human tPA. May be used repeatedly.1.0 ml9860mol-innov2021
HTPAKTTissue plasminogen activator (tPA) is a serine protease that catalyzes the activation of plasminogen to plasmin. Clinical studies have indicated that high tPA levels may increase the risk for thrombosis, whereas decreased levels may cause neuronal plasticity and degeneration. The sensitive quantitative measurement of functionally active human tPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The basal level of tPA in healthy humans was found to be between 0.2-2 IU/ml. The assay measures active tPA in the 0.01-1 IU/ml range. Samples giving human tPA levels above 1 IU/ml should be diluted in blocking buffer before use. Samples of human plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation as platelets can release PAI-1, which in turn could potentially form a complex with active tPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the diluent provided in the kit. Serum and cell culture media at neutral pH may also be used. Functionally active tPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Complexed tPA will not bind to the PAI-1 and will not be detected by the assay. This kit cross reacts with rat, pig, and dog tPA and does not cross react with mouse tPA.</b> After appropriate washing steps, polyclonal anti-human tPA primary antibody binds to the captured enzyme. Excess antibody is washed away and bound antibody is reacted with peroxidase conjugated secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active tPA in the samples. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><strong>The Human tPA standard provided in this kit is calibrated against the WHO International Standard for Human tPA (NIBSC Code 98/714).</strong><br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a></font><br>
1 kit8075mol-innov2021
HTPAKT-TOTTissue plasminogen activator (tPA) is a serine protease that catalyzes the activation of plasminogen to plasmin. Clinical studies have indicated that high tPA levels may increase the risk for thrombosis, whereas decreased levels may cause neuronal plasticity and degeneration. The sensitive quantitative measurement of total human tPA antigen in plasma, serum, urine, cell culture media, or tissue extract samples is easily performed with this 96 well strip format ELISA kit. The basal level of tPA in healthy males and females, age 25-34 years, were found to be 5.5 ng/ml and 4.0 ng/ml respectively. The assay measures human tPA in the 0.02-10 ng/ml range. Samples giving human tPA levels above 10 ng/ml should be diluted in blocking buffer before use. Human tPA will bind to the affinity purified capture antibody coated on the microtiter plate. <b>Free and complexed tPA will be detected by the assay. This kit cross reacts with mouse, rat, and pig tPA and does not cross react with rabbit, cyno monkey, rhesus monkey, guinea pig, dog, and sheep tPA.</b> After appropriate washing steps, monoclonal anti-human tPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated secondary antibody. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of human tPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Human-tPA-Antigen-Capture-Plate>tPA Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8075mol-innov2021
HTPA-NCThe addition of an arginine to glutamic acid mutation generates human tPA that is 100percent single chain and resistant to cleavage by plasmin. The mutation site is R275E on the mature protein and R310E on the complete mRNA sequence (UniProtKB: locus TPA_HUMAN, accession P00750). Recombinantly produced in insect cells.
<br>
References:<br>
1. Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis.<br>
KM Tate, DL Higgins, WE Holmes, ME Winkler, HL Heyneker, and GA Vehar<br>
Biochemistry, January 27, 1987; 26(2): 338-43.
<br>
2. Plasmin-Mediated Fibrinolysis by Variant Recombinant Tissue Plasminogen Activators<br>
Shoko Urano, Alan R. Metzger, and Francis J. Castellino<br>
PNAS, Apr 1989; 86: 2568 - 2571.
<br>
3. Plasminogen activation with single-chain urokinase-type plasminogen
activator (scu-PA). Studies with active site mutagenized plasminogen
(Ser740Ala) and plasmin-resistant scu-PA (Lys158Glu) <br>
HR Lijnen, B Van Hoef, L Nelles, and D Collen<br>
J. Biol. Chem., Mar 1990; 265: 5232 - 5236.
0.1 mg5695mol-innov2021
HTPA-TCActivated from single-chain form with immobilized plasmin.  100percent complex formation with human PAI-1.0.1 mg5695mol-innov2021
HTPA-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to human Tissue-type Plasminogen Activator (tPA) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of human tPA antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
HTPA-TRTexas red labeled tPA, >85percent single chain. 100percent complex formation with PAI-1.0.1 mg6885mol-innov2021
HTRYPHydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in patients with cystic fibrosis. Trypsinogen has three isoforms: cationic (trypsinogen 1), anionic (trypsinogen 2, MW 22,500), and mesotrypsinogen (trypsinogen 3, MW, 25,000). This trypsin is the cationic form. Activity: 2.5 units per mg protein. One unit is defined as the amount of enzyme that hydrolyzes one umole of N-benzoyl-DL-arginine-pNA per minute at 25oC in 200 mM Tris-HCl, pH 7.8, with 20 mM CaCl2. Prepared from tissue shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg5440mol-innov2021
HTSPA cellular adhesion protein. Thrombospondin is a component of the coagulation mechanism and is believed to have potential as a marker for platelet activation and renal failure. Aliquoted in siliconized tubes. Prepared from platelets shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.025 mg4250mol-innov2021
HU-FABIsolated fab fragments can be used to bind antigen to antibody in solution or on the cell surface without causing the undesired complications of cross-linking and precipitation, or patching and capping, respectively. No reaction by IEP to antisera to human IgG-fc. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg5100mol-innov2021
HU-FCThe IgG fc fragment does not bind antigen; however, it does contain the classic antigenic determinants and biological activity with respect to cytotrophic reactions, binding of complement and catabolic rate control. No reaction by IEP to antisera to human IgG-fab. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg5100mol-innov2021
HU-GFPurified from normal serum by immobilized Protein A. IgG is the most abundant immunoglobulin in plasma, found at a concentration of 8 to 18 mg/ml. This immunoglobulin plays a very important role in the defense against infection for newborns because of its transfer through the placenta during pregnancy. It readily diffuses into the extravascular body spaces where it plays a major role in neutralizing bacterial toxins and in enhancing the phagocytosis of microorganisms. IgG binds to bacteria and these complexes adhere to phagocytic cells which have surface receptors specific for IgG. Prepared from serum shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.50 mg1870mol-innov2021
HU-GF-EDPurified from normal serum by immobilized Protein A using low endotoxin methodology. The purified protein is sterile filtered and lyophilized from azide free PBS. >95 percent pure by SDS-PAGE and <1 EU/mg.50 mg6885mol-innov2021
HU-IGAIgA is the most abundant immunoglobulin in body fluids and the second most abundant immunoglobulin in plasma, found at a concentration of 0.4 to 2.2 mg/ml. It plays a very important role in the first specific defense against natural infection. Secretory IgA differs from serum IgA in that it contains two additional peptides: the secretory component and the J chain. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg2380mol-innov2021
HU-IGA1MIn normal adult serum, the approximate percentage composition of IgA with respect to is subclasses is IgA1:90percent and IgA2:10percent. In secretory IgA, the subclass proportions may approach 50:50. The clinical significance of the subclasses has yet to be determined. No reaction by IEP to IgA2 antiserum. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg4930mol-innov2021
HU-IGA2MIn normal adult serum, the approximate percentage composition of IgA with respect to is subclasses is IgA1:90percent and IgA2:10percent. In secretory IgA, the subclass proportions may approach 50:50. The clinical significance of the subclasses has yet to be determined. Single arc by IEP against antisera to whole human serum, human IgA2, and human kappa. Not immunoreactive to antisera against human IgA1, IgG, IgD, IgE, IgM, and lambda by IEP. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg5950mol-innov2021
HUIGAKTHuman Immunoglobulin A (IgA) is the most abundant immunoglobulin in body fluids and the second most abundant immunoglobulin in plasma. IgA in serum is a primarily monomeric 160kDa glycoprotein that initiates defenses against natural infection through interaction with specific receptors and immune mediators. Each monomer consists of two heavy chains and two kappa or lambda light chains. A majority of serum IgA molecules are subclass IgA1 which have longer hinge regions than subclass IgA2. The sensitive quantitative measurement of total human IgA antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgA subclasses. The concentration of IgA in normal human serum ranges from 0.7 to 4.0 mg/ml. The assay measures human IgA in the 0.1-100 ng/ml range. Samples giving human IgA levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:100,000 to 1:800,000 dilution for normal human serum or plasma is suggested for best results. Human IgA will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human IgA primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of human IgA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human IgA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>The human IgA standard provided in this kit is calibrated against the WHO International Standard for Human Serum Immunoglobulins G, A and M (NIBSC Code 67/086).1 kit5695mol-innov2021
HU-IGDIgD was first identified in 1965, and like other immunoglobulins, exists as both secreted and membrane forms. Its level in plasma is low with a mean concentration of 30 ug/ml. IgD is present in large quantities on the surface membrane of a majority of human circulating B lymphocytes. IgD enhances humoral immune responses through its induction of IgD-receptor expression on T lymphocytes. Ref.: Coico RF, Siskind GW, Thorbecke GJ 1988. Immunol. Rev. 105:45. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.025 mg4165mol-innov2021
HU-IGDMIgD was first identified in 1965, and like other immunoglobulins, exists as both secreted and membrane forms. Its level in plasma is low with a mean concentration of 30 ug/ml. IgD is present in large quantities on the surface membrane of a majority of human circulating B lymphocytes. IgD enhances humoral immune responses through its induction of IgD-receptor expression on T lymphocytes. Ref.: Coico RF, Siskind GW, Thorbecke GJ 1988. Immunol. Rev. 105:45. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.  >95percent pure by SDS-PAGE.0.1 mg4930mol-innov2021
HU-IGEIgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. The affinity purified IgE reacted only with anti IgE and not with anti IgG, IgA, IgM or IgD by immunodiffusion and IEP techniques. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.1 mg10030mol-innov2021
HUIGEKTHuman Immunoglobulin E (IgE) is the least abundant immunoglobulin in serum and is predominately involved in the allergy response. IgE binds to allergens and triggers histamine release from mast cells and basophils. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. The sensitive quantitative measurement of total human IgE antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. Concentrations of 52 ng/ml in single donor plasma and 170 ng/ml in pooled plasma were found by in-house testing. 1 IU = 3.4 ng. The assay measures human IgE in the 1-500 ng/ml range. Samples giving human IgE levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:10 dilution for plasma is suggested for best results. Human IgE will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human IgE primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of human IgE in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human IgE and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The human IgE standard provided in this kit is calibrated against the WHO Reference Reagent for Human Serum Immunoglobulin E (NIBSC Code 75/502).</strong>1 kit3995mol-innov2021
HU-IGEMIgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior. The affinity purified IgE reacted only with anti IgE and not with anti IgG, IgA, IgM or IgD by immunodiffusion and IEP techniques. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.0.1 mg5950mol-innov2021
HU-IGG1In normal adult serum, the approximate percentage composition of IgG with respect to its subclasses is IgG1:65percent, Ig2:23percent, IgG3:6percent, and IgG4:6percent. Abnormal levels of one or more subclasses may be associated with autoimmune, anaphylatic and gut diseases, as well as with recurrent infection. Single arc by IEP against antisera to whole human serum and human IgG. No reaction to antisera to human IgA, IgD, IgE, or IgM. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg7140mol-innov2021
HU-IGG1MIn normal adult serum, the approximate percentage composition of IgG with respect to its subclasses is IgG1:65percent, Ig2:23percent, IgG3:6percent, and IgG4:6percent. Abnormal levels of one or more subclasses may be associated with autoimmune, anaphylatic and gut diseases, as well as with recurrent infection. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Single arc by IEP against antisera to whole human serum, human IgG, and human kappa. Indirect ELISA indicates IgG1 subclass. >95percent pure by SDS-PAGE.5.0 mg4845mol-innov2021
HU-IGG2IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria. Single arc by IEP against antisera to whole human serum and human IgG. No reaction to antisera to human IgA, IgD, IgE, or IgM. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg7140mol-innov2021
HU-IGG2MIgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Single arc by IEP against antisera to whole human serum, human IgG, and human kappa. Indirect ELISA indicates IgG2 subclass. >95percent pure by SDS-PAGE.5.0 mg5100mol-innov2021
HU-IGG3Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg7140mol-innov2021
HU-IGG4Prepared from normal plasma by affinity chromatography. IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with recurrent pyogenic infections. Prepared from normal plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.1.0 mg7140mol-innov2021
HUIGG4KTHuman immunoglobulin G subclass 4 (IgG4) is the least abundant IgG subclass in serum and is frequently induced by repeated allergen exposure. IgG4 does not have allotype variation and does not interact with complement component C1q. Clinically elevated serum IgG4 levels occur in a variety of conditions including the multi-organ fibro-inflammatory IgG4-related disease. The sensitive quantitative measurement of total human IgG4 antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not detect immunoglobulins of other classes or subclasses. The mean value of IgG4 in serum of healthy donors was found to be 1.04 mg/ml. The assay measures human IgG4 in the 0.5-500 ng/ml range. Samples giving human IgG4 levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:200,000-1:100,000 dilution for plasma and serum is suggested for best results. Human IgG4 in samples will bind to the biotinylated capture antibody which is bound to the avidin on the plate. After appropriate washing steps, horseradish peroxidase labeled polyclonal anti-human IgG antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of human IgG4. Color development is proportional to the concentration of IgG4 in the samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
HUIGGKTHuman Immunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in human serum. The sensitive quantitative measurement of total human IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. The concentration of IgG in normal human serum ranges from 5 to 12 mg/ml. The assay measures human IgG in the 0.2-200 ng/ml range. Samples giving human IgG levels above 200 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000 dilution for plasma and serum is suggested for best results. Human IgG will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-human IgG primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of human IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>The human IgG standard provided in this kit is calibrated against the WHO International Standard for Human Serum Immunoglobulins G, A and M (NIBSC Code 67/086).1 kit3995mol-innov2021
HU-IGMIgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE.5.0 mg4930mol-innov2021
HUIGMKTImmunoglobulin M (IgM) is the first immunoglobulin produced in the immune response and is the third most abundant immunoglobulin in serum. IgM is a disulfide-linked 970kDa pentamer that activates complement and is responsible for red blood cell agglutination. Each monomer consists of two mu heavy chains and two kappa or lambda light chains. The sensitive quantitative measurement of total human IgM antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The concentration of IgM in normal human serum ranges from 0.5 to 2.0 mg/ml. The assay measures human IgM in the 0.2-200 ng/ml range. Samples giving human IgM levels above 200 ng/ml should be diluted in blocking buffer before use. A 1:25,000 to 1:200,000 dilution for normal human serum or plasma is suggested for best results. Human IgM will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-human IgM primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of human IgM in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human IgM and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5695mol-innov2021
HU-IGM-LIgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. Purified from normal human plasma by affinity chromatography then lyophilized. Heavy chain isotype confirmed by rapid lateral flow isotyping kit. Prepared from plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original or desired volume, aliquot and freeze unused portion.5.0 mg4930mol-innov2021
HU-IGMMIgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/ml. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Single arc by IEP against antisera to whole human serum, human IgM, and human kappa. Not immunoreactive to antisera to human IgA, IgG, IgD, IgE, and lambda by IEP. >95percent pure by SDS-PAGE.5.0 mg4930mol-innov2021
HUPA3A108Monoclonal antibody directed to the N-terminal alpha (light) chain region of human uPA, which includes the Amino-terminal Fragment (ATF) region. IgG fraction purified by immobilized Protein G. Isotype IgG.1.0 mg7565mol-innov2021
HUPA3A108-FITCFITC labeled monoclonal antibody directed to the N-terminal alpha (light) chain region of human uPA, which includes the Amino-terminal Fragment (ATF) region. IgG fraction purified by immobilized Protein G. Isotype IgG.0.1 mg5185mol-innov2021
HUPA3G65Capture monoclonal antibody directed to the C-terminal beta (heavy) chain region of human uPA, which includes the active site. IgG fraction purified by immobilized Protein G. Isotype IgG.1.0 mg7565mol-innov2021
HUPA3G65-FITCFITC labeled monoclonal antibody directed to the C-terminal beta (heavy) chain region of human uPA, which includes the active site. IgG fraction purified by immobilized Protein G. Isotype IgG.0.1 mg5185mol-innov2021
HUPA-IImmobilized human two-chain HMW urokinase is ideal for the controlled activation of plasminogen to plasmin. After the activation is complete, the resin is simply removed and the reaction is quenched. May be used to immunopurify monoclonal and polyclonal antibodies directed against human urokinase. May be used repeatedly.1.0 ml9860mol-innov2021
HUPAKTUrokinase plasminogen activator (uPA), along with its receptor uPAR, is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion and migration. Clinical studies have indicated that high uPA levels may elevate the risk for tumor invasion and metastasis. Increased expression and activity can exert potent arthritogenic properties in rheumatoid arthritis patients. Increased uPA activity may be an implication for the pathophysiology of endometriosis. The sensitive quantitative measurement of functionally active human uPA in plasma and other biological fluids is easily performed with this 96 well strip format ELISA kit. The mean value of uPA in healthy donors was found to be 1.1 ng/ml. The assay measures active uPA in the 0.1-50 ng/ml range.  Samples giving human uPA levels above 50 ng/ml should be diluted in blocking buffer before use. Samples of human plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation as platelets can release PAI-1, which in turn could potentially form a complex with active uPA. Serum and cell culture media at neutral pH may also be used. Functionally active uPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Inactive or complexed uPA will not bind to the PAI-1 and will not be detected by the assay. This kit does not cross react with mouse uPA.</b> After appropriate washing steps, anti-human uPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active uPA in the samples. A standard calibration curve is prepared using dilutions of purified uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8075mol-innov2021
HUPAKT-TOTUrokinase plasminogen activator (uPA), along with its receptor uPAR, is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion and migration. Clinical studies have indicated that high uPA levels may elevate the risk for tumor invasion and metastasis. Increased expression and activity can exert potent arthritogenic properties in rheumatoid arthritis patients. Increased uPA activity may be an implication for the pathophysiology of endometriosis. The sensitive quantitative measurement of total human uPA antigen in plasma, serum, culture media or tissue extract samples is easily performed with this 96 well strip format ELISA kit. The concentration of uPA antigen in human plasma has been reported to be 3.5 ng/ml. The assay measures total uPA in the 0.1-50 ng/ml range.  Samples giving human uPA levels above 50 ng/ml should be diluted in blocking buffer before use. Human uPA will bind to the capture antibody coated on the microtiter plate. <b>Free and complexed uPA will be detected by the assay.</b> After appropriate washing steps, anti-human uPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of human uPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<font color=red><br><br>1 kit8075mol-innov2021
HUPA-PLATE96 well plate with 8 removable strips coated with native human Urokinase (uPA) at 100 ul/well and blocked with 300 ul/well. Ideal for irreversible binding of active Plasminogen Activator Inhibitor (PAI-1) for functional ELISA experiments. Human uPA forms a covalent complex with PAI-1 of all species including human, mouse, rat, porcine and rabbit.5 plates3485mol-innov2021
HU-SIGASecretory Immunoglobulin A is the primary immunoglobulin on most mucosal surfaces. SigA is a polypetide complex made up of two IgA monomers, a connecting J chain, and the secretory component. Located on mucosal surfaces, SigA provides protection by preventing invasion of pathogens. No reaction by IEP with antiserum to human Albumin, IgD, IgE, IgG, IgM and Lactoferrin. Prepared from human milk shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.5.0 mg7310mol-innov2021
HVLDLIn a normal fasting individual, VLDL concentrations range from 0.5 - 2.0 g/L. VLDL transports triglycerides synthesized by the liver to sites of energy storage and utilization. Purity: single arc by IEP against antisera to whole human serum. Essentially free of other plasma lipoproteins as determined by electrophoresis using Fat Red 7B stain for lipids and Coomassie Blue for proteins. >95percent of total lipoprotein content by electrophoresis. Prepared from fresh, non-frozen plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Do NOT freeze this product.1.0 mg5525mol-innov2021
HVNPrepared from fresh human plasma using non-denaturing chromatography.0.5 mg15215mol-innov2021
HVN1D144Inhibitory monoclonal antibody produced in mouse. This antibody blocks smooth muscle and endothelial cell adhesion to vitronectin. Does not cross-react with mouse. IgG fraction purified by immobilized Protein A.1.0 mg8670mol-innov2021
HVN1E934ELISA: Monomeric and multimeric human vitronectin<br> 
WB: Non-reduced monomeric vitronectin<br> 
Monoclonal antibody produced in mouse. Cross reacts with bovine vitronectin and does not cross react with mouse vitronectin. IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
HVN1H820ELISA: Monomeric and multimeric human vitronectin<br>
WB: Non-reduced monomeric vitronectin<br>
Monoclonal antibody produced in mouse. Does not cross-react with mouse. IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
HVN2C323WB: Reduced and non-reduced monomeric vitronectin<br>
ELISA: Monomeric vitronectin only<br>
Monoclonal antibody produced in mouse. Does not cross-react with mouse. IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
HVN4A132WB: Reduced and non-reduced monomeric vitronectin<br>
ELISA: Not suitable<br>
Monoclonal antibody produced in mouse. Does not cross-react with mouse. IgG fraction purified by immobilized Protein A.
1.0 mg7990mol-innov2021
HVN-BIOPrepared from fresh human plasma using non-denaturing chromatography, then biotin labeled at primary amines.0.1 mg9860mol-innov2021
HVNKT-TOTVitronectin is an abundant plasma glycoprotein that helps regulate coagulation, fibrinolysis, complement activation, and cell adhesion. Vitronectin binds to glycosaminoglycans, collagen, plasminogen and urokinase receptors. It also may control the clearance of vascular thrombi by binding and stablilizing PAI-1. In binding PAI-1, it extends the lifetime of active PAI-1. Vitronectin may also be involved in the regulation of bone metabolism. The sensitive quantitative measurement of total human vitronectin antigen in plasma, serum, culture media or tissue extract samples is easily performed with this 96 well strip format ELISA kit.  Using this assay, values for plasma vitronectin in normal individuals were determined to be 127.5 +/- 13.1 ug/ml. Vascular samples from the saphenous vein, mammary artery, and human adipose tissue were also assayed for vitronectin, with values ranging from 5-40 ug/mg. The assay measures total vitronectin in the 0.5-100 ng/ml range.  Samples giving human vitronectin levels above 100 ng/ml should be diluted in blocking buffer before use. Human vitronectin will bind to the capture antibody coated on the microtiter plate. <b>This kit does not cross react with mouse vitronectin.</b>After appropriate washing steps, anti-human vitronectin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of human vitronectin in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified human vitronectin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Human-Vitronectin-Antigen-Capture-Plate>Human Vitronectin Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 Kit8075mol-innov2021
HVN-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to human Vitronectin at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of human vitronectin antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
HVN-UPrepared from fresh human plasma using urea as a denaturant.0.1 mg3995mol-innov2021
HVN-U-BIOPrepared from fresh human plasma using urea as a denaturant, then biotin labeled at primary amines.0.1 mg5950mol-innov2021
HVWFvWF is prepared from citrated human plasma using a combination of chromotographic procedures. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This preparation is >95percent pure as judged by SDS-PAGE under reducing conditions, and consists of large multimers as determined by electrophoresis in SDS/agarose gels. Molecular weight under native conditions ranges from 520 kDa (dimer) to >10,000 kDa (multimers). Protein concentration determined by total protein assay. Required thawing procedure: Remove the sample from freezer and place in a 37 degree celsius water bath. Allow the vial to remain in the water bath for 2 minutes without agitation following complete disappearance of the frozen material. Remove sample and gently mix with a pipet or by gentle agitation. If precipitate is observed, place in water bath for an additional 2-3 minutes then mix again.0.1 mg7480mol-innov2021
HVWF-F8vWF is prepared from citrated human plasma using a combination of chromotographic procedures. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests. This preparation is >95percent pure as judged by SDS-PAGE under reducing conditions, and consists of large multimers as determined by electrophoresis in SDS/agarose gels. Molecular weight under native conditions ranges from 520 kDa (dimer) to >10,000 kDa (multimers). Protein concentration determined by total protein assay. Required thawing procedure: Remove the sample from freezer and place in a 37 degree celsius water bath. Allow the vial to remain in the water bath for 2 minutes without agitation following complete disappearance of the frozen material. Remove sample and gently mix with a pipet or by gentle agitation. If precipitate is observed, place in water bath for an additional 2-3 minutes then mix again.0.1 mg10200mol-innov2021
HVWFKT-TOTvon Willebrand Factor (vWF) is a plasma glycoprotein that circulates as disulfide linked multimers ranging in size from 520 kDa dimers to greater than 20,000 kDa. Each 260 kDa 2,050 amino acid monomer binds one Factor VIII molecule protecting against proteolytic degradation and clearance. vWF also binds platelets and collagen and is required for platelet plug formation. ADAMTS13 cleaves vWF at vascular injury sites, in circulation, and anchored on the endothelial surface. Type 1 von Willebrand disease due to quantitative vWF deficiency is characterized by mild bruising and bleeding. The sensitive quantitative measurement of total human vWF antigen (VWF:Ag) in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. The concentration of vWF in normal human plasma is approximately 10.0 µg/ml. The normal range is 0.5-2 IU/ml with values less than 0.5 IU/ml indicating type 1 von Willebrand disease. The assay measures human vWF in the 0.5-500 ng/ml range. Samples giving human vWF levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:200-1:1,000 dilution for plasma or serum is suggested for best results. Human vWF will bind to the monoclonal capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated monoclonal anti human vWF primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared using dilutions of human vWF and is measured along with the test samples. Color development is proportional to the concentration of vWF in the samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
INFFRCKATA-FFRCK (Na-[(acetylthio) acetyl]-D-Phe-Phe-Arg-CH2Cl) and ATA-FPRCK (Na-[(acetylthio)acetyl]-D-Phe-Pro-Arg-CHCl2) are active-site specific labeling reagents for serine proteases. They are derivatized from irreversible peptide chloromethyl ketones and facilitate incorporation of a thioester moiety via alkylation of the catalytic site Histidine residue. Liberation of the free thiol group is accomplished by gentle treatment with hydroxylamine (NH2OH) following irreversible incorporation into the enzyme catalytic site. The free thiol then becomes a site for specific modifications with thiol-reactive probes such as iodoacetamide fluorescent probes. Many serine proteases in which free thiols are lacking may be specifically labeled at the active site by these reagents. Both ATA-FPRCK and ATA-FFRCK have been used to label thrombin with 5-(iodoacetamido) fluorescein (5-IAF). The probe was then effectively utilized to follow conformational changes in the catalytic domain of alpha-thrombin upon binding to the fragment 2 domain of prothrombin. In addition, quantitative equilibrium binding studies and investigations into the kinetics underlying the non-proteolytic activation of the zymogen plasminogen by streptokinase were characterized with 2-((4'-iodoacetamido) anilino) naphthalene-6-sulfonic acid (IAANS) labeled plasminogen by using the ATA-FFRCK reagent. References: 1. Bock, P. (1993) Method Enzymol. 222:478-503. 2. Bock, P. et al. (1996) J Biol. Chem. 271:1072-1080.0.1 mg5950mol-innov2021
INFPRCKATA-FFRCK (Na-[(acetylthio) acetyl]-D-Phe-Phe-Arg-CH2Cl) and ATA-FPRCK (Na-[(acetylthio)acetyl]-D-Phe-Pro-Arg-CHCl2) are active-site specific labeling reagents for serine proteases. They are derivatized from irreversible peptide chloromethyl ketones and facilitate incorporation of a thioester moiety via alkylation of the catalytic site Histidine residue. Liberation of the free thiol group is accomplished by gentle treatment with hydroxylamine (NH2OH) following irreversible incorporation into the enzyme catalytic site. The free thiol then becomes a site for specific modifications with thiol-reactive probes such as iodoacetamide fluorescent probes. Many serine proteases in which free thiols are lacking may be specifically labeled at the active site by these reagents. Both ATA-FPRCK and ATA-FFRCK have been used to label thrombin with 5-(iodoacetamido) fluorescein (5-IAF). The probe was then effectively utilized to follow conformational changes in the catalytic domain of alpha-thrombin upon binding to the fragment 2 domain of prothrombin. In addition, quantitative equilibrium binding studies and investigations into the kinetics underlying the non-proteolytic activation of the zymogen plasminogen by streptokinase were characterized with 2-((4'-iodoacetamido) anilino) naphthalene-6-sulfonic acid (IAANS) labeled plasminogen by using the ATA-FFRCK reagent. References: 1. Bock, P. (1993) Method Enzymol. 222:478-503. 2. Bock, P. et al. (1996) J Biol. Chem. 271:1072-1080.0.1 mg5950mol-innov2021
KNG15C7Mouse monoclonal antibody to human kininogen. Detects kininogen under non-reducing conditions. IgG fraction purified by immobilized Protein G. Clone 15C7-4F7, isotype IgG1.0.1 mg3400mol-innov2021
KNG15G5Mouse monoclonal antibody to human kininogen. Detects kininogen under non-reducing conditions. IgG fraction purified by immobilized Protein A. Clone 15G5-A11, isotype IgG2b.0.1 mg3400mol-innov2021
KNG15G5-BIOBiotin labeled mouse monoclonal antibody to human kininogen. Detects kininogen under non-reducing conditions. IgG fraction purified by immobilized Protein A. Clone 15G5-A11, isotype IgG2b.0.1 mg5185mol-innov2021
KNG16E4Mouse monoclonal antibody to human kininogen. Strongly blots kininogen under non-reducing and reducing conditions. Binding epitope is on the light chain of kininogen. IgG fraction purified by immobilized Protein G. Clone 16E4-H1, isotype IgG1.0.1 mg3400mol-innov2021
KNG17A12Mouse monoclonal antibody to human kininogen. Strongly blots kininogen under non-reducing and reducing conditions. Binding epitope is on the light chain of kininogen. IgG fraction purified by immobilized Protein G. Clone 17A12-F12, isotype IgG1.0.1 mg3400mol-innov2021
KNG17E10Mouse monoclonal antibody to human kininogen. Strongly blots kininogen under non-reducing and reducing conditions. Binding epitope is on the light chain of kininogen. IgG fraction purified by immobilized Protein G. Clone 17E10-G9, isotype IgG2b.0.1 mg3400mol-innov2021
KNG17E10-BIOBiotin labeled mouse monoclonal antibody to human kininogen. Strongly blots kininogen under non-reducing and reducing conditions. Binding epitope is on the light chain of kininogen. IgG fraction purified by immobilized Protein G. Clone 17E10-G9, isotype IgG2b.0.1 mg5185mol-innov2021
KNG17F8Mouse monoclonal antibody to human kininogen. Detects kininogen under non-reducing conditions. IgG fraction purified by immobilized Protein A. Clone 17F8-F10, isotype IgG1.0.1 mg3400mol-innov2021
LADDER-HThis High Range DNA Ladder features bands ranging from 500bp-10kb. It is supplied at a concentration of 130 ug/ml and is premixed with MantisGreen dual-color loading dye. The blue dye runs at 4kb and the yellow dye runs under 25bp. The High Range DNA Ladder contains DNA bands of 0.5, 0.6, 0.8, 1, 1.5, 2, 3, 4, 5, 6, 8, and 10kb. We recommend loading 5 ul per agarose gel lane.0.5 ml1785mol-innov2021
LADDER-LThis Low Range DNA Ladder features bands ranging from 50bp-1kb. It is supplied at a concentration of 120 ug/ml and is premixed with MantisGreen dual-color loading dye. The blue dye runs at 4kb and the yellow dye runs under 25bp. The Low Range DNA Ladder contains DNA bands of 50, 75, 100, 150, 200, 300, 400, 500, 600, 800, and 1000bp. We recommend loading 5 ul per agarose gel lane.0.5 ml1785mol-innov2021
LADDER-MThis Mid Range DNA Ladder features bands ranging from 100bp-3kb. It is supplied at a concentration of 130 ug/ml and is premixed with MantisGreen dual-color loading dye. The blue dye runs at 4kb and the yellow dye runs under 25bp. The Mid Range DNA Ladder contains DNA bands of 100, 150, 200, 300, 400, 500, 600, 800, 1000, 1500, 2000, and 3000bp. We recommend loading 5 ul per agarose gel lane.0.5 ml1785mol-innov2021
MA-124K1Inhibitory monoclonal antibody to rat PAI-1. It has recently been reported that binding of this antibody to rat PAI-1 inhibits rat PAI-1 activity and simultaneously increases the binding of inactive PAI-1 to vitronectin. This antibody demonstrates low affinity for, and inhibition of, glycosylated rat PAI-1. Can be used as a capture antibody in ELISA assays. Purified by immobilized Protein A. IgG1k class.1.0 mg15215mol-innov2021
MA-1H10Monoclonal antibody produced in mouse. Useful for ELISA and western blot under non-reducing conditions. Binds to an epitope on the C-terminus of VLDL receptor ligand binding domain (amino acids 191-355, UniProtKB: locus VLDLR_HUMAN, accession P98155) and blocks apoE4 binding. Purified by immobilized Protein A. IgG1 class.<br>
References:<br>
Functional domains of the very low density lipoprotein receptor: molecular
analysis of ligand binding and acid-dependent ligand dissociation
mechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 (1999).<br>
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 (2005).
1.0 mg8585mol-innov2021
MA-1H5Monoclonal antibody produced in mouse. Useful for ELISA. Binds to an epitope on the C-terminus of VLDL receptor ligand binding domain (amino acids 191-355, UniProtKB: locus VLDLR_HUMAN, accession P98155) and blocks apoE4 binding. Purified by immobilized Protein A. IgG1 class.<br> 
References:<br> 
Functional domains of the very low density lipoprotein receptor: molecular analysis of ligand binding and acid-dependent ligand dissociation mechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 (1999).<br> 
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 (2005).
1.0 mg8585mol-innov2021
MA2AP-FLAGRecombinantly produced in insect cells and purified by FLAG affinity. Contains a Flag tag (DYKDDDDK) at N terminus for purification.0.1 mg8670mol-innov2021
MA2AP-HISRecombinantly produced in insect cells and purified by chelated metal affinity chromatography. Contains a 6X-Histidine tag at N terminus for purification.0.1 mg5695mol-innov2021
MA2APKT-TOTAlpha-2-antiplasmin is the major circulating inhibitor of plasmin. It plays a role in the regulation of intravascular fibrinolysis. Decreased levels of alpha-2-antiplasmin may play an important role in the increased capacity of the fibrinolytic function and may be beneficial in the treatment of thrombotic diseases, acute pulmonary embolism, and hepatic repair. The sensitive quantitative measurement of total mouse alpha-2-antiplasmin antigen in plasma or serum samples is easily performed with this 96 well strip format ELISA kit. The normal mouse concentration of antiplasmin is 86 ug/ml in plasma. The assay measures total antiplasmin in the 0.1-100 ng/ml range. Samples giving mouse antiplasmin levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:10,000-20,000 dilution for plasma is suggested for best results. Mouse antiplasmin will bind to the capture antibody coated onto a micro titer plate. <b>Free and complexed antiplasmin will bind to the plate and will be detected by the assay.</b> After appropriate washing steps, biotin labeled anti-mouse antiplasmin primary antibody binds to the antiplasmin. Excess antibody is washed away, and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of antiplasmin in the samples. A standard calibration curve is prepared using dilutions of purified antiplasmin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>1 kit8415mol-innov2021
MA-31C9Non-inhibitory monoclonal antibody to human PAI-1 which does not affect binding with vitronectin. Can be used as a capture antibody in ELISA assays. Purified by immobilized Protein A. IgG1k class.1.0 mg15215mol-innov2021
MA-32K3Non-inhibitory monoclonal antibody to rat PAI-1. Purified by immobilized Protein A. IgG1k class.1.0 mg15215mol-innov2021
MA-33B8Inhibitory monoclonal antibody to human and rabbit PAI-1. It binds to a conformational epitope on PAI-1 converting it into the latent form. Currently being studied as a potential therapeutic agent in animal studies. Purified by immobilized Protein A. IgG1k class.1.0 mg15215mol-innov2021
MA-33H1F7Inhibitory monoclonal antibody to human and mouse PAI-1. It binds to an epitope localized to the F-Helix of PAI-1. The PAI-1/mab complex becomes a substrate rather than an inhibitor of its target proteinases tPA and urokinase. Currently being studied as a potential therapeutic agent in animal models. Purified by immobilized Protein A. IgG1 class.1.0 mg15215mol-innov2021
MA-5A6Monoclonal antibody to human 85 kDa light chain of LRP. Cross-reacts with rabbit and mouse LRP. Stimulates cellular-mediated uptake of alpha 2 macroglobulin trypsin complex by LRP1. Use WI-38 fibroblast as positive control and human umbilical vein endothelial cells (HUVEC) as negative control. Purified by immobilized Protein A. IgG2b kappa class.1.0 mg8585mol-innov2021
MA-5A6-BIOBiotin labeled monoclonal antibody to human 85 kDa light chain of LRP. Purified by immobilized Protein A. IgG2b kappa class.0.1 mg3995mol-innov2021
MA-5A6-FITCFluorescein labeled monoclonal antibody to human 85 kDa light chain of LRP. Purified by immobilized Protein A. IgG2b kappa class.0.1 mg3995mol-innov2021
MA-5F3Monoclonal antibody produced in mouse. Useful for ELISA and western blot under reducing and non-reducing conditions. Binds to an epitope on the VLDL receptor ligand binding domain (amino acids 31-355, UniProtKB: locus VLDLR_HUMAN, accession P98155). Purified by immobilized Protein A. IgG1 class.<br>
References:<br>
Functional domains of the very low density lipoprotein receptor: molecular
analysis of ligand binding and acid-dependent ligand dissociation
mechanisms. Mikhailenko I et al. Journal of Cell Science 112, 3269-3281 (1999).<br>
The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor. Ruiz J et al. Journal of Lipid Research 46, 1721-1731 (2005).
1.0 mg8585mol-innov2021
MA-7F1Monoclonal antibody to human RAP. No cross-reaction with rabbit or mouse RAP. IgG fraction purified by immobilized Protein A. Isotype IgG1.1.0 mg8585mol-innov2021
MA-7F1-BIOBiotin labeled monoclonal antibody to human RAP. Purified by immobilized Protein A. IgG1 class.0.1 mg3995mol-innov2021
MA-7F1-FITCFluorescein labeled monoclonal antibody to human RAP. Purified by immobilized Protein A. IgG1 class.0.1 mg3995mol-innov2021
MA-8B8Monoclonal antibody to human 85 kDa light chain of LRP. Cross-reacts with rabbit LRP. Use WI-38 fibroblast as positive control and human umbilical vein endothelial cells (HUVEC) as negative control. Purified by immobilized Protein A. IgG1 class.1.0 mg8585mol-innov2021
MA-8B8-BIOBiotin labeled monoclonal antibody to human 85 kDa light chain of LRP. Purified by immobilized Protein A. IgG1 class.0.1 mg3995mol-innov2021
MA-8B8-FITCFluorescein labeled monoclonal antibody to human 85 kDa light chain of LRP. Purified by immobilized Protein A. IgG1 class.0.1 mg3995mol-innov2021
MA-8G1Monoclonal antibody to human 515 kDa heavy chain of LRP. Useful marker for the characterization of a subset of myelo-monocytic subtypes of chronic and acute leukemia (CD91). Blocks cellular-mediated uptake of alpha 2 macroglobulin trypsin complex by LRP1. Use WI-38 fibroblast as positive control and human umbilical vein endothelial cells (HUVEC) as negative control. Purified by immobilized Protein A. IgG1kappa class.1.0 mg8585mol-innov2021
MA-8G1-BIOBiotin labeled monoclonal antibody to human 515 kDa heavy chain of LRP. Purified by immobilized Protein A. IgG1k class.0.1 mg3995mol-innov2021
MA-8G1-FITCFluorescein labeled monoclonal antibody to human 515 kDa heavy chain of LRP. Purified by immobilized Protein A. IgG1k class.0.1 mg3995mol-innov2021
MA-8H9D4Inhibitory monoclonal antibody to human and porcine PAI-1. Does not cross-react with mouse or rat. It binds to the axis connecting Arg300, Gln303 and Arg305 interfering with the final step of covalent complex formation. MA-8H9D4 shifts the reaction to the substrate pathway without decreasing the rate-limiting constant for reactive center loop insertion by tPA. IgG fraction purified by immobilized Protein A. Clone 8H9D4, isotype IgG1.1.0 mg16915mol-innov2021
MA-HFIIClone number AHP-5013. Reactive to: Human prothrombin, prethrombin-1, fragment 2, meizothrombin. Does not recognize mouse thrombin by western blot. Inhibits clotting and prothrombin activation. Clotting inhibition was determined by incubating the antibody with human normal pooled plasma followed by a PT assay. Extension of the clot time reflects inhibition of the clotting. The inhibition of the prothrombin activation was determined in prothrombinase reactions using purified clotting factors and DAPA as a substrate for thrombin. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG2a.0.1 mg3740mol-innov2021
MA-HPC-1Clone number AHPC-5071. Recognizes human protein C and activated protein C. Partial calcium dependence. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG1.0.1 mg3740mol-innov2021
MA-HPC-2Clone number AHPC-5072. Recognizes human protein C. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG2b.0.1 mg3740mol-innov2021
MA-HPS-2Clone number AHPS-5092. Reactive to: Human protein S. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG1.0.1 mg3740mol-innov2021
MA-HTAFI-1Clone number AHTAFI-5024. Reactive to: Human TAFI, activated TAFI. Inhibits TAFI activation and inhibits activated TAFI. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG1.0.1 mg3740mol-innov2021
MA-HTAFI-2Clone number AHTAFI-5026. Reactive to: Human TAFI. Inhibits TAFI activation. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG1.0.1 mg3740mol-innov2021
MA-HTAFI-3Clone number AHTAFI-5065. Reactive to: Human TAFI, activated TAFI. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG3.0.1 mg3740mol-innov2021
MA-HTAFI-4Clone number AHTAFI-5081. Reactive to: Human TAFI. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG2b.0.1 mg3740mol-innov2021
MA-HTFClone number AHTF-5264. Reactive to: Human Tissue Factor. Does not react with mouse Tissue Factor. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG.0.1 mg3740mol-innov2021
MA-HTFPIClone number AHTFPI-5138. Reactive to: Human Tissue Factor Pathway Inhibitor. Binds to an epitope on the N-terminus of TFPI. IgG fraction purified by conventional chromatography. Mouse monoclonal of isotype IgG.0.1 mg3740mol-innov2021
MA-HTHROMClone number AHT-5020. Reactive to: Human thrombin, thrombin-ATIII complex, thrombin-PPACK. Extends the clotting time of normal human plasma as determined by PT assay. Does not react with prothrombin except at very high concentrations. IgG fraction purified by immobilized Protein G. Mouse monoclonal of isotype IgG1.0.1 mg3740mol-innov2021
MA-MFIX-1Clone number AMIXA-9041. Detects Factor IX and Factor IXa in ELISA, Factor IX and Factor IXa heavy chain reduced and non-reduced in western blot, does not cross react with human Factor IX and Factor IXa. IgG fraction purified by conventional chromatography. Host rat.0.1 mg4165mol-innov2021
MA-MFIX-2Clone number AMIXA-9042. Detects Factor IX and Factor IXa in ELISA, Factor IX and Factor IXa non-reduced in western blot, does not cross react with human Factor IX and Factor IXa. IgG fraction purified by conventional chromatography. Host rat.0.1 mg4165mol-innov2021
MA-MFVIIClone number AMVII-9031. Detects recombinant mouse Factor VII and Factor VIIa in ELISA, recombinant mouse Factor VII and Factor VIIa non-reduced in western blot, does not cross react with human Factor VII and Factor VIIa. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MFVIIIClone number AMVIII-9035. Detects recombinant mouse Factor VIII in ELISA and recombinant mouse Factor VIII non-reduced in western blot.  Native mouse and human Factor VIII have not been tested. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MFX-1Clone number AMX-9050. Detects Factor X and Factor Xa in ELISA, Factor X and Factor Xa heavy chain reduced and non-reduced in western blot, cross reacts with human Factor X and Factor Xa. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MFX-2Clone number AMX-9051. Detects Factor X in ELISA, Factor X heavy chain non-reduced in western blot. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MPC-1Clone number AMPC-9071. Detects Protein C in ELISA, Protein C reduced and non-reduced in western blot, inhibits Protein C activation in rabbit thrombomodulin and Protac assays. Does not cross react with activated Protein C or human Protein C. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MPC-2Clone number AMPC-9072. Detects Protein C and APC in ELISA, Protein C reduced and non-reduced in western blot. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MPGClone number AMPG-9130. Detects plasminogen and plasmin in ELISA, plasmin non-reduced and plasminogen reduced and non-reduced in western blot. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MA-MPTClone number AMP-9013. Detects prothrombin in ELISA, prothrombin non-reduced in western blot, does not cross react with thrombin. IgG fraction purified by immobilized Protein G. Host rat.0.1 mg4165mol-innov2021
MAP25C3Non-inhibitory monoclonal antibody produced in an alpha-2-antiplasmin knockout mouse. IgG fraction purified by immobilized Protein A. Clone 25C3, isotype IgG.<br> 
References:<br> 
Depletion of circulating a2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization. Nagai M et al. Blood 97, 3086-3092 (2001).
1.0 mg10115mol-innov2021
MAP27C9Inhibitory monoclonal antibody produced in an alpha-2-antiplasmin knockout mouse. Neutralizes mouse antiplasmin as determined by in vitro chromogenic plasmin activity assay. IgG fraction purified by immobilized Protein A. Clone 27C9, isotype IgG.<br> 
References:<br> 
Depletion of circulating a2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization. Nagai M et al. Blood 97, 3086-3092 (2001).
1.0 mg10115mol-innov2021
MAP4H9Inhibitory monoclonal antibody produced in an alpha-2-antiplasmin knockout mouse. Neutralizes 60 percent of mouse antiplasmin in equimolar mixtures as determined by in vitro chromogenic plasmin activity assay. IgG3K fraction purified by immobilized Protein A. Clone 4H9, isotype IgG3 kappa.<br> 
References:<br> 
Depletion of circulating a2-antiplasmin by intravenous plasmin or immunoneutralization reduces focal cerebral ischemic injury in the absence of arterial recanalization. Nagai M et al. Blood 97, 3086-3092 (2001).
1.0 mg10115mol-innov2021
MATFAmino terminal fragment of mouse urokinase. The amino terminal fragment (ATF) of uPA is purified from auto-catalytic digestion of recombinant mouse urokinase produced in insect cells. ATF contains the Kringle and Epidermal Growth Factor domains and is separated from LMW uPA by cleavage at the Lys136-Lys137 bond.0.05 mg5695mol-innov2021
MATF-AF750Amino terminal fragment of mouse urokinase. Labeled with Alexa Fluor 750 at primary amines (Abs: 753, Em: 782).0.05 mg8670mol-innov2021
MATIIIPrepared from fresh mouse plasma using several chromatographic steps.1.0 mg7735mol-innov2021
MC1INH-HISMouse C1 Inhibitor (also known as plasma protease C1 inhibitor, C1 esterase inhibitor, C1-inhibiting factor, C1-INH, and C1INA) is a single chain glycosylated serine protease inhibitor (serpin) which inhibits C1, C1r, C1s, plasma kallikrein, Factors XIa. XIIa, and plasmin. C1 Inhibitor is present in human plasma at 16-33 mg per 100 ml and is involved in the regulation of the contact and complement systems. Recombinantly produced in insect cell culture and purified by chelated metal affinity chromatography. Contains a 10X-Histidine tag at C terminus for purification. Fully active and &gt;95percent pure by SDS-PAGE.0.1 mg6885mol-innov2021
MC1INH-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving plasma protease C1 inhibitor, also known as C1 esterase inhibitor, C1-inhibiting factor, C1-INH, and C1IN. Collected from homozygous C1 Inhibitor knockout mice, anticoagulated with sodium citrate and flash frozen. Collected from male mice. Female mouse plasma is also available. Freshly collected C1 Inhibitor knockout mouse organs are also available. C1 Inhibitor knockout mice are an established research model for hereditary angioedema (HAE). Mice homozygous for this mutation develop normally and are viable and fertile with increased vascular permeability.0.05 ml3400mol-innov2021
MC3KTComplement Component 3 (C3), the most abundant serum complement component, is a disulfide-linked 185kDa 1,637 amino acid glycoprotein which supports the classical, alternative, and lectin pathways of complement activation. C3 is proteolytically activated by C3-convertase to the anaphylatoxin C3a and the opsonizing agent C3b. Serum concentrations of C3 are increased during acute and chronic inflammation such as rheumatoid arthritis, and are decreased due to increased consumption or autoimmune disorders such as systemic lupus erythematosus. The sensitive quantitative measurement of total mouse C3 antigen in plasma and serum is easily performed with this 96 well strip format ELISA kit. C3 is present in normal mouse plasma at average concentrations of 0.54-1.0 mg/ml. The assay measures total mouse C3 in the 0.1-100 ng/ml range. Samples giving mouse C3 levels above 100 ng/ml should be diluted in blocking buffer before use. For best results, dilute plasma and serum samples 1:100,000 to 1:1,000,000. Mouse C3 will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, HRP labeled anti-mouse C3 primary antibody binds to the captured protein. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of C3 in the samples. A standard calibration curve is prepared using dilutions of purified C3 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6375mol-innov2021
MCRPKTC-reactive protein (CRP) is an acute phase reactant which is elevated in plasma in response to increased interleukin-6 induced by inflammation, infection and tissue injury. CRP is expressed mainly in the liver and activates the complement pathway following calcium-dependent binding to phosphocholine on apoptotic, necrotic and microbial cells. The sensitive quantitative measurement of total mouse CRP antigen in plasma and other biological fluids is easily performed with this 96 well strip format ELISA kit. This kit has been validated for measurement of CRP in C57 mouse plasma (20 ug/ml), Balb/C mouse plasma (3.5 ug/ml), and CD1 mouse plasma (7.2 mg/ml). The assay measures CRP antigen in the 0.02-2 ng/ml range. Samples giving mouse CRP levels above 2 ng/ml should be diluted in blocking buffer before use. For best results, dilute plasma samples 1:25,000 to 1:50,000. Mouse CRP will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse CRP primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of CRP in the samples. A standard calibration curve is prepared using dilutions of purified CRP and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5185mol-innov2021
MEPO-FCErythropoietin (EPO) is a glycoprotein hormone related to Thrombopoietin which stimulates erythrocyte formation by inhibiting apoptosis of early erythroid 
precursors. Mouse EPO (Ala27-Arg192) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured in a proliferation assay with human TF-1 erythroleukemia cells (Kitamura et al. (1989) J. Cell Physiol. 140:323). The ED50 for this activity is typically < 5 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
<img src=/img/mouse-epo.jpg><br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
0.1 mg5185mol-innov2021
MFBGNPrepared from fresh mouse plasma using several chromatographic steps.  Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg1445mol-innov2021
MFBGN-FITCMouse fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh mouse plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg8755mol-innov2021
MFBGN-FNPrepared from fresh mouse plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Fibronectin depleted by gelatin affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg8755mol-innov2021
MFBGNKTFibrinogen is a soluble glycoprotein that circulates in the blood and is converted to insoluble fibrin by thrombin in the final step of the coagulation cascade. Hepatic expression of fibrinogen increases two to four hundred fold during the acute phase response to infection or inflammation. Elevated fibrinogen levels are correlated with cardiovascular disease and atherosclerosis. The sensitive quantitative measurement of total mouse fibrinogen antigen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. The concentration of fibrinogen in normal mouse plasma ranges from 1.4-2.1 mg/ml and varies by strain and diet. The assay measures total mouse fibrinogen in the 3.125-800 ng/ml range. Samples giving mouse fibrinogen levels above 800 ng/ml should be diluted in 1X diluent before use. A 1:100,000 to 1:1,000,000 dilution for plasma or serum is suggested for best results. Mouse fibrinogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse fibrinogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of fibrinogen in the samples. A standard calibration curve is prepared using dilutions of purified fibrinogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-Fibrinogen-Antigen-Capture-Plate>Mouse Fibrinogen Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Avidin-HRP-Labeled>Avidin-HRP</a>
1 kit5185mol-innov2021
MFBGN-SNormal mouse plasma clots are dissociated using non-denaturing conditions in which non fibrin bound plasma proteins are removed. The soluble fibrin clot is then stored under acidic conditions. The soluble fibrin will reassemble into an insoluble clot when pH is restored to neutral (e.g. by adding one-tenth volume of 10X PBS to the soluble fibrin). SDS-PAGE shows partially crosslinked fibrin with no observable free alpha, beta or gamma chain subunits. No detectable thrombin or plasmin activity is observed in the final product.1.0 mg5015mol-innov2021
MFBGN-TOT-PLATE96 well plate with 8 removable strips coated with affinity purified polyclonal antibody to mouse Fibrinogen at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of mouse fibrinogen antigen for sandwich style ELISA experiments. Cross reacts with rat fibrinogen.1 plate2210mol-innov2021
MFBNPrepared from fresh mouse plasma. Ideal reagent for tissue culture studies and protein-protein interactions. Thaw the fibronectin by placing the vial in a 37 C water bath and leaving it undisturbed until completely thawed. Do not disturb the vial at any time during the thawing process. If the vial is disturbed or removed prior to complete thawing, the fibronectin will form a gel and be unusable. Mix very gently with pipette after thawing. Vortexing, excessive agitation, repeated freezing and thawing of  fibronectin are not recommended.1.0 mg6035mol-innov2021
MFIIMouse prothrombin is prepared from fresh frozen mouse plasma. Purity is determined by SDS-PAGE analysis.0.1 mg3740mol-innov2021
MFIX-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving Factor IX. Collected from homozygous Factor IX knockout mice, anticoagulated with sodium citrate and flash frozen. Collected from female mice. Male mouse plasma is also available. Freshly collected Factor IX knockout mouse organs are also available. Factor IX knockout mice are an established research model for hemophilia B. Mice homozygous for this mutation develop normally and are viable and fertile. aPTT is greatly increased but PT is normal compared to wild type mice.0.05 ml3400mol-innov2021
MFXFactor X is isolated from fresh frozen plasma by a combination of conventional techniques and immunoaffinity chromatography. Purity is determined by SDS-PAGE analysis and activity is measured in a factor X clotting assay.0.1 mg11560mol-innov2021
MFXAFactor Xa is prepared by activating purified factor X with the factor X activator isolated from Russell's viper venom. Factor Xa is purified from the activation mixture by chromatography over benzamidine-Sepharose. Purity is determined by SDS-PAGE analysis and activity is measured in a factor Xa clotting assay and/or chromogenic substrate assay.0.05 mg8925mol-innov2021
MFX-HISRecombinantly produced in HEK cell culture and purified by conventional and chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification. Fully activatable to FXa by Russell's Viper Venom. Complements for Factor X in human deficient plasma clotting assays.0.1 mg4845mol-innov2021
MFXIIRecombinant insect cell derived mouse Factor XII is a single chain glycoprotein purified by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease (Factor &#945;-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Custom mutants of Factor XII are also available, please contact us for more details.0.05 mg5695mol-innov2021
MFXIIAMouse Factor &#945;-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system of blood coagulation. Recombinant insect cell derived mouse Factor &#945;-XIIa is manufactured by autoactivation of recombinant mouse Factor XII with Dextran Sulfate and re-purified to remove the activator. >95percent activation is observed on SDS-PAGE. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Custom mutants of Factor XII are also available, please contact us for more details.0.05 mg6885mol-innov2021
MFXII-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving Factor XII. Collected from homozygous Factor XII knockout mice, anticoagulated with sodium citrate and flash frozen. Collected from male mice. Female mouse plasma is also available. Freshly collected Factor XII knockout mouse organs are also available. Mice homozygous for this mutation develop normally and are viable and fertile. aPTT is greatly increased but PT is normal compared to wild type mice. Factor XII null mice were shown to be protected from ischemic stroke in a transient middle cerebral artery occlusion animal model of stroke.<br> 
References:<br> 
Plasma levels of bradykinin are suppressed in factor XII-deficient mice. Iwaki T, Castellino FJ. Thromb Haemost. 2006 Jun;95(6):1003-10.<br> 
Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis. Kleinschnitz C, Stoll G, Bendszus M, Schuh K, Pauer HU, Burfeind P, Renné C, Gailani D, Nieswandt B, Renné T. J Exp Med. 2006 Mar 20;203(3):513-8. Epub 2006 Mar 13.
0.05 ml3400mol-innov2021
MFXIIKT-TOTFactor XII (aka Hageman Factor) is a single-chain, 615 amino acid glycoprotein zymogen. Factor XII is activated by kallikrein. Factor XIIa converts prekallikrein to kallikrein during the intrinsic pathway of the coagulation cascade. Although Factor XII is not thought to play an essential role in normal hemostasis, lack of Factor XII in a mouse model resulted in a severe defect in thrombus formation. The sensitive quantitative measurement of total mouse Factor XII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor XII and XIIa will be detected by the assay.</b> The concentration of Factor XII in normal human plasma ranges from 15-47 ug/ml. Normal values of Factor XII in mouse plasma have not been conclusively determined but are believed to be similar to human plasma based on in-house testing. The assay measures total mouse Factor XII in the 0.01-10 ng/ml range. Samples giving mouse Factor XII levels above 10 ng/ml should be diluted in blocking buffer before use. A 1:50,000 to 1:400,000 dilution for plasma is suggested for best results. Mouse Factor XII will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse Factor XII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor XII in the samples. A standard calibration curve is prepared using dilutions of purified Factor XII and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
MFXKT-TOTFactor X is a disulfide linked two-chain glycoprotein zymogen and is the precursor of the coagulation enzyme Factor Xa. Factor X is activated by Factor IXa in complex with Factor VIII, calcium and phospholipids during the intrinsic pathway and by Factor VIIa in complex with Tissue Factor, calcium and phospholipids during the extrinsic pathway of the coagulation cascade. The sensitive quantitative measurement of total mouse Factor X antigen in citrated plasma, serum, cell culture media, or tissue extract samples is easily performed with this 96 well strip format ELISA kit. <b>Factor X, Xa, and Xa in complex with inhibitors or cofactors will be detected by the assay.</b> The concentration of Factor X in normal plasma is 10 ug/ml. The assay measures total mouse Factor X in the 2.5-1000 ng/ml range. Samples giving mouse Factor X levels above 1000 ng/ml should be diluted in blocking buffer before use. A 1:100 dilution for plasma is suggested for best results. Mouse Factor X will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse Factor X primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of Factor X in the samples. A standard calibration curve is prepared using dilutions of purified Factor X and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
MIL17AKTMouse Interleukin-17A (aka IL-17, IL-17A or CTLA-8) is a 133 amino acid disulfide-linked homodimeric glycoprotein that is the founding member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that participates in neutrophil recruitment and is primarily expressed in CD4+ T cells. IL-17A has been shown in a mouse knockout model to play a vital role in allergen-specific immune responses via T cell activation. The sensitive quantitative measurement of total mouse IL-17A antigen in cell culture media samples is easily performed with this 96 well strip format ELISA kit. The assay measures total mouse IL-17A in the 0.01-10 ng/ml range. Samples giving mouse IL-17A levels above 10 ng/ml should be diluted in culture media or blocking buffer before use. Mouse IL-17A will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated anti-mouse IL-17A primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of IL-17A in the samples. A standard calibration curve is prepared using dilutions of purified IL-17A and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><br>1 kit5270mol-innov2021
MIL2-FCInterleukin-2 (IL-2) is a O-glycosylated
four alpha-helix bundle cytokine that is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells and is required for T-cell proliferation and other activities crucial to regulation of the immune response. Mouse IL-2 (Ala21-Gln169) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T-cells. (Gearing and Bird (1987) Production and assay of interleukin 2. In Lymphokines and Interferons: A Practical Approach (Clemens et al. eds.) pp. 291-301). The ED50 for this effect is typically < 1.0 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.<br>
<img src=/img/mouse-il-2.jpg><br>
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
 
0.05 mg2210mol-innov2021
MIL2-FC-CFInterleukin-2 (IL-2) is a O-glycosylated 
four alpha-helix bundle cytokine that is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells and is required for T-cell proliferation and other activities crucial to regulation of the immune response. Mouse IL-2 (Ala21-Gln169) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T-cells. (Gearing and Bird (1987) Production and assay of interleukin 2. In Lymphokines and Interferons: A Practical Approach (Clemens et al. eds.) pp. 291-301). The ED50 for this effect is typically < 1.0 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
<img src=/img/mouse-il-2.jpg><br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
0.05 mg5865mol-innov2021
MIL2KTMouse IL-2 (aka TCGF) is a 149 amino acid 15 kDa disulfide-linked monomeric glycosylate Type I cytokine [1]. IL-2 induces proliferation of a variety of lymphocytes including CD4+ and CD8+ T cells, natural killer cells, and B cells. Serum IL-2 levels are elevated in several cancers and autoimmune conditions and lymphocyte secretion is decreased in HIV patients. IL-2 binds to the IL-2R receptor which is composed of three subunits of varying affinity. The sensitive quantitative measurement of total mouse IL-2 antigen in plasma, serum, cell culture media, or other biological fluids samples is easily performed with this 96 well strip format ELISA kit. The assay measures total mouse IL-2 in the 0.01-10 ng/ml range. Samples giving mouse IL-2 levels above 10 ng/ml should be diluted in culture media or blocking buffer before use. Mouse IL-2 will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotinylated anti-mouse IL-2 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of IL-2 in the samples. A standard calibration curve is prepared using dilutions of purified IL-2 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5270mol-innov2021
MIRO-HISMiropin is a prokaryotic serpin (SErine Protease INhibitor) protein from Tannerella forsythia, a human pathogen involved in the pathogenesis of periodontitis. Miropin can inhibit the activity of a broad range of proteases including trypsin, cathepsin G, neutrophil and pancreatic elastases. Therefore, miropin is a unique serpin in its wide range of inhibitory activity. Recombinantly produced in insect cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at the N terminus for purification. This recombinant miropin inhibits the activity of human neutrophil elastase in vitro. At least 95percent pure as determined by SDS-PAGE.<br> 
References:<br> 
1. Ksiazek, M., Mizgalska, D., Enghild, J.J., Scavenius, C.,Thogersen, I.B., and Potempa, J. Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop. (2015) J. Biol. Chem. 290: 658-670.
0.01 mg3315mol-innov2021
MK-IGMPurified from normal rhesus monkey serum using size exclusion chromatography. >90% pure by SDS-PAGE. Major bands of ~70 and ~25 kDa indicative of the heavy and light chains of IgM on reducing SDS PAGE gels. IgG and IgA levels <2%.0.1 mg4930mol-innov2021
MKIGMKTImmunoglobulin M (IgM) is the first immunoglobulin produced in the immune response and is the third most abundant immunoglobulin in serum. IgM is a disulfide-linked 970kDa pentamer that activates complement and is responsible for red blood cell agglutination. Each monomer consists of two mu heavy chains and two kappa or lambda light chains. The sensitive quantitative measurement of total monkey IgM antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The concentration of IgM in normal monkey serum ranges from 0.8 to 1.9 mg/ml with an average concentration of 1.539 mg/ml. The assay measures monkey IgM in the 2.5-1,000 ng/ml range. Samples giving monkey IgM levels above 1,000 ng/ml should be diluted in blocking buffer before use. A 1:10,000 to 1:100,000 dilution for normal monkey serum or plasma is suggested for best results. Monkey IgM will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-monkey IgM primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of monkey IgM in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified monkey IgM and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6375mol-innov2021
MKNG-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving kininogen. Collected from homozygous kininogen knockout mice, anticoagulated with sodium citrate and flash frozen. Collected from male mice. Female mouse plasma is also available. Freshly collected kininogen knockout mouse organs are also available. The clotting time of this plasma is greatly extended compared to normal wild type plasma.0.05 ml3400mol-innov2021
MMIXTicTaqGo Detergent Free Multiplex Master Mix is a detergent-free formulation optimized for maximum amplification of two or more products simultaneously. It contains dNTPs, salts, stabilizers and high-quality TaqRobat recombinant native Taq DNA polymerase. Only primers, template and water need to be added. The 5X concentration allows maximum volume for the addition of DNA and multiple primers. It is ideal for automation due to its detergent-free formulation. Suitable for Standard Endpoint PCR and Genotyping of ten or more individual amplicons from GC-Rich DNA templates.100 rxn3995mol-innov2021
MPAIRecombinant mouse PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies. The active fraction typically contains 30-70percent active PAI-1.0.5 mg12155mol-innov2021
MPAI-BIOThis active fraction of recombinant wild type mouse PAI-1 is biotin labeled on lysine residues. Typical preparations are ~50 percent active.0.5 mg12155mol-innov2021
MPAI-I91LUsing information obtained from the studies which produced stabilized human PAI-1 (CPAI) we have available a form of mouse PAI-1 that has a single conservative mutation (Isoleucine 91 to Leucine).0.5 mg12155mol-innov2021
MPAI-KO-BRThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Brain1700mol-innov2021
MPAI-KO-HTThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Heart1700mol-innov2021
MPAI-KO-KDThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Kidney935mol-innov2021
MPAI-KO-LGThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. Each mouse lung consists of 5 lobes. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Lobe1700mol-innov2021
MPAI-KO-LRThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Liver1700mol-innov2021
MPAI-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving PAI-1. Collected from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. Anticoagulated with sodium citrate and flash frozen. Collected from male mice. Female mouse plasma is also available.<br>The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
0.05 ml935mol-innov2021
MPAI-KO-SPThis organ is an ideal negative control for western blotting, immunoprecipitation, immunohistochemistry and other experiments involving PAI-1. Collected and flash frozen from homozygous PAI-1 knockout mice of strain B6.129S2-Serpine1 tm1Mlg /J. The targeted PAI-1 knockout mutation was made on the C57BL/6J background strain. Mice homozygous for this mutation develop normally and are viable and fertile. Compared to wild type mice, pulmonary clot lysis is increased in the heterozygote and further increased in the homozygote. Endotoxin induced venous thrombosis is decreased compared to wild type mice. Thus, disruption of the Serpine1 gene induces a mild hyperfibrinolytic state. Hemostasis is normal in homozygous mutants.<br><br>
References:<br>
Carmeliet P; Kieckens L; Schoonjans L; Ream B; van Nuffelen A; Prendergast G; Cole M; Bronson R; Collen D; Mulligan RC. 1993. Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization. J Clin Invest 92(6):2746-55.
1 Spleen1700mol-innov2021
MPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active mouse PAI-1 in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration level of PAI-1 antigen in mouse plasma was found to be 1.9 ng/ml. The assay measures active PAI-1 in the 0.05-50 ng/ml range. Samples giving mouse PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. Normal plasma should be applied directly to the plate for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay. Cross-reactivity: 29percent rat PAI-1, 18percent rabbit PAI-1, 0.6percent porcine PAI-1, 76percent human PAI-1.</b> After appropriate washing steps, anti-mouse PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Negative control:  <a href=http://www.mol-innov。。com/item/Mouse-PAI-1-genetically-deficient-plasma-sodium-citrate>PAI-1 genetically deficient mouse plasma</a><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Urokinase-Coated-Plate>uPA Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 Kit8075mol-innov2021
MPAIKT-TOTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis.  The sensitive quantitative measurement of total mouse PAI-1 antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration level of PAI-1 antigen in mouse plasma was found to be 1.9 ng/ml. The assay measures mouse PAI-1 in the 0.05-50 ng/ml range. Samples giving mouse PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. Normal plasma should be applied directly to the plate for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Mouse PAI-1 will bind to the capture antibody coated on the microtiter plate. <b>Free, latent, and complexed PAI-1 will be detected by the assay. Cross-reactivity: 2percent porcine PAI-1, 1.7percent human PAI-1, 0.5percent rabbit PAI-1, 0.3percent rat PAI-1.</b> After appropriate washing steps, anti-mouse PAI-1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of mouse PAI-1 in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Negative control:  <a href=http://www.mol-innov。。com/item/Mouse-PAI-1-genetically-deficient-plasma-sodium-citrate>PAI-1 genetically deficient mouse plasma</a><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-PAI-1-Antigen-Capture-Plate>Mouse PAI-1 Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 Kit8075mol-innov2021
MPAI-LLatent mouse PAI-1 is a useful control for experiments when used in conjunction with the active form.0.5 mg12155mol-innov2021
MPAI-L-BIOThis latent fraction of recombinant mouse PAI-1 is biotin labeled on lysine residues. Biotin labeled latent mouse PAI-1 is a useful control for experiments involving active proteins.0.5 mg12155mol-innov2021
MPAI-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to mouse Plasminogen Activator Inhibitor (PAI-1) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of mouse PAI-1 antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
MPAI-TPAMouse sc-tPA is reacted with an excess of mouse PAI-1 stable mutant at physiological pH. The resulting 1:1 molar complex is purified from the remaining PAI-1 by affinity chromatography with immobilized antibodies to mouse tPA.0.1 mg6885mol-innov2021
MPC-HISThis high quality recombinant protein is an excellent replacement for plasma derived mouse Protein C which is no longer available. Incubation with thrombin generates Activated Protein C (APC) with activity on chromogenic substrate. Recombinantly produced in HEK cell culture and purified by a combination of chelated metal affinity and conventional chromatography. Contains a 8X-Histidine tag at C terminus for purification. The protein purity is determined by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Protein C is activated in vivo to the serine protease APC by alpha-thrombin or the complex of alpha-thrombin/thrombomodulin. APC is a potent anticoagulant through the selective inactivation of Factors Va and VIIIa.0.05 mg12070mol-innov2021
MPEChromatographically prepared from the euglobin fraction of pancreas by the method of Lewis et al. (1) then twice crystallized. The protein is stable 9-12 months when stored at 5 C and does not contain trypsin or chymotrypsin. 95percent pure by SDS-PAGE. Reconstitute with 0.05M Na Acetate 0.1M NaCl pH 5.0 to 1 mg/ml or desired concentration, aliquot and freeze remaining portion. Assay: 5-10 ug in 0.1M Tris pH 8.8 at 37 C containing 0.2mM Suc-(Al)3-pNA.<br>
References:<br> 1. Lewis, U.J. et al. (1956) J. Biol. Chem. 22:705
0.1 mg11560mol-innov2021
MPF4-RMouse PF-4 is expressed recombinantly and purified by chromatography. The purified protein in PBS is sterile filtered and lyophilized. Protein identity is confirmed by mass spectrometry (8.2 kDa monomer) and N-terminal sequencing (M-G-P-E-E). Purity is >95 percent by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.0.1 mg17680mol-innov2021
MPKRecombinant insect cell derived mouse prekallikrein is a single chain gamma globulin glycoprotein that participates in the early phase of contact activation, kinin formation and fibrinolysis. Prekallikrein is the zymogen precursor of the plasma serine protease kallikrein. Mouse Prekallikrein is >95percent pure by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. Specific activity is determined via complementation in an APTT clotting assay using prekallikrein immuno-deficient human plasma. Custom mutants of recombinant mouse prekallikrein are also available, please contact us for more details.0.1 mg8585mol-innov2021
MPK-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving prekallikrein, also known as plasma kallikrein B. Collected from homozygous prekallikrein knockout mice, anticoagulated with sodium citrate and flash frozen. Collected from male mice. Female mouse plasma is also available. Freshly collected prekallikrein knockout mouse organs are also available. The clotting time of this plasma is greatly extended compared to normal wild type plasma.0.05 ml3400mol-innov2021
MPKKT-TOTPrekallikrein is the glycosylated single chain zymogen precursor of the plasma serine protease kallikrein. Plasma prekallikrein circulates with kininogen and is activated by Factor XIIa in the intrinsic coagulation pathway. Kallikrein activates plasminogen in fibrinolysis and cleaves kininogen in the bradykinin system of vasodilation. Prekallikrein deficiency is rare and causes increased activated partial thromboplastin time. Elevated plasma prekallikrein is associated with diabetes and cardiovascular disease. The sensitive quantitative measurement of total mouse prekallikrein antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Kallikrein will be detected by the assay.</b> The concentration of prekallirein in normal human plasma is 15-55 ug/ml. Normal values of prekallikrein in mouse plasma have not been conclusively determined but are believed to be similar to human plasma based on in-house testing. The assay measures mouse prekallikrein in the 0.1-100 ng/ml range. Samples giving mouse prekallikrein levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:10,000-1:20,000 dilution for plasma is suggested for best results. Mouse prekallikrein will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse prekallikrein primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prekallikrein in the samples. A standard calibration curve is prepared using dilutions of purified prekallikrein and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
MPK-MABPACK20 ug of each of PK3A10, PK5G7, PK7G2, PK11H4, PK14E3, and PK13G5.1 pack8670mol-innov2021
MPLA-SCNormal US origin mouse plasma (Na Citrate). Control for PAI-1 depleted mouse plasma.10 ml2550mol-innov2021
MPLA-SC-PAIPrepared from frozen mouse plasma using immobilized anti-mouse PAI-1 IgG.10 ml8925mol-innov2021
MPLA-SER-GFPrepared from frozen US origin CD-1 mouse serum using immobilized Protein A.10 ml6970mol-innov2021
MPLA-SER-PGPrepared from frozen mouse serum.10 ml4420mol-innov2021
MPLGPrepared from fresh mouse plasma by immobilized lysine chromatography.1.0 mg6800mol-innov2021
MPLGKT-TOTPlasminogen is a single chain glycoprotein zymogen and is the precursor of the fibrinolytic enzyme plasmin. Plasminogen deficiencies are classified as hypoplasminogenemia (Type I) or dysplasminogenemia (Type 2) and are associated with decreased extracellular fibrin clearance leading to mucous membrane lesions and ligneous conjunctivitis. The sensitive quantitative measurement of total mouse plasminogen antigen in plasma, serum, or cell culture media  samples is easily performed with this 96 well strip format ELISA kit. <b>Plasminogen, plasmin and plasmin antiplasmin complex will be detected by the assay.</b> Plasminogen antigen was found to be 84 ug/ml in a small sample of normal mice. The assay measures total mouse plasminogen in the 2.5-500 ng/ml range. Samples giving mouse plasminogen levels above 500 ng/ml should be diluted in a similar fluid depleted of plasminogen or blocking buffer before use. A 1:1,000-1:10,000 dilution for plasma is suggested for best results. Mouse plasminogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-mouse plasminogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of plasminogen in the samples. A standard calibration curve is prepared using dilutions of purified plasminogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6120mol-innov2021
MPLMPrepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg8075mol-innov2021
MPN1Mouse Protease Nexin 1 (PN-1), recombinantly produced in insect cells. Active and fully complexable with tissue-type plasminogen activator. This SERPIN inhibits serine proteases such as thrombin, tPA and uPA, and is evolutionarily related to antithrombin and heparin cofactor II.0.1 mg9860mol-innov2021
MPOMyeloperoxidase purified from leucocytes of purulent human sputum which is >98percent pure. It is a lysosomal protein stored in azurophilic granules of the neutrophil which produces hypochlorous acid from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. Supplied as a lyophilized, salt-free, green soluble powder which is stable for over a year when stored at 5 C. 150-160 units per mg of protein. 1 unit will decompose 1 umole of H2O2 per minute at pH 7.0 and 25 C using 4-amino-antipyrine as hydrogen donor. Recommended assay buffer: 0.1 M KPO4; pH 7.01.0 mg10965mol-innov2021
MPREN-HISRecombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification. Resistant to activation to renin by trypsin digestion. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits a low level of enzymatic activity relative to renin which is generated from prorenin by proteolytic cleavage of the first ~43 amino acids at the N-terminus. This so called prosegment appears to block the full enzymatic potential of the active site (1). Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects(2).<br><br>

1) A.H. Jan Danser; Jaap Deinum ; Renin, Prorenin and the Putative (Pro)renin Receptor). Hypertension. 2005;46:1069.
<br><br>

2) Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M.
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular
complications. N Engl J Med. 1985;312:1412-1417.
0.1 mg5525mol-innov2021
MPRENKT-TOTProrenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects. Plasma and serum concentrations increase in several conditions such as pregnancy, progressive diabetes mellitus, diabetes mellitus with microvascular disease, and diabetic retinopathy. The sensitive quantitative measurement of total mouse prorenin and renin antigen in cell culture supernatant samples is easily performed with this 96 well strip format ELISA kit. <b>Renin and prorenin will be detected by the assay.</b> Mouse prorenin levels range from 20-30 ng/ml. The assay measures total mouse prorenin in the 0.2-100 ng/ml range. Mouse prorenin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse prorenin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with avidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prorenin in the samples. A standard calibration curve is prepared using dilutions of purified prorenin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8075mol-innov2021
MPRLProlactin (PRL, Mammotropin, Luterotropic hormone, Lutetropin) is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Expressed recombinantly and purified by chromatography. >95percent pure by SDS-PAGE and biologically active. Add deionized water to original volume, aliquot and freeze unused portion.0.05 mg4845mol-innov2021
MPRLKTProlactin (PRL) is a 199 aa, 23kD peptide hormone that is secreted primarily by the pituitary gland in both males and females, though its major roles are in pregnancy and lactation. Prolactin may have a role in breast cancer development, with higher prolactin levels correlating with postmenopausal breast cancer risk. The sensitive quantitative measurement of total mouse prolactin antigen in plasma is easily performed with this 96 well strip format ELISA kit. The concentration of prolactin in pooled normal mouse plasma determined by in house testing was 4.7 ng/ml. Prolactin levels are elevated in pregnant mice and peak at day 8 of pregnancy. The assay measures total mouse prolactin in the 0.1-100 ng/ml range. Samples with mouse prolactin levels above 100 ng/ml should be diluted in blocking buffer before use. Normal plasma may be applied directly to the plate or diluted 1:1 with blocking buffer. Mouse prolactin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse prolactin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prolactin in the samples. A standard calibration curve is prepared using dilutions of purified prolactin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit7905mol-innov2021
MPRLR-FCProlactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain (Ser21-Asp229) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured by inhibitory activity toward prolactin-induced proliferation of Nb2-11 rat lymphoma cells (Gout et al. (1980) Cancer Res. 40:2433). ED50 for this effect is typically < 10 ng/ml in the presence of 0.5 ng/ml of recombinant human Prolactin. Add deionized water to original volume, aliquot and freeze unused portion.<br>
<img src=/img/prolactin-receptor.jpg><br>
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
0.1 mg5185mol-innov2021
MPTKTProthrombin is a single-chain vitamin K dependent 579 amino acid glycoprotein zymogen. Prothrombin levels are decreased by anticoagulant therapy, vitamin K deficiency and severe liver disease. Elevated plasma prothrombin is associated with a single nucleotide change at position 20210. The sensitive quantitative measurement of mouse prothrombin in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Thrombin and thrombin-antithrombin
complex will not be detected by the assay.</b> Prothrombin in normal human plasma ranges from 110-212 ug/ml with an average concentration of 150 ug/ml. Normal values of prothrombin in mouse plasma have not been conclusively determined but are believed to be similar to human plasma. The assay measures mouse prothrombin in the 1-500 ng/ml range. Samples giving mouse prothrombin levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:10,000 dilution for plasma is suggested for best results. Mouse prothrombin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse prothrombin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prothrombin in the samples. A standard calibration curve is prepared using dilutions of purified prothrombin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses a unique antibody to only detect prothrombin.</font> A total antigen kit that will detect prothrombin, thrombin and TAT complex is available under <a href=http://www.mol-innov。。com/index.php?page=products&item=MPTKT-TOT><font color=blue>catalog number MPTKT-TOT</font></a>.
<br><br>
1 kit6885mol-innov2021
MPTKT-TOTProthrombin is a single-chain vitamin K dependent 579 amino acid glycoprotein zymogen. Prothrombin levels are decreased by anticoagulant therapy, vitamin K deficiency and severe liver disease. Elevated plasma prothrombin is associated with a single nucleotide change at position 20210. The sensitive quantitative measurement of total mouse prothrombin antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Thrombin and thrombin-antithrombin complex will be detected by the assay.</b> Prothrombin in normal human plasma ranges from 110-212 ug/ml with an average concentration of 150 ug/ml. Normal values of prothrombin in mouse plasma have not been conclusively determined but are believed to be similar to human plasma. The assay measures mouse prothrombin in the 1-500 ng/ml range. Samples giving mouse prothrombin levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:10,000 dilution for plasma is suggested for best results. Mouse prothrombin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse prothrombin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prothrombin in the samples. A standard calibration curve is prepared using dilutions of purified prothrombin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
We also offer a kit that is specific for prothrombin and will not detect thrombin or TAT complex under <a href=http://www.mol-innov。。com/index.php?page=products&item=MPTKT-TOT><font color=blue>catalog number MPTKT</font></a>.<br><br>
1 kit5525mol-innov2021
MSAAlbumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. Prepared from US origin mouse plasma by proprietary fractionation methods and lyophilized. >95percent pure by SDS-PAGE. Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.<br><br>
<font color=red><b>SPECIAL PRICE BREAK: 1 gram for only $995!</b></font><br><br>
Now available: <a href=http://www.mol-innov。。com/item/Mouse-albumin-ELISA-Kit>Mouse Albumin ELISA Kit</a> for plasma, serum and urine<br>
100 mg3400mol-innov2021
MSAKTAlbumin is a water-soluble protein with considerable structural stability which makes up 60 percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. The sensitive quantitative measurement of total mouse albumin (murine serum albumin, MSA) in plasma, serum, urine or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. This kit has been validated for measurement of albumin in BALB/c mouse urine (33 ug/ml), nude mouse urine (19 ug/ml), and CD1 mouse plasma (29 mg/ml). Albumin is present in normal mouse plasma at a concentration of 20-30 mg/ml.  The assay measures mouse albumin in the 1-1000 ng/ml range. Samples giving mouse albumin levels above 1000ng/ml should be diluted in 1X diluent before use. A 1:500,000 to 1:1,000,000 dilution for normal plasma or a 1:1,000 dilution for urine is suggested for best results. Mouse albumin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-mouse albumin primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of mouse albumin in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse albumin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Also available: High quality <a href=http://www.mol-innov。。com/item/Albumin-Mouse-Plasma>mouse albumin</a> purified from US origin plasma<br>
1 kit6120mol-innov2021
MSBC-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg3060mol-innov2021
MSC57BL6-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg6885mol-innov2021
MSCD1-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg3060mol-innov2021
MS-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg1360mol-innov2021
MS-GF-EDPurified from normal serum by immobilized Protein A using low endotoxin methodology. The purified protein is sterile filtered and lyophilized from azide fee PBS. >95percent pure by SDS-PAGE and <1 EU/mg.50 mg6885mol-innov2021
MSIGAKTImmunoglobulin A (IgA) is the main immunoglobulin in mucous secretions and the second most abundant immunoglobulin in serum. It defends against inhaled and ingested pathogens by binding an Fc receptor on myeloid leukocytes. The equivalent mouse receptor has not yet been identified. Human IgA has two distinct subclasses and is monomeric in serum while mouse IgA does not have subclasses and is dimeric in serum. The sensitive quantitative measurement of total mouse IgA antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit.<b>The kit does not cross react significantly with rat, pig, sheep, dog, rabbit, cyno monkey, rhesus monkey, or human IgA.</b> The concentration of IgA was found to be 0.4 mg/ml in NIH Swiss mouse serum and 0.7 mg/ml in BALB/C mouse serum. The assay measures mouse IgA in the 0.1-100 ng/ml range. Samples giving mouse IgA levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:200,000 dilution for serum is suggested for best results. Mouse IgA will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-mouse IgA primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of mouse IgA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse IgA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6035mol-innov2021
MS-IGG1This Mouse IgG1 isotype control antibody (Anti-KLH) has been tested against selected species' cells and tissues to assure minimal cross reactivity. Purified by immobilized Protein A/G. IgG1 kappa class. &gt;95 percent pure by SDS-PAGE and preservative free.1.0 mg5270mol-innov2021
MS-IGG2AThis Mouse IgG2a isotype control antibody (Anti-KLH) has been tested against selected species' cells and tissues to assure minimal cross reactivity. Purified by immobilized Protein A/G. IgG2a kappa class. &gt;95 percent pure by SDS-PAGE and preservative free.1.0 mg5270mol-innov2021
MS-IGG2BThis Mouse IgG2b isotype control antibody (Anti-KLH) has been tested against selected species' cells and tissues to assure minimal cross reactivity. Purified by immobilized Protein A/G. IgG2b kappa class. &gt;95 percent pure by SDS-PAGE and preservative free.1.0 mg5270mol-innov2021
MS-IGG3This Mouse IgG3 isotype control antibody (Anti-KLH) has been tested against selected species' cells and tissues to assure minimal cross reactivity. Purified by immobilized Protein A/G. IgG3 kappa class. &gt;95 percent pure by SDS-PAGE and preservative free.1.0 mg5270mol-innov2021
MSIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total mouse IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react significantly with rat, human, guinea pig, or rabbit IgG.</b> The concentration of IgG in normal mouse serum ranges from 5 to 12 mg/ml. The assay measures mouse IgG in the 0.1-100 ng/ml range. Samples giving mouse IgG levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000 to 1:20,000,000 dilution for serum is suggested for best results. Mouse IgG will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-mouse IgG primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of mouse IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit3995mol-innov2021
MS-IGMThis Mouse IgM isotype control antibody is purified from normal mouse serum by affinity chromatography. &gt;95 percent pure by SDS-PAGE and preservative free.1.0 mg2975mol-innov2021
MSIGMKTImmunoglobulin M (IgM) is the first immunoglobulin produced in the immune response and is the third most abundant immunoglobulin in serum. IgM is a disulfide-linked 970kDa pentamer that activates complement and is responsible for red blood cell agglutination. Each monomer consists of two mu heavy chains and two kappa or lambda light chains. The sensitive quantitative measurement of total mouse IgM antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The concentration of IgM in normal mouse serum ranges from 0.5 to 2.0 mg/ml. The assay measures mouse IgM in the 0.5-500 ng/ml range. Samples giving mouse IgM levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:5,000 to 1:10,000 dilution for normal mouse serum or plasma is suggested for best results. Mouse IgM will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-mouse IgM primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of mouse IgM in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse IgM and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6120mol-innov2021
MS-TL-CBA freshly-harvested Balb C mouse brain is dissected and the cerebellum is flash-frozen in liquid nitrogen and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
MS-TL-CCA freshly-harvested Balb C mouse brain is dissected and the cerebral cortex is flash-frozen in liquid nitrogen and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
MS-TL-KDA freshly-harvested Balb C mouse kidney is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
MTHROMMouse thrombin is prepared from purified mouse prothrombin by activation with coastal taipan venom followed by affinity chromatography. Purity is verified by SDS-PAGE analysis and specific activity in NIH thrombin units is determined by chromogenic substrate.0.05 mg4590mol-innov2021
MTPARecombinantly produced in insect cells. >95percent active.0.1 mg5695mol-innov2021
MTPA-ALANCMouse tPA with a double mutation that is permanently single chain and lacks catalytic activity. The non-catalytic mutation site is S481A on the mature protein and S510A on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). The non-cleavable mutation site is 279E on the mature protein and R308E on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). Recombinantly produced in insect cells.0.1 mg5695mol-innov2021
MTPA-BIORecombinantly produced in insect cells and biotin labeled.0.05 mg5695mol-innov2021
MTPA-FITCRecombinantly produced in insect cells and fluorescein labeled.0.05 mg5695mol-innov2021
MTPA-KO-SCThis plasma is an ideal negative control for ELISA based assays and other experiments involving Tissue Plasminogen Activator (tPA). Collected from homozygous tPA knockout mice, anticoagulated with sodium citrate and flash frozen. Pooled from male and female mice. Freshly collected tPA knockout mouse organs are also available.0.05 ml3400mol-innov2021
MTPAKTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of functionally active mouse tPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The level of active tPA in normal plasma was found to be 9.9 ng/ml in NSA/CF-1, 1.4 ng/ml in C57BL6, and 0.4 ng/ml in CD-1 mouse strains. The assay measures active tPA in the 0.05-50 ng/ml range. Samples giving mouse tPA levels above 50 ng/ml should be diluted in blocking buffer before use. Samples of plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active tPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the 10X TBS provided in the kit. Serum and cell culture media at neutral pH may also be used. Functionally active tPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Complexed tPA will not bind to the PAI-1 and will not be detected by the assay.</b> After appropriate washing steps, anti-mouse tPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active tPA in the samples. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
MTPAKT-TOTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of total mouse tPA antigen in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The level of tPA antigen in normal plasma was found to be 9.4 ng/ml in NSA/CF-1, 2.4 ng/ml in C57BL6, and 0.4 ng/ml in CD-1 mouse strains. The assay measures total tPA in the 0.1-50 ng/ml range. Samples giving mouse tPA levels above 50 ng/ml should be diluted in blocking buffer before use. Mouse tPA will bind to the capture antibody coated on the microtiter plate. <b>Free and complexed tPA will be detected by the assay.</b> After appropriate washing steps, anti-mouse tPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of mouse tPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-tPA-Antigen-Capture-Plate>tPA Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
MTPA-NCThe addition of an arginine to glutamic acid mutation generates mouse tPA that is 100percent single chain and resistant to cleavage by plasmin. The mutation site is R279E on the mature protein and R308E on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). Recombinantly produced in insect cells.0.1 mg5695mol-innov2021
MTPA-S481AThis single chain mouse tPA has the active site serine mutated to alanine rendering the enzyme catalytically inactive. The mutation site is S481A on the mature protein and S510A on the complete mRNA sequence (UniProtKB: locus TPA_MOUSE, accession P11214). The tPA still retains exosite binding as well as other biological properties of tPA including but not limited to surface binding to fibrin. This protein is not sterile and should be passed through a 0.22 micron filter before use in cell culture.0.1 mg5695mol-innov2021
MTPA-TCRecombinantly produced in insect cells. Activated from single-chain form with immobilized plasmin. >95percent two chain, >95percent active.0.1 mg7480mol-innov2021
MTPA-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to mouse Tissue-type Plasminogen Activator (tPA) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of mouse tPA antigen for sandwich style ELISA experiments. Cross reacts with rat tPA.1 plate2210mol-innov2021
MTPO-FCThrombopoietin (TPO), also known as Thrombopoiesis Stimulating Factor (TSF), is a glycoprotein hormone and the major stimulator of megakaryopoiesis and platelet production. TPO is expressed in liver, kidney, spleen, lung, bone marrow, and brain. The TPO receptor is a product of the proto-oncogene c-mpl and displays homology with type I cytokine receptor superfamily members. The receptor is present mainly on hematopoietic stem cells, megakaryocytic progenitors, megakaryocytes, and platelets. TPO is the primary regulator of platelet production by megakaryocytes. It stimulates the proliferation of hematopoietic stem cells, primitive progenitors, megakaryocytes, and platelets. Analogous to the effect of erythropoietin (EPO), the primary mode of action of TPO is inhibition of apoptosis of its target cells. By contrast, TPO is strongly proapoptotic in the brain and acts as a counterpart of EPO which has neuroprotective properties.<br> 
Mouse TPO (Ser22-Thr356) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. Mouse TPO can be used for a variety of applications, including megakaryocyte proliferation and differentiation in vitro, in vitro expansion of hematopoietic stem cells, in vitro platelet activation and apoptosis assays. >95percent pure by SDS-PAGE and biologically active as measured in a proliferation assay with human TF-1 erythroleukemia cells (Drexler et al. (1997) Leukemia 11:541-551). The ED50 for this activity is typically < 5 ng/ml. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
<img src=/oldsite/img/mouse-tpo.jpg><br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. This protein appears in multiple glycoforms in SDS-PAGE under both non-reducing and reducing conditions.
0.1 mg5185mol-innov2021
MUPAActive two-chain HMW mouse urokinase, recombinantly produced in insect cells.0.05 mg5015mol-innov2021
MUPA-AF700Active two-chain HMW mouse urokinase, recombinantly produced in insect cells. Labeled with Alexa Fluor 700 at primary amines (Abs: 702, Em: 723).0.05 mg8670mol-innov2021
MUPA-BIOBiotin labeled Mouse Urokinase.0.05 mg8670mol-innov2021
MUPA-FITCFluorescein labeled Mouse Urokinase.0.05 mg8670mol-innov2021
MUPA-INInactivated two-chain HMW mouse urokinase, recombinantly produced in insect cells. Prepared from active mouse uPA by active site-specific inactivation with Phe-Pro-Arg chloromethyl ketone followed by removal of excess inhibitor by extensive dialysis.0.05 mg8670mol-innov2021
MUPAKTUrokinase plasminogen activator (uPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion/migration. The sensitive quantitative measurement of functionally active mouse uPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The concentration level of uPA antigen in mouse urine has been reported to be 1.8 ug/ml. The assay measures active uPA in the 0.025-10 ng/ml range. Samples giving mouse uPA levels above 10 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active uPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the 10X TBS provided in the kit. Serum and cell culture media at neutral pH may also be used. If using kidney extracts that have been extracted using triton X, dialyze to remove the triton X before using in the assay. Detergents such as triton X may interfere with the assay. Functionally active uPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Inactive or complexed uPA will not bind to the PAI-1 and will not be detected by the assay. Cross-reactivity: 1percent Human uPA.</b> After appropriate washing steps, anti-mouse uPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active uPA in the samples. A standard calibration curve is prepared using dilutions of purified uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
MUPAKT-TOTUrokinase plasminogen activator (uPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion/migration. The sensitive quantitative measurement of total mouse uPA antigen in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The concentration level of uPA antigen in mouse urine has been reported to be 1.8 ug/ml. The assay measures total uPA in the 0.01-10 ng/ml range. Samples giving mouse uPA levels above 10 ng/ml should be diluted in blocking buffer before use. Mouse uPA will bind to the capture antibody coated on the microtiter plate. <b>Free and complexed uPA will be detected by the assay. This kit does not cross react with human uPA.</b> After appropriate washing steps, anti-mouse uPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of mouse uPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-uPA-Antigen-Capture-Plate>uPA Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
MUPA-LMWLow molecular weight active mouse urokinase, recombinantly produced in insect cells.0.05 mg9010mol-innov2021
MUPA-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to mouse Urokinase Plasminogen Activator (uPA) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of mouse uPA antigen for sandwich style ELISA experiments. Cross reacts with rat uPA.1 plate2210mol-innov2021
MVNPrepared from fresh mouse plasma using urea as a denaturant.0.1 mg4590mol-innov2021
MVNKT-TOTVitronectin is an abundant plasma glycoprotein that helps regulate coagulation, fibrinolysis, complement activation, and cell adhesion. Vitronectin binds to glycosaminoglycans, collagen, plasminogen and urokinase receptors. It also may control the clearance of vascular thrombi by binding and stablilizing PAI-1. In binding PAI-1, it extends the lifetime of active PAI-1. Vitronectin may also be involved in the regulation of bone metabolism. The sensitive quantitative measurement of total mouse vitronectin antigen in plasma, serum, culture media or tissue extract samples is easily performed with this 96 well strip format ELISA kit. The vitronectin concentration in mouse serum has been estimated at 300 ug/ml by semi-quantitative immunoblotting. The assay measures total vitronectin in the 0.1-100 ng/ml range.  Samples giving mouse vitronectin levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:10,00 to 1:40,000 dilution for mouse plasma or serum is suggested for best results. Mouse vitronectin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-mouse vitronectin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of mouse vitronectin in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified mouse vitronectin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-Vitronectin-Antigen-Capture-Plate>Mouse Vitronectin Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Avidin-HRP-Labeled>Avidin-HRP</a>
1 Kit8075mol-innov2021
MVN-TOT-PLATE96 well plate with 8 removable strips coated with affinity purified polyclonal antibody to mouse Vitronectin at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of mouse vitronectin antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
MZPIMouse Protein Z-Dependent Protease Inhibitor (ZPI), recombinantly produced in insect cells. Active and complexable with Factor XIa. This Serine Protease Inhibitor (SERPIN) requires the cofactors Protein Z, phospholipids and calcium to inhibit endogenous Factor Xa. ZPI contains a tyrosine residue at the P1 position of the reactive center loop, rather than arginine which is present in most SERPINs.<br>
References<br>
1. Han, X. et al. (1998) PNAS 95:9250?9255.<br>
2. Huang, X. et al. (2008) J. Biol. Chem. 283:29770?29783.
0.1 mg9860mol-innov2021
NTAF488CPAIStable mutant human PAI-1 labeled with Alexa Fluor 488 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAF488PAI-AActive human PAI-1 labeled with Alexa Fluor 488 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAF488PAI-LLatent human PAI-1 labeled with Alexa Fluor 488 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAF594CPAIStable mutant human PAI-1 labeled with Alexa Fluor 594 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAF594PAI-AActive human PAI-1 labeled with Alexa Fluor 594 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAF594PAI-LLatent human PAI-1 labeled with Alexa Fluor 594 by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg16575mol-innov2021
NTAQTaqRobat Native Taq DNA Polymerase is a recombinant Taq that has identical characteristics to native Taq from Thermus aquaticus. This highly robust enzyme consists of a single polypeptide with a molecular weight of approximately 94 kDa, and will create products with dA overhangs at 3' ends. Suitable for Standard Endpoint PCR, Colony PCR, Genotyping, and TA Cloning of DNA templates up to 5kb. TaqRobat offers higher yields than some leading competitors with excellent lot-to-lot reproducibility. TaqRobat undergoes extensive quality control and is free of contaminating endonucleases.<br><br> 
Supplied with your choice of complimentary MgCl2 or MgCl2 free 10X PCR reaction buffer.<br><br> 
<b>Thermal cycling conditions:</b> The following general cycling conditions are recommended but can vary depending on the template and primers being used.<br> 
<table border=1px padding=5px> 
<tr><th>Cycling Step</th><th>Temperature</th><th>Holding Time</th><th>Cycles</th></tr> 
<tr><td>Initial Denaturation</td><td>94&deg;C</td><td>2min</td><td>1</td></tr> 
<tr><td>Denaturation</td><td>94-96&deg;C</td><td>30sec-4min</td><td rowspan=3>20-30</td></tr> 
<tr><td>Annealing*</td><td>55-65&deg;C</td><td>15-30sec</td></tr> 
<tr><td>Extension</td><td>70-72&deg;C</td><td>30sec-1min per kb</td></tr> 
<tr><td>Final Extension</td><td>70-72&deg;C</td><td>0-10min</td><td>1</td></tr> 
</table> 
*Annealing temperature will depend on primer length and composition. Generally, begin 5&deg;C below primer Tm.
500 units2040mol-innov2021
NTAQGREENTaqRobat Native Taq MantisGreen 2X Master Mix is an optimized, ready-to-use mix that contains dNTPs, buffers, stabilizers, MantisGreen loading dyes and our TaqRobat recombinant Taq DNA polymerase. Reactions can go directly from PCR tube to gel. The mix is a 2X formulation that requires only the addition of primers, template and water. MantisGreen dual-color loading dyes do not inhibit PCR and make monitoring progress easy during electrophoresis. The dyes run outside the range of typical PCR products and therefore do not obscure visualization. The blue dye runs at 4kb and the yellow dye runs under 25bp. TaqRobat 2X Master Mix provides robust amplification over a wide range of templates up to 5kb. Suitable for direct-to-gel Standard Endpoint PCR, Colony PCR, Low Copy PCR, Genotyping, and TA Cloning. Also available without loading dyes.<br><br><b>Reaction setup:</b> The following setup is recommended for a 50&micro;l reaction but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Component</th><th>Volume</th><th>Final Concentration</th></tr> <tr><td>Master Mix</td><td>25&micro;l</td><td>1X</td></tr> <tr><td>5' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td></tr> <tr><td>3' Primer, 10&micro;M</td><td>0.5-5&micro;l</td><td>0.1-1&micro;M</td> <tr><td>DNA Template</td><td>0.1-5&micro;l</td><td>&gt;1ng</td></tr> <tr><td>Nuclease Free Water</td><td colspan=2>QS to 50&micro;l</td></tr></table> 
<br><br><b>Thermal cycling conditions:</b> The following general cycling conditions are recommended but can vary depending on the template and primers being used.<br> <table border=1px padding=5px> <tr><th>Cycling Step</th><th>Temperature</th><th>Holding Time</th><th>Cycles</th></tr> <tr><td>Initial Denaturation</td><td>94&deg;C</td><td>30sec-2min</td><td>1</td></tr> <tr><td>Denaturation</td><td>94-96&deg;C</td><td>15-30sec</td><td rowspan=3>20-30</td></tr> <tr><td>Annealing*</td><td>55-65&deg;C</td><td>15-60sec</td></tr> <tr><td>Extension</td><td>70-72&deg;C</td><td>1min per kb</td></tr> <tr><td>Final Extension</td><td>70-72&deg;C</td><td>0-10min</td><td>1</td></tr> </table> *Annealing temperature will depend on primer length and composition. Generally, begin 5&deg;C below primer Tm.
500 rxn3825mol-innov2021
NTAQMIXTaqRobat Native Taq 2X Master Mix is an optimized, ready-to-use mix that contains dNTPs, buffers, stabilizers and our TaqRobat recombinant Taq DNA polymerase. It is supplied in a 2X formulation that requires only the addition of primers, template and water. TaqRobat 2X Master Mix provides robust amplification over a wide range of templates up to 5kb. Suitable for Standard Endpoint PCR, Colony PCR, Low Copy PCR, Genotyping, and TA Cloning. Also available containing MantisGreen dual-color loading dyes.500 rxn3825mol-innov2021
NTBIOCPAIStable mutant human PAI-1 biotin labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
NTBIOMPAI-I91LMouse PAI-1 stable mutant biotin labeled by iodoacetamide substitution at the N-terminal cysteine. This mouse PAI-1 has a single conservative mutation (Isoleucine 91 to Leucine) that conveys extended stability and half life at pH 7.4.0.5 mg15640mol-innov2021
NTBIOPAI-AActive human PAI-1 biotin labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
NTBIOPAI-LLatent human PAI-1 biotin labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
NTCYSCPAIThis stable form of PAI-1 contains an N-terminal cysteine mutation in addition to the four stabilization mutations (patent pending). The protein is supplied in buffer with 1mM DTT to prevent dimerization. To label with thiol reactive dye, buffer exchange into degassed 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 by desalting column. Collect into 10 fold molar excess of maleimide or iodoacetamide dye and incubate for 1 hour at room temperature. To preserve PAI-1 activity minimize the percentage of DMSO/DMF in the reaction. Remove free dye by desalting, ammonium sulfate precipitation, or dialysis.0.5 mg12155mol-innov2021
NTCYSCPAI-R76EThis stable form of PAI-1 contains an N-terminal cysteine mutation in addition to the four stabilization point mutations. A substitution of Glutamic Acid for Arginine at position 76 greatly decreases the binding of this Human PAI-1 mutant to the low density lipoprotein receptor-related protein (LRP). The protein is supplied in buffer with 1mM DTT to prevent dimerization. To label with thiol reactive dye, buffer exchange into degassed 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 by desalting column. Collect into 10 fold molar excess of maleimide or iodoacetamide dye and incubate for 1 hour at room temperature. To preserve PAI-1 activity minimize the percentage of DMSO/DMF in the reaction. Remove free dye by desalting, ammonium sulfate precipitation, or dialysis.0.5 mg12155mol-innov2021
NTCYSCPAI-T333RThis stable form of PAI-1 contains an N-terminal cysteine mutation in addition to the four stabilization point mutations. A single substitution at position P14 in the reactive center loop produces a PAI-1 that becomes a substrate for proteinases rather than an inhibitor. The protein is supplied in buffer with 1mM DTT to prevent dimerization. To label with thiol reactive dye, buffer exchange into degassed 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 by desalting column. Collect into 10 fold molar excess of maleimide or iodoacetamide dye and incubate for 1 hour at room temperature. To preserve PAI-1 activity minimize the percentage of DMSO/DMF in the reaction. Remove free dye by desalting, ammonium sulfate precipitation, or dialysis.0.5 mg12155mol-innov2021
NTCYSPAI-AWild type PAI-1 cloned with a cysteine residue at the N-terminus (patent pending). The active fraction is >95percent pure and >95percent active as determined by titration with HWM tc-urokinase and SDS PAGE. The protein is supplied in buffer with 1 mM DTT to prevent dimerization. To label with thiol reactive dye, buffer exchange into degassed 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 by desalting column. Collect into 10 fold molar excess of maleimide or iodoacetamide dye and incubate for 1 hour at room temperature. To preserve PAI-1 activity minimize the percentage of DMSO/DMF in the reaction. Remove free dye by desalting, ammonium sulfate precipitation, or dialysis.0.5 mg12155mol-innov2021
NTCYSPAI-LWild type PAI-1 cloned with a cysteine residue at the N-terminus (patent pending). The latent fraction is <0.4percent active as determined by titration with HMW tc-urokinase and SDS PAGE. The protein is supplied in buffer with 1 mM DTT to prevent dimerization. To label with thiol reactive dye, buffer exchange into degassed 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 by desalting column. Collect into 10 fold molar excess of maleimide or iodoacetamide dye and incubate for 1 hour at room temperature. Remove free dye by desalting, ammonium sulfate precipitation, or dialysis.0.5 mg12155mol-innov2021
NTFLCPAIStable mutant human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
NTFLPAI-AActive human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
NTFLPAI-LLatent human PAI-1 fluorescein labeled by iodoacetamide substitution at the N-terminal cysteine (patent pending).0.5 mg12155mol-innov2021
PAI3A120Non-inhibitory monoclonal antibody to human PAI-1. Strongly reactive with human PAI-1 free and complexed with tPA. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg7990mol-innov2021
PAI3C311Non-inhibitory monoclonal antibody to human PAI-1. Produces excellent western blots with both free and complexed forms of PAI-1. Strongly reactive with human, rat, rabbit, and porcine PAI-1. IgG fraction purified by immobilized Protein A. Isotype IgG.1.0 mg7990mol-innov2021
PAI3E529Non-inhibitory monoclonal antibody to human PAI-1. Recommended for detection of human PAI-1 in ELISA. Purified by immobilized Protein A/G. IgG1k class.1.0 mg7990mol-innov2021
PAI-AHuman wild type PAI-1 is produced as an active and latent form in E. Coli. The purification conditions are gentle and result in an active fraction >99percent pure and >98percent active as determined by titration with HMW tc-urokinase and SDS PAGE.0.5 mg12155mol-innov2021
PAI-A-ANActive human wild-type (wt) PAI-1 is also available pre-annealed with the Octapeptide Ac-TVASSSTA and ready for immediate use. Please inquire regarding other species of annealed PAI-1.0.5 mg12155mol-innov2021
PAI-CHuman PAI-1 is provided cleaved at P3-P4 residues via immobilized elastase: <1percent active. Useful for various control experiments requiring a non-reactive, reactive loop inserted species of PAI-1.0.5 mg12155mol-innov2021
PAI-L<0.4percent active as determined by titration with HMW tc-urokinase and SDS PAGE. Latent PAI-1 is a useful control for experiments when used in conjunction with the active from.0.5 mg12155mol-innov2021
PATIIIPrepared from fresh porcine (pig) plasma using several chromatographic steps.1.0 mg7735mol-innov2021
PEP-1Ac-TVASSSTA is an Octapeptide mimic of the N-terminal residues of the reactive center loop of PAI-1 (cf. P14-P7 residues). The Octapeptide inactivates PAI-1 by substituting for strand 4 in beta-sheet A in a manner that competes with formation of the latent species. Insertion of the peptide into beta-sheet A effectively forms a stable complex that converts PAI-1 into a substrate for tissue-type plasminogen activator (tPA) and other target proteinases. The resulting species of PAI-1 is thermodynamically stable and is useful for investigating the role of reactive center loop insertion. Supplied as a lyophilized powder. Add deionized water to original volume, aliquot and freeze unused portion.5.0 mg8500mol-innov2021
PFBGNPrepared from fresh porcine plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.25 mg4420mol-innov2021
PFBGN-FITCPorcine fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh porcine plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.10 mg4420mol-innov2021
PFBGNKTFibrinogen is a soluble glycoprotein that circulates in the blood and is converted to insoluble fibrin by thrombin in the final step of the coagulation cascade. Hepatic expression of fibrinogen increases two to four hundred fold during the acute phase response to infection or inflammation. Elevated fibrinogen levels are correlated with cardiovascular disease and atherosclerosis. The sensitive quantitative measurement of porcine fibrinogen (pig fibrinogen) in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. Fibrinogen is present in normal porcine plasma at a concentration of 2-4 mg/ml. The assay measures total porcine fibrinogen in the 1.56-800 ng/ml range. Samples giving porcine fibrinogen levels above 800 ng/ml should be diluted in 1X diluent before use. A 1:500,000 to 1:1,000,000 dilution for plasma or serum is suggested for best results. Porcine fibrinogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-porcine fibrinogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of fibrinogen in the samples. A standard calibration curve is prepared using dilutions of purified fibrinogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5185mol-innov2021
PFIIPorcine prothrombin is prepared from pig plasma by a proprietary combination of precipitations and conventional chromatography. Porcine prothrombin (Factor II) is a glycoprotein of molecular weight 72,000, and consists of a single polypeptide chain. Activation of prothrombin by Factor Va, Xa and phospholipids yields the serine protease thrombin. Prothrombin purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol.1.0 mg4250mol-innov2021
PK10G3Mouse monoclonal antibody to human prekallikrein. Excellent reagent for <b>affinity purification</b> of prekallikrein from human plasma. IgG fraction purified by immobilized Protein G. Clone 10G3-42, isotype IgG1 kappa. Also available <a href=http://www.mol-innov。。com/item/Immobilized-monoclonal-antibody-to-human-prekallikrein-and-kallikrein>immobilized to agarose resin</a>.0.1 mg8670mol-innov2021
PK10G3-IImmobilized monoclonal antibody to human prekallikrein and kallikrein. This immobilized antibody is extremely useful for the affinity purification of prekallikrein and kallikrein from chromatography fractions or directly from human plasma.1.0 ml2210mol-innov2021
PK11H4Mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a capture antibody in ELISA assays. Clone 11H4-F10F10, isotype IgG2b Kappa. Does not compete with PK3A10, PK5G7, PK7G2, PK13G5, or PK14E3 as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK11H4-BIOBiotin labeled mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 11H4-F10F10, isotype IgG2b Kappa. Does not compete with PK3A10, PK5G7, PK7G2, PK13G5, or PK14E3 as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PK13G5Inhibitory mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. Extends the clotting time of normal mouse plasma. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a capture antibody in ELISA assays. Clone 13G5-E8D10, isotype IgG1 Kappa. Does not compete with PK3A10, PK5G7, PK7G2, PK11H4, or PK14E3 as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK13G5-BIOBiotin labeled inhibitory mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. Extends the clotting time of normal mouse plasma. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 13G5-E8D10, isotype IgG1 Kappa. Does not compete with PK3A10, PK5G7, PK7G2, PK11H4, or PK14E3 as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PK14E3Inhibitory mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. Extends the clotting time of normal mouse plasma. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a capture antibody in ELISA assays. Clone 14E3-D6E8, isotype IgG1 Kappa. Shares a partial epitope with PK11H4 as determined by competitive ELISA. Does not compete with PK3A10, PK5G7, PK7G2, or PK11H4. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK14E3-BIOBiotin labeled inhibitory mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. Extends the clotting time of normal mouse plasma. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 14E3-D6E8, isotype IgG1 Kappa. Shares a partial epitope with PK11H4 as determined by competitive ELISA. Does not compete with PK3A10, PK5G7, PK7G2, or PK11H4. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PK20E7Mouse monoclonal antibody to human prekallikrein. Strongly blots prekallikrein and kallikrein under non-reducing and reducing conditions. Binding epitope is on the light chain of kallikrein. IgG fraction purified by immobilized Protein G. Clone 20E7-B7, isotype IgG2b.0.1 mg3400mol-innov2021
PK20E7-BIOBiotin labeled mouse monoclonal antibody to human prekallikrein. Strongly blots prekallikrein and kallikrein under non-reducing and reducing conditions. Binding epitope is on the light chain of kallikrein. IgG fraction purified by immobilized Protein G. Clone 20E7-B7, isotype IgG2b.0.1 mg5185mol-innov2021
PK3A10Mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a capture antibody in ELISA assays. Clone 3A10-C8B4, isotype IgG1 Kappa. Shares a partial epitope with PK11H4 as determined by competitive ELISA. Does not compete with PK5G7, PK7G2, PK13G5, or PK14E3. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK3A10-BIOBiotin labeled mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 3A10-C8B4, isotype IgG1 Kappa. Shares a partial epitope with PK11H4 as determined by competitive ELISA. Does not compete with PK5G7, PK7G2, PK13G5, or PK14E3.  Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PK5G7Mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 5G7-F7D7, isotype IgG1 Kappa. Shares a partial epitope with PK7G2 as determined by competitive ELISA. Does not compete with PK3A10, PK11H4, PK13G5, or PK14E3. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK5G7-BIOBiotin labeled mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 5G7-F7D7, isotype IgG1 Kappa. Shares a partial epitope with PK7G2 as determined by competitive ELISA. Does not compete with PK3A10, PK11H4, PK13G5, or PK14E3. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PK7G2Mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Can be used as a capture antibody in ELISA assays. Clone 7G2-C4C3, isotype IgG1 Kappa. Does not compete with PK3A10, PK5G7, PK11H4, PK13G5, or PK14E3  as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg5185mol-innov2021
PK7G2-BIOBiotin labeled mouse monoclonal antibody to mouse prekallikrein produced in a prekallikrein knockout mouse. IgG fraction purified by immobilized Protein A/G. Strongly detects mouse prekallikrein in ELISA and western blot under non-reducing conditions. Clone 7G2-C4C3, isotype IgG1 Kappa. Does not compete with PK3A10, PK5G7, PK11H4, PK13G5, or PK14E3 as determined by competitive ELISA. Try 20 ug of each unique antibody by ordering our Anti Mouse Prekallikrein MAb Sample Pack.0.1 mg6035mol-innov2021
PLG11B5B2Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein G. Detects plasminogen and plasmin under non-reducing and reducing conditions. Epitope localized to the heavy chain. Clone 11B5-B2, isotype IgG1kappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG13C3B10Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein G. Detects plasminogen and plasmin under non-reducing and reducing conditions. Epitope localized to the light chain. Clone 13C3-B10, isotype IgG1kappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG1C10F2Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein G. Detects plasminogen and plasmin under non-reducing and reducing conditions. Epitope localized to the light chain. Clone 1C10-F2, isotype IgG1kappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG2F6C6Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein A.  Detects plasminogen and plasmin under non-reducing and reducing conditions. Epitope localized to the light chain. Clone 2F6-C6, isotype IgG2bkappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG4G6B11Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein G. Detects plasminogen and plasmin under non-reducing and reducing conditions. Epitope localized to the light chain. Clone 4G6-B11, isotype IgG1kappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG9F9C4Mouse monoclonal antibody to human plasminogen. IgG fraction purified by immobilized Protein G. Detects plasminogen and plasmin under non-reducing conditions. Epitope localized to Kringle 1 on the heavy chain. Clone 9F9-C4, isotype IgG1kappa.<br><br> 
<a href=http://www.mol-innov。。com/promopage/plasminogen-monoclonals.html>Click here to compare all our monoclonal antibodies to human plasminogen</a><br>
1.0 mg8670mol-innov2021
PLG-MABPACK100 ug of each of PLG9F9C4, PLG11B5B2, PLG2F6C6, PLG1C10F2, PLG13C3B10, and PLG4G6B11.1 pack8670mol-innov2021
POPAIPorcine (pig) PAI-1 displays a close homology to bovine and human PAI-1 with 90 and 86percent amino acid homology, respectively.0.5 mg12155mol-innov2021
POPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active porcine PAI-1 (pig PAI-1) in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration level of PAI-1 activity in porcine plasma was reported to be 34 ng/ml in male and 42 ng/ml in female. The assay measures active PAI-1 in the 0.05-50 ng/ml range. Samples giving porcine PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay. Cross-reactivity: 11.8percent rat PAI-1, 63.6percent rabbit PAI-1, 0percent mouse PAI-1, 100percent human PAI-1.</b> After appropriate washing steps, anti-porcine PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Urokinase-Coated-Plate>uPA Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a>
1 Kit8075mol-innov2021
POPAI-TPAPorcine (pig) tPA is reacted with an excess of active wild type porcine PAI-1 at physiological pH. The resulting 1:1 molar complex is purified from the remaining PAI-1 by affinity chromatography with immobilized antibodies to human tPA.0.05 mg6885mol-innov2021
POPAITPAKT-COMTissue-type plasminogen activator (tPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. Plasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system and forms a 1:1 covalent complex with tPA and uPA. The sensitive quantitative measurement of total porcine PAI-1 tPA complex antigen in plasma, serum, cell culture media, or tissue extract samples is easily performed with this 96 well strip format ELISA kit. Concentration of PAI-1 tPA complex was found to be 10.2 ng/ml in normal porcine plasma and 37.7 ng/ml in normal porcine serum. The assay measures PAI-1 tPA complex in the 0.2-200 ng/ml range. <b>Free tPA and PAI-1 will not be detected by this assay.</b> Plasma and serum samples should be applied directly to the plate without dilution for best results. Porcine tPA will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, anti-human PAI-1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 tPA complex in the samples. A standard calibration curve is prepared in PAI-1 depleted plasma using dilutions of purified PAI-1 tPA complex and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8415mol-innov2021
POPLGPrepared from fresh porcine (pig) plasma by immobilized lysine chromatography. Please inquire about the availability of active porcine plasmin.1.0 mg4080mol-innov2021
PPACKPhe-Pro-Arg-CMK (FPRCK). Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, urokinase, Factor VIIa, and Factor XIa.5.0 mg2890mol-innov2021
PPACK2Phe-Phe-Arg-CMK (FFRCK). Potent and specific irreversible inhibitor of plasma and glandular kallikreins. Inhibits the cleavage of atrial naturiuretic peptide (ANP 1-126) by kallikreins. Also inhibits adrenal kininogenase, a kallikrein-like enzyme.10 mg5865mol-innov2021
PPACK-BIOBiotinylated Phe-Pro-Arg-CMK (FPRCK). Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, urokinase, Factor VIIa, and Factor XIa.1.0 mg8840mol-innov2021
PPACK-FITCFluorescein labeled Phe-Pro-Arg-CMK (FPRCK). Extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry. Can also be used to inhibit tissue plasminogen activator, urokinase, Factor VIIa, and Factor XIa.1.0 mg10625mol-innov2021
PPEChromatographically prepared from the euglobin fraction of porcine pancreas by the method of Lewis et al. (1) then twice crystallized. Supplied as a salt free lyophilized powder that is free of trypsin and chymotrypsin. 95percent pure by SDS-PAGE. Reconstitute with 0.05M Na Acetate 0.1M NaCl pH 5.0 to 1 mg/ml or desired concentration, aliquot and freeze remaining portion. Assay: 5-10 ug in 0.1M Tris pH 8.8 at 37 C containing 0.2mM Suc-(Al)3-pNA.<br>
References<br>
1. Lewis, U.J. et al. (1956) J. Biol. Chem. 22:705
10 mg3910mol-innov2021
PPN-IImmobilized porcine pepsin is ideal for digestion of IgG to generate F(ab')2 fragments. Pepsin is a non-specific endopeptidase that cleaves peptide bonds preferentially at aromatic residues such as tyrosines and phenylalanine. It generally does not cleave at alanine, glycine or valine residues.<br><br> 
<u>Immobilized Pepsin Digestion Protocol</u><br> 
1. Make a digestion buffer consisting of 0.2M Sodium Acetate, pH 4.4 (or other suitable buffer).<br> 
2. If IgG is salt free dissolve 10 mg of your protein sample in 1ml digestion buffer, otherwise dialyze IgG against digestion buffer then concentrate to 10mg/ml.<br> 
3. Wash 0.25ml of resuspended immobilized pepsin slurry with 2x4ml of digestion buffer. Separate the gel from the buffer after each wash by centrifugation or by column. Discard buffer after each wash.<br> 
4. Resuspend the washed immobilized pepsin gel in 0.5ml of digestion buffer then add 1ml of your protein sample to the resin.<br> 
5. Incubate mixture in a shaking water bath for 4-5 hours at 37C with rapid agitation.<br> 
6. Separate the immobilized pepsin gel from the digestion mixture as noted in step 3. Retain supernatant as your pepsin-digested protein sample.<br> 
7. Maximum fragment recovery can be obtained by washing immobilized pepsin with 1-2ml of 0.01M Tris-HCl, pH 7.5. Add wash to digest recovered in step 6. Used immobilized pepsin resin should be discarded and not reused.<br><br> 
<u>Note</u>: Optimization of immobilized pepsin protocol is required for specific applications, antibody species, and subclasses. Recommended reaction conditions are pH 1 to 4.5 at 20C to 37C. The reaction rate will be increased by increasing the enzyme to protein substrate ratio and incubation temperature.
5.0 ml3060mol-innov2021
PREN4B5E3Inhibitory mouse monoclonal antibody directed to human prorenin (Patent Pending). This antibody recognizes and binds only to prorenin. It does not bind or otherwise interact with active renin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin (unpublished data). Binding epitope is within amino acid residues 30-43 (MARLGPEWSQPMKR) of prorenin. Strongly blots prorenin under non-reducing and reducing conditions. No cross reactivity with mouse or rat prorenin. IgG fraction purified by immobilized Protein A. Clone 4B5-E3, isotype IgG2b.0.1 mg2465mol-innov2021
PREN4B5E3-BIOBiotin labeled inhibitory mouse monoclonal antibody directed to human prorenin (Patent Pending). This antibody recognizes and binds only to prorenin. It does not bind or otherwise interact with active renin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin (unpublished data). Binding epitope is within amino acid residues 30-43 (MARLGPEWSQPMKR) of prorenin. Strongly blots prorenin under non-reducing and reducing conditions. No cross reactivity with mouse or rat prorenin. IgG fraction purified by immobilized Protein A. Clone 4B5-E3, isotype IgG2b.0.1 mg7310mol-innov2021
PREN4B5E3-FITCFITC labeled inhibitory mouse monoclonal antibody directed to human prorenin (Patent Pending). This antibody recognizes and binds only to prorenin. It does not bind or otherwise interact with active renin. Blocks proteolytic conversion of prorenin to renin by catalytic amounts of trypsin (unpublished data). Binding epitope is within amino acid residues 30-43 (MARLGPEWSQPMKR) of prorenin. Strongly blots prorenin under non-reducing and reducing conditions. No cross reactivity with mouse or rat prorenin. IgG fraction purified by immobilized Protein A. Clone 4B5-E3, isotype IgG2b.0.1 mg7310mol-innov2021
PREN6E2B7Mouse monoclonal antibody directed to human prorenin. This antibody recognizes and binds to prorenin only. Binding epitope is within amino acid residues 16-29 (MPSIRESLKERGVD) of prorenin. Strongly blots prorenin under non-reducing conditions only. Cross reacts with canine prorenin due to a common epitope. No cross reactivity with mouse or rat prorenin. Clone 6E2-B7. IgG1 class.0.1 mg2465mol-innov2021
PREN7D3E3Mouse monoclonal antibody directed to human prorenin. This antibody recognizes and binds to prorenin and renin. Binding epitope has not yet been determined but resides within the renin sequence. Clone 7D3-E3. IgG1 class.0.1 mg2465mol-innov2021
PRL11F9Mouse monoclonal antibody to human Prolactin. Strongly blots prolactin under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 11F9D5, isotype IgG1.0.1 mg3400mol-innov2021
PRL13G4Mouse monoclonal antibody to human Prolactin. Strongly blots kininogen under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 13G4C7, isotype IgG1.0.1 mg3400mol-innov2021
PRL16F4Mouse monoclonal antibody to human Prolactin. Strongly blots kininogen under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 16F4E9G10, isotype IgG1.0.1 mg3400mol-innov2021
PRL3F6Mouse monoclonal antibody to human Prolactin. Strongly blots prolactin under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 3F6G11, isotype IgG1.0.1 mg3400mol-innov2021
PRL3G11Mouse monoclonal antibody to human Prolactin. Strongly blots kininogen under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 3G11B6E8, isotype IgG1.0.1 mg3400mol-innov2021
PRL5F3Mouse monoclonal antibody to human Prolactin. Strongly blots prolactin under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 5F3E4, isotype IgG1.0.1 mg3400mol-innov2021
PRL7C11Mouse monoclonal antibody to human Prolactin. Strongly blots kininogen under non-reducing and reducing conditions.  IgG fraction purified by immobilized Protein G. Clone 7C11E2F3, isotype IgG1.0.1 mg3400mol-innov2021
PSA14E7Mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 14E7-E5, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
PSA14E7-BIOBiotin labeled mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 14E7-E5, isotype IgG1 Kappa.0.1 mg10030mol-innov2021
PSA16G3Mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 16G3-C7E10, isotype IgG1 Kappa.0.1 mg3400mol-innov2021
PSA18D11Mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 18D11-E9B4, isotype IgG2b.0.1 mg3400mol-innov2021
PSA18D4Mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 18D4-B5D4, isotype IgG2b.0.1 mg3400mol-innov2021
PSA18D4-BIOBiotin labeled mouse monoclonal antibody to human PSA. IgG fraction purified by immobilized Protein G. Detects Prostate Specific Antigen under non-reducing conditions. Clone 18D4-B5, isotype IgG1 Kappa.0.1 mg10030mol-innov2021
PTPARecombinantly produced in insect cells. >95percent active. For ELISA and Western Blotting of pig tPA, please use our Rabbit Polyclonal Antibodies to Human tPA or our Mouse Monoclonal to Human tPA which cross react.0.1 mg5695mol-innov2021
PTPAKTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of functionally active porcine tPA (pig tPA) in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The basal level of tPA activity in a small sample of pigs was found to be 2 IU/ml. 1 tPA IU = 1.64 ng. The normal concentration of tPA antigen in a porcine model of cardiopulmonary bypass was 1.69 ng/ml. The concentration of tPA antigen in a porcine model of sepsis was 8.9-15.9 ng/ml depending on collection site. The assay measures active tPA in the 0.02-10 ng/ml range. Samples giving porcine tPA levels above 10 ng/ml should be diluted in blocking buffer before use. Samples of plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active tPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the diluent provided in the kit. Serum and cell culture media at neutral pH may also be used. Functionally active tPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Complexed tPA will not bind to the PAI-1 and will not be detected by the assay.</b> After appropriate washing steps, anti-porcine tPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active tPA in the samples. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
PUPAActive two-chain porcine urokinase (uPA), recombinantly produced in insect cells.0.05 mg4590mol-innov2021
PVNPrepared from fresh porcine (pig) plasma using urea as a denaturant.0.1 mg3995mol-innov2021
PYFIPyFi High Fidelity DNA Polymerase is a recombinant thermostable enzyme cloned from a species of thermophilic Pyrococcus archaebacterium. PyFi contains an integral 3’-5’ proofreading capability that increases the fidelity to over 6X that of Taq DNA polymerase. PyFi is more sensitive than some leading competitors and create products with blunt ends. Suitable for Standard Endpoint PCR, Blunt End Cloning, and Mutagenesis of DNA templates up to 5kb. PyFi undergoes extensive quality control and is free of contaminating endonucleases. Includes 10X reaction buffer.200 units2040mol-innov2021
QMIXTaqCelerate qPCR Master Mix is a ready-to-use, hot-start master mix containing TealReveal Dye, dNTPs, MgCl2, and TaqTivate Hot Start DNA Polymerase. TealReveal is a dsDNA-binding dye that is non-mutagenic, non-cytotoxic, impermeable to the cell membrane and safe for aquatic life. TealReveal will not inhibit reactions and is compatible with traditional SYBR Green filters. Chemically modified TaqTivate requires a 95C activation time of only two minutes for faster cycling reactions. TaqCelerate qPCR Master Mix is supplied in a 2X formulation that requires only the addition of primers, template and water. Separate ROX passive fluorescent reference dye is included.100 rxn2720mol-innov2021
RAPProduced recombinantly in <i>E. Coli</i>. Suitable to block receptor function in uptake assays. Contains endotoxin which might trigger signaling events.0.5 mg9775mol-innov2021
RAP-FITCProduced recombinantly in <i>E. Coli</i> and labeled with FITC at primary amines.0.1 mg4335mol-innov2021
RAP-LEThis preparation of Receptor Associated Protein is purified to lower levels of endotoxin. Low endotoxin RAP is suitable for experiments involving signaling events and phosphorylation studies, which may be triggered by endotoxin.0.5 mg12155mol-innov2021
RAP-SMThis stable mutant form of human Receptor Associated Protein (RAP) is resistant to both pH and heat induced denaturation. The molecule binds to lipoprotein receptor-related protein 1 (LRP1) with high affinity and inhibits LRP1 function both <i>in vitro</i> and <i>in vivo</i>. The D3 domain of RAP, which unfolds at low pH causing dissociation from LRP1, has been stabilized with six mutations (1). Y260 and T297 are changed to cysteines to generate a novel disulfide bond between helices 2 and 3 while H257, H259, H268, and H290 are changed to phenylalanines. Human RAP Stable Mutant does not unfold at pH 5.5 and has a melting temperature of 73°C, more than 30 degrees above that of wild type RAP. It is also more resistant to trypsin and chymotrypsin mediated proteolysis. Human RAP Stable Mutant may be useful in multiple pathological settings where LRP1 blockade has shown to be effective. Produced recombinantly in <i>E. coli</i>. Endotoxin reduced by reverse-phase chromatography for cell based experiments and animal studies. 
 
References 
1. Joni M. Prasad, Mary Migliorini, Rebeca Galisteo, and Dudley K. Strickland. Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain. J. Biol. Chem. 2015 290: 17262-17268.
0.5 mg12155mol-innov2021
RATIIIPrepared from fresh rat plasma using several chromatographic steps.1.0 mg6460mol-innov2021
RBATIIIPrepared from fresh rabbit plasma using several chromatographic steps.1.0 mg6460mol-innov2021
RBD-HISSARS-CoV-2 is the novel coronavirus that causes CoronaVirus Disease 2019 (COVID-19). The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein binds to the cell receptor ACE2 allowing viral entry and infection. It is a 223 amino acid glycoprotein representing residues 319-541 of the spike protein S1 sequence. RBD from Molecular Innovations is useful for capturing SARS-CoV-2 specific antibodies from human plasma and serum in COVID-19 serological assays. Recombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 6X-Histidine tag at C terminus for purification.<br> 
Produced under license from the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
0.05 mg4505mol-innov2021
RBD-ISARS-CoV-2 is the novel coronavirus that causes CoronaVirus Disease 2019 (COVID-19). The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein binds to the cell receptor ACE2 allowing viral entry and infection. It is a 223 amino acid glycoprotein representing residues 319-541 of the spike protein S1 sequence. Immobilized RBD from Molecular Innovations is useful for capturing SARS-CoV-2 specific antibodies from human plasma and serum. Immobilized RBD of SARS-CoV-2 Spike Protein is highly specific and reusable. Recombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 6X-Histidine tag at C terminus for purification.<br> 
Produced under license from the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
0.1 ml11815mol-innov2021
RbFBGNPrepared from fresh rabbit plasma using several chromatographic steps.  Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.25 mg4590mol-innov2021
RbFBGN-FITCRabbit fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh rabbit plasma using several chromatographic steps.  Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.10 mg4420mol-innov2021
RBFBGNKTFibrinogen is a soluble glycoprotein that circulates in the blood and is converted to insoluble fibrin by thrombin in the final step of the coagulation cascade. Hepatic expression of fibrinogen increases two to four hundred fold during the acute phase response to infection or inflammation. Elevated fibrinogen levels are correlated with cardiovascular disease and atherosclerosis. The sensitive quantitative measurement of rabbit fibrinogen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. Fibrinogen is present in normal rabbit plasma at a concentration of 3.07 mg/ml. The assay measures total rabbit fibrinogen in the 0.5-500 ng/ml range. Samples giving rabbit fibrinogen levels above 500 ng/ml should be diluted in 1X diluent before use. A 1:500,000 to 1:1,000,000 dilution for plasma or serum is suggested for best results. Rabbit fibrinogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rabbit fibrinogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of fibrinogen in the samples. A standard calibration curve is prepared using dilutions of purified fibrinogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>
1 kit8415mol-innov2021
RB-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.500 mg3400mol-innov2021
RB-GF-BIORabbit IgG purified from normal serum by immobilized Protein A then biotin labeled. >95 percent pure by SDS-PAGE and preservative free.1.0 mg3400mol-innov2021
RB-GF-EDPurified from normal serum by immobilized Protein A using low endotoxin methodology and sterile filtered. >95 percent pure by SDS-PAGE and preservative free. Add deionized water to original volume, aliquot and freeze unused portion.50 mg6885mol-innov2021
RB-GF-FITCRabbit IgG purified from normal serum by immobilized Protein A then FITC labeled. >95 percent pure by SDS-PAGE and preservative free.1.0 mg3400mol-innov2021
RBIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total rabbit IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react with human, pig, rat, dog, sheep or mouse. It cross reacts with guinea pig at 0.002 percent.</b> The concentration of IgG in normal rabbit serum ranges from 5 to 12 mg/ml. The assay measures rabbit IgG in the 0.1-100 ng/ml range. Samples giving rabbit IgG levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000 to 1:10,000,000 dilution for serum is suggested for best results. Rabbit IgG will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-rabbit IgG primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of rabbit IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rabbit IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6885mol-innov2021
RbPAI-I91LThis stable mutant of rabbit PAI-1 contains a single conservative mutation (Isoleucine 91 to Leucine) that yields PAI-1 with an enhanced half-life as compared to the wild type.0.5 mg12155mol-innov2021
RbPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active rabbit PAI-1 in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration of PAI-1 activity was reported to be 9.8 ng/ml in rabbit plasma and 2.9 ng/ml in rabbit serum. The assay measures active PAI-1 in the 0.05-50 ng/ml range. Samples giving rabbit PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay.</b> After appropriate washing steps, anti-rabbit PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br><br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Urokinase-Coated-Plate>uPA Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a>
1 Kit8075mol-innov2021
RbPAIKT-TOTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of total rabbit PAI-1 antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration of PAI-1 antigen was reported to be 20.5 ng/ml in rabbit plasma and 11.8 ng/ml in rabbit serum. The assay measures total PAI-1 in the 0.07-67 ng/ml range. Samples giving rabbit PAI-1 levels above 67 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Rabbit PAI-1 will bind to the capture antibody coated on the microtiter plate. <b>Free, latent, and complexed PAI-1 will be detected by the assay.</b> After appropriate washing steps, anti-rabbit PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 Kit8075mol-innov2021
RbPAI-LLatent rabbit PAI-1 is a useful control for experiments when used in conjunction with the active form.0.5 mg12155mol-innov2021
RbPAI-L-BIOThis latent fraction of recombinant rabbit PAI-1 is biotin labeled on lysine residues.0.5 mg12155mol-innov2021
RbPLA-BACL2Barium chloride (BaCl2) precipitation of plasma is a fractionation method that enriches for Vitamin K dependent proteins, such as coagulation factors prothrombin and Factor X. After BaCl2 precipitation, the fraction is dialyzed against TBS and lyophilized. 
 
Molecular Innovations offers lyophilized BaCl2 fractions with each vial containing precipitate obtained from 50 ml of rabbit plasma. Protein concentration is approximately 6 mg per vial. 
 
Please contact us about lyophilized plasma BaCl2 precipitates from other species including mouse, rat, hamster and monkey. The animals used for this material are of US Origin, ensuring that only the highest-quality material is used.
50 ml2550mol-innov2021
RbPLA-SC-PAIPrepared from frozen rabbit plasma using immobilized anti-rabbit PAI-1 IgG.10 ml6035mol-innov2021
RbPLGPrepared from fresh rabbit plasma by immobilized lysine chromatography.1.0 mg6035mol-innov2021
RbPLMPrepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg7565mol-innov2021
RbSAAlbumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. Prepared from rabbit plasma by proprietary fractionation methods and lyophilized. >95percent pure by SDS-PAGE.  Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.500 mg3400mol-innov2021
RbTPARabbit tPA recombinantly produced in insect cells which is >95percent active.0.1 mg5695mol-innov2021
RbTPAKTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of functionally active rabbit tPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. In-house testing of pooled normal rabbit plasma in citrate indicates a tPA concentration of 0.5-1 ng/ml. The assay measures active tPA in the 0.05-20 ng/ml range. Samples giving rabbit tPA levels above 20 ng/ml should be diluted in blocking buffer before use. Samples of plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active tPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the 10X TBS provided in the kit. Serum and cell culture media at neutral pH may also be used. Functionally active tPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Complexed tPA will not bind to the PAI-1 and will not be detected by the assay.</b> After appropriate washing steps, anti-rabbit tPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active tPA in the samples. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br><br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>
1 kit8415mol-innov2021
RbUPAActive two-chain rabbit urokinase (uPA), recombinantly produced in insect cells.0.05 mg5015mol-innov2021
RbVNPrepared from fresh rabbit plasma using urea as a denaturant.0.1 mg3995mol-innov2021
RFBGNPrepared from fresh rat plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg4420mol-innov2021
RFBGN-FITCRat fibrinogen amino terminal labeled with fluorescein isothiocyanate (FITC). Prepared from fresh rat plasma using several chromatographic steps. Plasminogen depleted by lysine affinity chromatography. Thaw in a 37&deg;C water bath without agitation until completely liquid, then gently mix before use. Keep fibrinogen at 25-37&deg;C, aliquot and flash freeze unused portion.1.0 mg8755mol-innov2021
RFBGNKTFibrinogen is a soluble glycoprotein that circulates in the blood and is converted to insoluble fibrin by thrombin in the final step of the coagulation cascade. Hepatic expression of fibrinogen increases two to four hundred fold during the acute phase response to infection or inflammation. Elevated fibrinogen levels are correlated with cardiovascular disease and atherosclerosis. The sensitive quantitative measurement of rat fibrinogen in plasma and serum samples is easily performed with this 96 well strip format ELISA kit. Fibrinogen is present in normal rat plasma at a concentration of 3.1 mg/ml and varies by age and diet. The assay measures total rat fibrinogen in the 3.125-800 ng/ml range. Samples giving rat fibrinogen levels above 800 ng/ml should be diluted in 1X diluent before use. A 1:10,000 to 1:50,000 dilution for plasma or serum is suggested for best results. Rat fibrinogen will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rat fibrinogen primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated avidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of fibrinogen in the samples. A standard calibration curve is prepared using dilutions of purified fibrinogen and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-Fibrinogen-Antigen-Capture-Plate>Rat Fibrinogen Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Avidin-HRP-Labeled>Avidin-HRP</a>
1 kit5185mol-innov2021
RFIIRat prothrombin is prepared from fresh frozen rat plasma. Purity is determined by SDS-PAGE analysis.0.1 mg3740mol-innov2021
RFIXRat factor IX is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography. Purity is determined by SDS-PAGE analysis and activity is measured using a factor IX clotting assay.0.05 mg6460mol-innov2021
RFIXAFactor IXa is prepared from highly purified factor IX by activation with factor XIa. The factor IXa is further purified by gel filtration, followed by immunoaffinity purification. Purity is assessed by SDS-PAGE analysis. Activity is determined in a one-stage clotting assay.0.05 mg8755mol-innov2021
RFXRat factor X is prepared from fresh frozen plasma by a combination of conventional procedures and immunoaffinity chromatography. Purity is determined by SDS-PAGE analysis and activity is measured using a factor X clotting assay.0.1 mg11220mol-innov2021
RFXAFactor Xa is prepared from homogenous Factor X by activation with Russell's viper venom. The venom is removed after activation. Purity is determined by SDS-PAGE analysis and activity is measured in a factor Xa clotting assay and/or chromogenic substrate assay. Thaw rapidly in a 37C water bath without allowing protein to warm to 37C and immediately cool on ice.0.1 mg10625mol-innov2021
RFXIIRecombinant insect cell derived rat Factor XII is a single chain glycoprotein purified by ion exchange chromatography. Factor XII is converted, principally from the action of kallikrein, into an active serine protease (Factor &#945;-XIIa) that functions in the in vivo initiation of blood coagulation, fibrinolysis, and kinin formation. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Custom mutants of Factor XII are also available, please contact us for more details.0.1 mg6885mol-innov2021
RFXIIARat Factor &#945;-XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system of blood coagulation. Recombinant insect cell derived rat Factor &#945;-XIIa is manufactured by activation of recombinant rat Factor XII with human kallikrein followed by removal of the activator. >95percent activation is observed on SDS-PAGE. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma. Custom mutants of Factor XII are also available, please contact us for more details.0.1 mg7820mol-innov2021
RFXIIKT-TOTFactor XII (aka Hageman Factor) is a single-chain, 615 amino acid glycoprotein zymogen. Factor XII is activated by kallikrein. Factor XIIa converts prekallikrein to kallikrein during the intrinsic pathway of the coagulation cascade. Although Factor XII is not thought to play an essential role in normal hemostasis, lack of Factor XII in a mouse model resulted in a severe defect in thrombus formation. The sensitive quantitative measurement of total rat Factor XII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. <b>Factor XII and XIIa will be detected by the assay.</b> The concentration of Factor XII in normal human plasma ranges from 15-47 ug/ml. Normal values of Factor XII in rat plasma have not been conclusively determined but are believed to be similar to human plasma based on in-house testing. The assay measures total rat Factor XII in the 0.01-10 ng/ml range. Samples giving rat Factor XII levels above 10 ng/ml should be diluted in blocking buffer before use. A 1:10,000 to 1:100,000 dilution for plasma is suggested for best results. Rat Factor XII will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rat Factor XII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with streptavidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of Factor XII in the samples. A standard calibration curve is prepared using dilutions of purified Factor XII and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit8415mol-innov2021
RPAIRecombinant rat PAI-1 is the ideal choice for studies involving this animal model of fibrinolysis and cancer studies. The active fraction typically contains 95percent active PAI-1.0.5 mg12155mol-innov2021
RPAI-AF488Recombinant rat PAI-1 is labeled with Alexa Fluor 488 at primary amines (Abs: 495, Em: 519). This wild type fraction typically contains 70percent active PAI-1.0.5 mg13855mol-innov2021
RPAI-BIORecombinant rat PAI-1 is labeled with biotin at primary amines. This wild type fraction typically contains 50percent active PAI-1.0.5 mg12155mol-innov2021
RPAI-I91LThis recombinant rat PAI-1 has a single conservative mutation (Isoleucine 91 to Leucine) that yields a rat PAI-1 with an enhanced half-life as compared to the wild type.0.5 mg12155mol-innov2021
RPAI-I91L-BIOThis recombinant rat PAI-1 has a single conservative mutation (Isoleucine 91 to Leucine) for increased half-life and is biotin labeled on lysine residues.0.5 mg12155mol-innov2021
RPAIKTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis. The sensitive quantitative measurement of functionally active rat PAI-1 in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration level of PAI-1 activity in rat plasma was found to be 1.0 ng/ml. The assay measures active PAI-1 in the 0.05-50 ng/ml range. Samples giving rat PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Functionally active PAI-1 reacts with urokinase coated onto a micro titer plate. <b>Latent or complexed PAI-1 will not bind to the plate and will not be detected by the assay. Cross-reactivity: 12percent porcine PAI-1, 100percent mouse PAI-1.</b> After appropriate washing steps, anti-rat PAI-1 primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of PAI-1 in the samples. A standard calibration curve is prepared using dilutions of purified PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.<br><br>Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Urokinase-Coated-Plate>uPA Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>1 Kit8075mol-innov2021
RPAIKT-TOTPlasminogen activator inhibitor type 1 (PAI-1) is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases. Levels of PAI-1 increase with age and are elevated in conditions such as normal pregnancy and sepsis.  The sensitive quantitative measurement of total rat PAI-1 antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The concentration level of PAI-1 antigen in rat plasma was found to be 1.8 ng/ml. The assay measures rat PAI-1 in the 0.05-50 ng/ml range. Samples giving rat PAI-1 levels above 50 ng/ml should be diluted in blocking buffer before use. Normal plasma should be applied directly to the plate for best results. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1. Rat PAI-1 will bind to the capture antibody coated on the microtiter plate. <b>Free, latent, and complexed PAI-1 will be detected by the assay.</b> After appropriate washing steps, biotin labeled anti-rat PAI-1 primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of rat PAI-1 in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rat PAI-1 and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br> 
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Rat-PAI-1-Antigen-Capture-Plate>Rat PAI-1 Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8075mol-innov2021
RPAI-LLatent rat PAI-1 is a useful control for experiments when used in conjunction with the active form or stable mutant.0.5 mg12155mol-innov2021
RPAI-L-AF488Recombinant rat PAI-1 is labeled with Alexa Fluor 488 at primary amines (Abs: 495, Em: 519). This latent wild type fraction contains <1percent active PAI-1.0.5 mg13855mol-innov2021
RPAI-L-BIOBiotin labeled latent rat PAI-1 is a useful control for experiments involving the biotinylated stable mutant.0.5 mg12155mol-innov2021
RPAI-P1NBDP1'-NBD rat PAI-1 was created by mutagenesis of the methionine residue (Met348) at the P1-P1' scissile bond to cysteine. This provides a free thiol group for labeling with NBD, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-NBD PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase. This unique product is an ideal reagent for researchers studying PAI-1 behavior in rat models.0.5 mg15640mol-innov2021
RPAI-P9NBDP9-NBD Rat PAI-1 was created by mutagenesis of the P9 serine residue (Ser339) on the reactive center loop to cysteine. This provides a free thiol group for incorporation of N,N'-dimethyl-N-(acetyl)-N'-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) (NBD), a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P9-NBD PAI-1 is enhanced 6-7 fold upon insertion of the reactive center loop into beta-sheet A following complex formation with proteinases, formation of the latent species, or cleavage by elastase. The incorporated probe is excited at 480 nm and displays a broad emission spectrum with a peak centered 542 nm with a resultant blue-shift to 520 nm following reactive center loop insertion. This unique product is an ideal reagent for researchers studying PAI-1 behavior in rat models.0.5 mg15640mol-innov2021
RPAI-TOT-PLATE96 well plate with 8 removable strips coated with monoclonal antibody to rat Plasminogen Activator Inhibitor (PAI-1) at 100 ul/well and blocked with 300 ul/well. Ideal for specific binding of rat PAI-1 antigen for sandwich style ELISA experiments.1 plate2210mol-innov2021
RPEChromatographically prepared from the euglobin fraction of pancreas by the method of Lewis et al. (1) then twice crystallized. Supplied as salt free lyophilized powder. The protein is stable 9-12 months when stored at 5 C and does not contain trypsin or chymotrypsin. 95percent pure by SDS-PAGE. Reconstitute with 0.05M Na Acetate 0.2M NaCl pH 5.0 to 1 mg/ml or desired concentration, aliquot and freeze remaining portion.<br>
Assay: 5-10 ug in 0.1M Tris pH 8.8 at 37 C containing 0.2mM Suc-(Al)3-pNA.<br>
References: 1. Lewis, U.J. et al. (1956) J. Biol. Chem. 22:705
0.1 mg5780mol-innov2021
RPLA-EDTA-ANG-FIn the renin-angiotensin system (RAS), renin activates angiotensinogen to yield angiotensin I, which is further converted into angiotensin II by angiotensin-converting enzyme. Removal of the kidney generates renin/prorenin deficient plasma with high levels of angiotensinogen. This nephrectomized rat plasma can be used as a source of angiotensinogen or as a substrate for renin generation of Ang I. Plasma is collected from female rats at least 48 hours post nephrectomy. The substrate activity is determined by incubation with renin followed by Ang I radio-immune assay (RIA).1.0 ml8670mol-innov2021
RPLA-EDTA-ANG-MIn the renin-angiotensin system (RAS), renin activates angiotensinogen to yield angiotensin I, which is further converted into angiotensin II by angiotensin-converting enzyme. Removal of the kidney generates renin/prorenin deficient plasma with high levels of angiotensinogen. This nephrectomized rat plasma can be used as a source of angiotensinogen or as a substrate for renin generation of Ang I. Plasma is collected from male rats at least 48 hours post nephrectomy. The substrate activity is determined by incubation with renin followed by Ang I radio-immune assay (RIA).<br><br> 
<b>Also available:</b><br> 
Rat Prorenin/Renin Total Antigen Assay (<a href=http://www.mol-innov。。com/item/Rat-Prorenin-Renin-Total-Antigen-ELISA-Kit>RPRENKT-TOT</a>)<br> 
Rat Prorenin (<a href=http://www.mol-innov。。com/item/Rat-Prorenin-C-terminal-8x-His-tag>RPREN-HIS</a>)<br> 
Polyclonal Antibodies (<a href=http://www.mol-innov。。com/subcat/Polyclonal-Antibodies-to-Rat-and-Mouse-Prorenin-Renin> Click here for list</a>)<br> 
Rat Renin/Prorenin Double Depleted Plasma (<a href=http://www.mol-innov。。com/item/Rat-Renin-Prorenin-Double-Depleted-Plasma>RPLA-SC-PREN</a>)<br> 
Rat Renin Substrate Plasma, Female, Sodium EDTA (<a href=http://www.mol-innov。。com/item/Rat-Renin-Substrate-Plasma-Female-Sodium-EDTA>RPLA-EDTA-ANG-F</a>)<br>
1.0 ml8670mol-innov2021
RPLA-SCNormal US origin rat plasma (Na Citrate). Control for PAI-1 depleted rat plasma.10 ml2550mol-innov2021
RPLA-SC-LPrepared from frozen rat plasma by extended incubation at 37 C.10 ml3400mol-innov2021
RPLA-SC-PAIPrepared from frozen rat plasma using immobilized anti-rat PAI-1 IgG.10 ml6970mol-innov2021
RPLA-SC-PRENPrepared from frozen rat plasma using immobilized anti-human Renin IgG.10 ml5525mol-innov2021
RPLA-SER-GFPrepared from frozen US origin Sprague Dawley rat serum using immobilized Protein A and G.10 ml6970mol-innov2021
RPLGPrepared from fresh rat plasma by immobilized lysine chromatography.1.0 mg6035mol-innov2021
RPLMPrepared from plasminogen by activation with immobilized human uPA. 100 percent functionally active plasmin is purified from the activation reaction by immobilized SBTI. Plasmin will undergo rapid auto proteolysis in the absence of benzamidine and should be used quickly once thawed. Aliquot to avoid freeze-thaw cycles.1.0 mg7565mol-innov2021
RPREN1G5Mouse monoclonal antibody directed to rat prorenin. This antibody recognizes and binds to prorenin and renin. Binding epitope has not yet been determined but resides within the renin sequence. IgG fraction purified by immobilized Protein A. Clone 1G5-B8. IgG3 class.0.1 mg3400mol-innov2021
RPREN2C6Mouse monoclonal antibody directed to rat prorenin. This antibody recognizes and binds to prorenin only. Binding epitope has not yet been determined but resides within the prosegment sequence of prorenin. IgG fraction purified by immobilized Protein G. Clone 2C6-F4. IgG1 Kappa class.0.1 mg3400mol-innov2021
RPREN-HISRecombinantly produced in HEK cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at C terminus for purification. Fully activatable to renin by catalytic amounts of trypsin. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits a low level of enzymatic activity relative to renin which is generated from prorenin by proteolytic cleavage of the first ~43 amino acids at the N-terminus. This so called prosegment appears to block the full enzymatic potential of the active site (1). Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects(2).<br><br>

1) A.H. Jan Danser; Jaap Deinum ; Renin, Prorenin and the Putative (Pro)renin Receptor). Hypertension. 2005;46:1069.
<br><br>

2) Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M.
Increased plasma inactive renin in diabetes mellitus. A marker of microvascular
complications. N Engl J Med. 1985;312:1412-1417.
0.1 mg7480mol-innov2021
RPRENKT-TOTProrenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. It has been reported that the levels of circulating prorenin (but not renin) are increased in diabetic subjects. Plasma and serum concentrations increase in several conditions such as pregnancy, progressive diabetes mellitus, diabetes mellitus with microvascular disease, and diabetic retinopathy. The sensitive quantitative measurement of total rat prorenin and renin antigen in plasma, serum or cell culture supernatant samples is easily performed with this 96 well strip format ELISA kit. <b>Renin and prorenin will be detected by the assay.</b> Rat prorenin levels range from 0-400
ng/ml depending on assay methodology. The assay measures total rat prorenin in the 0.1-100 ng/ml range. Samples giving rat prorenin levels above 100 ng/ml should be diluted in blocking buffer before use. Rat prorenin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rat prorenin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with avidin conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450nm.  Color development is proportional to the concentration of prorenin in the samples. A standard calibration curve is prepared using dilutions of purified prorenin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.
1 kit8075mol-innov2021
RPRLProlactin (PRL, Mammotropin, Luterotropic hormone, Lutetropin) is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Expressed recombinantly and purified by chromatography. >95percent pure by SDS-PAGE and biologically active. Add deionized water to original volume, aliquot and freeze unused portion.0.05 mg4845mol-innov2021
RPRLKTProlactin (PRL) is a 199 aa, 23kD peptide hormone that is secreted primarily by the pituitary gland in both males and females, though its major roles are in pregnancy and lactation. Prolactin may have a role in breast cancer development, with higher prolactin levels correlating with postmenopausal breast cancer risk. The sensitive quantitative measurement of total rat prolactin antigen in plasma is easily performed with this 96 well strip format ELISA kit. The concentration of prolactin in pooled normal rat plasma determined by in house testing was 6.8 ng/ml. Prolactin levels in pregnant rats are elevated immediately before birth. The assay measures total rat prolactin in the 0.1-100 ng/ml range. Samples with rat prolactin levels above 100 ng/ml should be diluted in blocking buffer before use. Normal plasma may be applied directly to the plate or diluted 1:1 with blocking buffer. Rat prolactin will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rat prolactin primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of prolactin in the samples. A standard calibration curve is prepared using dilutions of purified prolactin and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit7905mol-innov2021
RPRLRProlactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain is expressed recombinantly and purified by chromatography. >95percent pure by SDS-PAGE and biologically active. Add deionized water to original volume, aliquot and freeze unused portion.0.02 mg4845mol-innov2021
RPRLR-FCProlactin is a neuroendocrine peptide hormone that is secreted primarily by the pituitary gland. Prolactin receptor is a class 1 cytokine transmembrane receptor that varies in size with tissue source and species. It consists of an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region. The extracellular domain (Ser21-Asp229) is expressed recombinantly, purified by chromatography, sterile filtered and lyophilized. >95percent pure by SDS-PAGE and biologically active as measured by inhibitory activity toward prolactin-induced proliferation of Nb2-11 rat lymphoma cells (Gout et al. (1980) Cancer Res. 40:2433). ED50 for this effect is typically < 50 ng/ml in the presence of 0.5 ng/ml of recombinant human Prolactin. Add deionized water to original volume, aliquot and freeze unused portion.<br> 
<img src=/img/prolactin-receptor.jpg><br> 
This <b>chiMAX Fc Fusion Protein</b> is glycosylated and expressed as a chimera with the Fc region of mouse immunoglobulin (heavy chain hinge, CH2 and CH3). Fc fusion proteins are typically more stable and resistant to degradation and clearance than native cytokines. Fc fusion proteins appear as a dimer in SDS-PAGE under non-reducing conditions.
0.1 mg5185mol-innov2021
RSAAlbumin is a water-soluble protein with considerable structural stability which makes up 60percent of the total protein of plasma. It functions as a carrier of hormones, enzymes, fatty acids, metal ions, and medicinal products. Prepared from Sprague Dawley rat plasma by proprietary fractionation methods and lyophilized. >95percent pure by SDS-PAGE.  Add deionized water or buffer to original or desired volume, aliquot and freeze unused portion.100 mg3400mol-innov2021
RSFVIIIKT-TOTFactor VIII (aka Factor VIII:C or Antihemophilic Globulin) is a glycoprotein zymogen that circulates in a stabilized non-covalent complex with von Willebrand Factor (vWF). Following activation by thrombin or Factor Xa, Factor VIIIa dissociates from vWF and catalyzes the activation of Factor X by Factor IXa in the amplification phase of coagulation. Factor VIIIa activity is quickly decreased by spontaneous dissociation and proteolytic degradation by activated Protein C, Factor Xa and Factor IXa. Hemophilia A is caused by mutations in the Factor VIII gene; a majority of patients have decreased Factor VIII plasma levels while 5% of patients have normal levels of nonfunctioning protein. The sensitive quantitative measurement of total rhesus macaque monkey (Macaca mulatta) Factor VIII antigen in plasma samples is easily performed with this 96 well strip format ELISA kit. The average normal plasma level of Factor VIII is defined as 1.0 IU/ml and the normal range is 0.4-1.8 IU/ml. Hemaophilia A patients are classified by the following Factor VIII levels: 0.05-0.25 IU/ml = mild, 0.01-0.05 IU/ml = moderate, and <0.01 IU/ml = severe. Normal values of Factor VIII in rhesus plasma have not been conclusively determined but are believed to be similar to human plasma. The assay measures total rhesus Factor VIII in the 0.001-0.48 IU/ml range. Samples giving rhesus Factor VIII levels above 0.48 IU/ml should be diluted in blocking buffer before use. 1:8 and 1:16 dilutions for normal plasma, or 1:4 and 1:8 dilutions for Haemophiliac plasma, are suggested for best results.<br><br>Rhesus Factor VIII will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled anti-rhesus Factor VIII primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. A standard calibration curve is prepared along with the samples to be measured using dilutions of rhesus plasma. Color development is proportional to the concentration of Factor VIII in the samples. All reagents and standards are provided in these ELISA kits.<br><br><strong>The Factor VIII level in the rhesus plasma standard provided is calibrated against a human plasma secondary standard that is referenced to the WHO or ISTH International Standard.</strong>1 kit8415mol-innov2021
RS-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg3400mol-innov2021
RSIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total rhesus macaque (Macaca mulatta) monkey IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react significantly with human, mouse, rat, dog, sheep, pig or rabbit IgG.</b> The concentration of IgG in normal rhesus monkey serum ranges from 5 to 12 mg/ml. The assay measures rhesus monkey IgG in the 0.1-100 ng/ml range. Samples giving rhesus monkey IgG levels above 100 ng/ml should be diluted in blocking buffer before use. A 1:1,000,000 to 1:10,000,000 dilution for serum is suggested for best results. Rhesus monkey IgG will bind to the monoclonal capture antibody coated on the microtiter plate. After appropriate washing steps, biotin labeled monoclonal anti-rhesus IgG primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with horseradish peroxidase conjugated streptavidin. Following an additional washing step, TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of rhesus monkey IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rhesus monkey IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit6545mol-innov2021
RT-GFPurified from normal serum by immobilized Protein A. >95 percent pure by SDS-PAGE and preservative free.10 mg1360mol-innov2021
RTHROMRat thrombin is prepared from purified prothrombin by activation with coastal taipan venom followed by affinity chromatography. Purity is verified by SDS-PAGE analysis and specific activity in NIH thrombin units is determined by chromogenic substrate.0.1 mg7480mol-innov2021
RTIGGKTImmunoglobulin G (IgG) is the most abundant immunoglobulin in serum and is predominately involved in the secondary immune response. The IgG subclasses are designated 1, 2, 3 and 4 based on their relative prevalence in serum. The sensitive quantitative measurement of total rat IgG antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay does not distinguish IgG subclasses. <b>The kit does not cross react significantly with mouse, human, rabbit, cyno monkey, horse, dog, sheep or pig IgG.</b> The concentration of IgG in normal rat serum ranges from 1.7 to 5.0 mg/ml. The assay measures rat IgG in the 0.2-250 ng/ml range. Samples giving rat IgG levels above 250 ng/ml should be diluted in blocking buffer before use. A 1:200,000 to 1:2,000,000 dilution for serum is suggested for best results. Rat IgG will bind to the capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-rat IgG primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of rat IgG in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rat IgG and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit3995mol-innov2021
RTIGMKTImmunoglobulin M (IgM) is the first immunoglobulin produced in the immune response and is the third most abundant immunoglobulin in serum. IgM is a disulfide-linked 970kDa pentamer that activates complement and is responsible for red blood cell agglutination. Each monomer consists of two mu heavy chains and two kappa or lambda light chains. The sensitive quantitative measurement of total rat IgM antigen in serum, plasma, hybridoma cell supernatants, ascites or other biological fluid samples is easily performed with this 96 well strip format ELISA kit. <b>The kit does not cross react significantly with mouse, human, rabbit, rhesus monkey, horse, dog, sheep or pig IgM.</b> The concentration of IgM in normal rat serum ranges from 0.2 to 0.5 mg/ml. The assay measures rat IgM in the 0.5-500 ng/ml range. Samples giving rat IgM levels above 500 ng/ml should be diluted in blocking buffer before use. A 1:1,000 to 1:10,000 dilution for normal rat serum or plasma is suggested for best results. Rat IgM will bind to the affinity purified capture antibody coated on the microtiter plate. After appropriate washing steps, peroxidase labeled anti-rat IgM primary antibody binds to the captured protein. Excess antibody is washed away and TMB substrate is used for color development at 450nm. Color development is proportional to the concentration of rat IgM in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rat IgM and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.1 kit5695mol-innov2021
RT-LP-BRSprague Dawley rat brains are frozen, lyophilized, ground and bottled.1000 mg1700mol-innov2021
RT-LP-KDSprague Dawley rat kidneys are frozen, lyophilized, ground and bottled.1000 mg1700mol-innov2021
RT-LP-LRSprague Dawley rat livers are frozen, lyophilized, ground and bottled.1000 mg1700mol-innov2021
RTPARecombinantly produced in insect cells. >85percent single chain, >95percent active.0.1 mg5695mol-innov2021
RTPAKTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of functionally active rat tPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The level of active tPA in normal rat plasma was found to be 1.6 ng/ml. The assay measures active tPA in the 0.1-50 ng/ml range. Samples giving rat tPA levels above 50 ng/ml should be diluted in blocking buffer before use. Samples of plasma in citrate or EDTA may be assayed with this kit. Plasma in heparin is not recommended. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active tPA. If plasma samples were collected in citrate the pH should be brought up to neutral with the 10X TBS provided in the kit. Serum and cell culture media at neutral pH may also be used. Functionally active tPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Complexed tPA will not bind to the PAI-1 and will not be detected by the assay.</b> After appropriate washing steps, anti-rat tPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active tPA in the samples. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br><font color=red>This assay uses an exclusive enzyme capture technology to only detect functionally active protein.</font><br><br> 
<b>Suggested additional reagents</b>: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Mouse-IgG-HRP-Labeled>Secondary Antibody</a><br>
1 kit8415mol-innov2021
RTPAKT-TOTTissue plasminogen activator (tPA) is a serine protease that converts plasminogen to plasmin in the blood fibrinolytic system. It also plays an important role in the nervous system, including the processes of neuronal migration, neurite outgrowth, and neuronal plasticity. tPA has been suggested to have a role in several neuropathological conditions such as cerebral ischemia, seizures, and demyelinating diseases. The sensitive quantitative measurement of total rat tPA antigen in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The level of active tPA in normal rat plasma was found to be 2.5 ng/ml. The assay measures total tPA in the 0.1-50 ng/ml range. Samples giving rat tPA levels above 50 ng/ml should be diluted in blocking buffer before use. Rat tPA will bind to the capture antibody coated on the microtiter plate. <b>Free and complexed tPA will be detected by the assay.</b> After appropriate washing steps, anti-rat tPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of rat tPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rat tPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-tPA-Antigen-Capture-Plate>tPA Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
RTPA-TCRecombinantly produced in insect cells. Activated from single-chain form with immobilized plasmin. >95percent two chain, >95percent active.0.1 mg7480mol-innov2021
RTQPCRThe RealCount One Step RT-qPCR Kit with UNG is ideal for accurate quantification of RNA or DNA in a variety of samples such as whole blood, serum, plasma, urine, saliva, cerebral spinal fluid, feces, and plant. The kit can be used for intercalating dye and probe-based chemistries on a variety of qPCR instruments. Aptamer modified warm start Reality Reverse Transcriptase synthesizes complementary DNA (cDNA) from single-stranded RNA or DNA templates. PCR amplification of the cDNA by TaqTivate Hot Start Taq is monitored in real time. The 4X master mix formulation contains inhibitor reducing buffer components optimized for mammalian tissue samples. Uracil-DNA Glycosylase (UNG) and dUTP are included in the master mix to reduce potential false positive results from carry over contamination. The kit contains Reality Reverse Transcriptase (200U/&micro;l), 4X TaqTivate RT-qPCR Master Mix, DTT solution (100mM), 20X TealReveal Dye, and ROX passive fluorescent reference dye (25&micro;M).<br><br> 
<b>Protocol:</b> The following setup is recommended for a 20&micro;l reaction.<br><br> 
<b>Table 1: Single Step Reaction Setup</b><br> 
<table border=1px padding=5px style=font-size:12px>  
<tr><th width="50%">Component</th><th width="20%">Volume</th><th width="30%">Final Concentration</th></tr> 
<tr><td>TaqTivate Hot Start Master Mix, 4X</td><td>5&micro;l</td><td>1X</td></tr>  
<tr><td>Reality Reverse Transcriptase, 200U/&micro;l*</td><td>0.5&micro;l</td><td>5U/&micro;l</td></tr>  
<tr><td>DTT, 100mM*</td><td>1&micro;l</td><td>5mM</td></tr>  
<tr><td>Target Specific Primers and Probe</td><td>1&micro;l</td><td>1X</td></tr>  
<tr><td>Sample</td><td>X&micro;l</td><td>1pg-100ng</td></tr>  
<tr><td>TealReveal Dye, 20X (if required)</td><td>1&micro;l</td><td>1X</td></tr>  
<tr><td>ROX Reference Dye, 25&micro;M (if required)</td><td>X&micro;l</td><td>See Table 2</td></tr>  
<tr><td>Nuclease Free Water</td><td>QS to 20&micro;l</td><td>-</td></tr> 
</table> 
<p style=font-size:10px>*Reactions must be placed in cycler immediately following completion to maintain the integrity of the Reverse Transcriptase and DTT.</p> 
 
<b>Table 2: Recommended ROX Concentrations</b><br> 
<table border=1px padding=5px style=font-size:12px>  
<tr><th rowspan="2">Type</th><th colspan="2">Instrument</th><th rowspan="2">ROX Final<br>Concentration</th></tr><tr><td>Manufacturer</td><td>Instrument Name</td></tr><tr><td rowspan="6">No ROX</td><td>Roche</td><td>LightCycler 480, LightCycler 2.0</td><td rowspan="6">None</td></tr><tr><td>BioRad</td><td>iCycler, MyiQ, MiQ 2, iQ 5, CFX-96, CFX-384, Chromo4, MJ Opticon, Option2, MiniOpticon</td></tr><tr><td>Qiagen</td><td>Roto-Gene Q, Roto-Gene 3000, Roto-Gene 6000</td></tr><tr><td>Illumina</td><td>Eco RealTime PCR System</td></tr><tr><td>Eppendorf</td><td>Mastercycler realplex</td></tr><tr><td>Cepheid</td><td>Smart Cycler</td></tr><tr><td rowspan="2">Low ROX</td><td>ABI</td><td>7500, 7500 Fast</td><td rowspan="2">30nM</td></tr><tr><td>Stratagene</td><td>MX4000P, MX3000P, MX3005P<br></td></tr><tr><td>High ROX</td><td>ABI</td><td>5700, 7000, 7300, 7700, 7900, 7900HT, 7900HT Fast, StepOne, StepOne plus, Viia7</td><td>300nM</td></tr></table><br> 
 
<b>Table 3: Recommended Cycling Conditions</b><br> 
<table border=1px padding=5px style=font-size:12px> <tr><th>Stage</th><th>Cycling Step</th><th>Cycles</th><th>Temperature</th><th>Holding Time</th></tr>  
<tr><td>1</td><td>UNG Incubation</td><td>1</td><td>25&deg;C</td><td>2min</td></tr> <tr><td>2</td><td>RT Incubation</td><td>1</td><td>55&deg;C</td><td>15min</td></tr> 
<tr><td>3</td><td>Enzyme Activation</td><td>1</td><td>95&deg;C</td><td>2min</td></tr> 
<tr><td rowspan="2">4</td><td rowspan="2">Amplification**</td><td rowspan="2">40</td><td>95&deg;C</td><td>10sec</td></tr> 
<tr><td>60&deg;C</td><td>60sec</td></tr> 
</table> 
<p style=font-size:10px>**Temperature and holding times will depend on primer set used.</p>
200 rxn5015mol-innov2021
RT-TL-BRA freshly-harvested Sprague Dawley rat brain is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
RT-TL-HTA freshly-harvested Sprague Dawley rat heart is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
RT-TL-KDA freshly-harvested Sprague Dawley rat kidney is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
RT-TL-LGA freshly-harvested Sprague Dawley rat lung is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
RT-TL-LRA freshly-harvested Sprague Dawley rat liver is flash-frozen in liquid nitrogen within 30 seconds of removal and stored frozen until lysis. The tissue is ground and thoroughly homogenized at 4C with a freshly prepared modified Radio Immuno Precipitation Assay (RIPA) buffer containing strong protease and phosphatase inhibitor cocktails. The final homogenate is incubated with DNase then clarified by centrifugation at 10,000 g at 4C and stored at -80C. Each lot is quality controlled by determining the protein concentration using a BCA assay and analyzed with SDS-PAGE using Coomassie blue for visualization. Sharp, clear protein bands indicate a quality protein lysate.0.2 mg1785mol-innov2021
RUPAActive two-chain HMW rat urokinase, recombinantly produced in insect cells.0.05 mg5015mol-innov2021
RUPAKTUrokinase plasminogen activator (uPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion/migrations. The sensitive quantitative measurement of functionally active rat uPA in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay measures active uPA in the 0.05-10 ng/ml range. Samples giving rat uPA levels above 10 ng/ml should be diluted in blocking buffer before use. It is important to ensure a platelet free preparation of plasma as platelets can release PAI-1, which in turn could potentially form a complex with active uPA. If plasma samples were collected in citrate the pH should be brought up to neutral with 10X TBS. Serum and cell culture media at neutral pH may also be used. If using kidney extracts that have been extracted using triton X, dialyze to remove the triton X before using in the assay. Detergents such as triton X may interfere with the assay. Functionally active uPA will form a covalent complex with the biotinylated human PAI-1 which is bound to the avidin on the plate. <b>Inactive or complexed uPA will not bind to the PAI-1 and will not be detected by the assay.</b> After appropriate washing steps, anti-rat uPA primary antibody binds to the captured enzyme. Excess antibody is washed away, and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of active uPA in the samples. A standard calibration curve is prepared using dilutions of purified uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br><br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Avidin-Coated-Plate>Avidin Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
RUPAKT-TOTUrokinase plasminogen activator (uPA) is a serine protease that activates plasminogen to plasmin in the blood fibrinolytic system. It is also implicated in events related to cell invasion/migrations. The sensitive quantitative measurement of total rat uPA antigen in plasma and other biological fluid samples is easily performed with this 96 well strip format ELISA kit. The assay measures total uPA in the 0.01-10 ng/ml range. Samples giving rat uPA levels above 10 ng/ml should be diluted in blocking buffer before use. Rat uPA will bind to the capture antibody coated on the microtiter plate. <b>Free and complexed uPA will be detected by the assay.</b> After appropriate washing steps, anti-rat uPA primary antibody binds to the captured protein. Excess primary antibody is washed away and bound antibody is reacted with the secondary antibody conjugated to HRP. Following an additional washing step, TMB substrate is used for color development at 450 nm. Color development is proportional to the concentration of rat uPA in the samples. A standard calibration curve is prepared in blocking buffer using dilutions of purified rat uPA and is measured along with the test samples. All reagents and standards are provided in these ELISA kits.<br>
Suggested additional reagents: <a href=http://www.mol-innov。。com/item/Wash-Buffer-10X-Concentrate>10X Wash Buffer</a>, <a href=http://www.mol-innov。。com/item/TMB-Substrate-for-ELISA>TMB Substrate</a>, <a href=http://www.mol-innov。。com/item/Mouse-uPA-Antigen-Capture-Plate>uPA Antigen Capture Plate</a>, <a href=http://www.mol-innov。。com/item/Anti-Rabbit-IgG-HRP-Labeled>Secondary Antibody</a>
1 kit8415mol-innov2021
RVNPrepared from fresh rat plasma using urea as a denaturant.0.1 mg4590mol-innov2021
RVV-VPurified from Russells Viper Venom. Serine protease that activates single chain Factor V to two chain active Va. This protease is inhibited by diisopropylfluorophosphate (DFP). RVV-V is a single chain glycoprotein and is highly pure and homogenous by SDS-PAGE.1.0 mg9265mol-innov2021
RVV-XPurified from Russells Viper Venom. Zinc dependant endopeptidase that activates Factor X to Xa and Factor IX to IXa-alpha. This protease is inhibited by EDTA and o-phenanthroline. RVV-X is a glycoprotein that consists of two disulfide linked subunits of molecular weights 67kD and 26kD and is highly pure and homogenous by SDS-PAGE.1.0 mg11050mol-innov2021
S119C-L-NBDThis mutant contains a Ser to Cys replacement around the vitronectin binding site. Incorporation of an NBD labels allows for the reporting of binding to vitronectin. This latent fraction is an ideal control for experiments with S119C-NBD.0.5 mg12155mol-innov2021
S119C-NBDThis mutant contains a Ser to Cys replacement around the vitronectin binding site. Incorporation of an NBD labels allows for the reporting of binding to vitronectin.0.5 mg12155mol-innov2021
SARSCOV2GKTSARS-CoV-2 is the novel coronavirus that causes CoronaVirus Disease 2019 (COVID-19). Serological assays are critical for characterizing immune responses to viral infections by determining the presence of viral antigen specific antibodies in infected and recovered patient sera. The sensitive and specific qualitative detection of SARS-CoV-2 specific antibodies of isotype IgG in human serum is easily performed with this 96 well strip format ELISA kit. A 1:51 dilution for serum samples is suggested for best results.<br> 
SARS-CoV-2 specific antibodies in patient samples will bind to the purified recombinant HEK cell derived receptor-binding domain (RBD) of the SARS-CoV-2 spike protein coated on the microtiter plate. After appropriate washing steps, horseradish peroxidase labeled secondary polyclonal anti-human IgG antibody binds to the captured protein. Excess secondary antibody is washed away and TMB substrate is used for color development at 450nm. Samples that exceed a determined cutoff value are designated positive by this assay.<br> 
This kit is provided for <b>in vitro diagnostic (IVD)</b> use only by clinical laboratories certified to perform moderate or high complexity tests in the United States. It is also available labeled for research use only (RUO) upon request. This test has not been reviewed by the FDA. The assay is currently being considered for Emergency Use Authorization. Negative results do not preclude acute SARS-CoV-2 infection. If acute infection is suspected, direct testing for SARS-CoV-2 is necessary. Results from antibody testing should not be used to diagnose or exclude acute SARS-CoV-2 infection. Positive results may be due to past or present infection with non-SARS-CoV-2 coronavirus strains, such as coronavirus HKU1, NL63, OC43, or 229E. Not for the screening of donated blood.<br> 
Produced under license from the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
1 kit8415mol-innov2021
SASDUPAPolyclonal antiserum (host sheep).1.0 ml5695mol-innov2021
SASDUPA-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASDUPA-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASDUPA-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASDUPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASHCII-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHCRPPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHCRP-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHCRP-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHCRP-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHCRP-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHCRP-GF-HTPolyclonal antibody (host sheep).  Affinity purified by immobilized human CRP.0.1 mg3825mol-innov2021
SASHCRP-GF-HT-BIOBiotin labeled polyclonal antibody (host sheep).  Affinity purified by immobilized human CRP.0.1 mg4760mol-innov2021
SASHCTNTPolyclonal antiserum (host rabbit) to human Cardiac Troponin T (cTnT).1.0 ml3825mol-innov2021
SASHCTNT-GFPolyclonal antibody (host sheep) to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHCTNT-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHCTNT-GF-FITCFITC labeled polyclonal antibody (host sheep) to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHCTNT-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human Cardiac Troponin T (cTnT). IgG fraction purified by immobilized Protein G.
<br><br>
1.0 mg4760mol-innov2021
SASHFII-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHFII-GF-HTPolyclonal antibody (host sheep). Affinity purified by immobilized human prothrombin.0.1 mg2975mol-innov2021
SASHFIXPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHFIX-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHFIX-GF-HTAffinity purified polyclonal antibody (host sheep) to human factor IX.0.1 mg4760mol-innov2021
SASHFV-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHFVII-GFPolyclonal antibody to Human Factor VII. Recognizes Human Factor VII and VIIa by ELISA and Western Blot.1.0 mg2975mol-innov2021
SASHFVIII-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHFVIII-GF-AF488Alexa Fluor 488 labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G. Abs: 495, Em: 519.0.05 mg3315mol-innov2021
SASHFX-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHFXIIPolyclonal antiserum (host sheep) to human factor XII.1.0 ml3825mol-innov2021
SASHFXII-GFPolyclonal antibody (host sheep) to human factor XII. IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHFXII-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human factor XII. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHFXII-GF-FITCFITC labeled polyclonal antibody (host sheep) to human factor XII. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHFXII-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human factor XII. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHFXII-GF-HTAffinity purified polyclonal antibody (host sheep) to human factor XII.0.1 mg4760mol-innov2021
SASHFXIII-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHKNGPolyclonal antiserum (host sheep) to human kininogen.1.0 ml3825mol-innov2021
SASHKNG-GFPolyclonal antibody (host sheep) to human kininogen. IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHKNG-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human kininogen. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHKNG-GF-FITCFITC labeled polyclonal antibody (host sheep) to human kininogen. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHKNG-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human kininogen. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHKNG-GF-HTPolyclonal antibody (host sheep). Affinity purified by immobilized human kininogen.0.1 mg3825mol-innov2021
SASHPAIPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHPAI-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHPAI-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPAI-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPAI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPAI-GF-HTPolyclonal antibody (host sheep).  Affinity purified by immobilized human PAI-1.0.1 mg3825mol-innov2021
SASHPC-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHPLGPolyclonal antiserum (host sheep).1.0 ml3400mol-innov2021
SASHPLG-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3400mol-innov2021
SASHPLG-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPLG-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPLG-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPLG-GF-HTPolyclonal antibody (host sheep).  Affinity purified by immobilized human plasminogen.0.1 mg3825mol-innov2021
SASHPLM-GF-HTPolyclonal antibody (host sheep).  Affinity purified by immobilized human plasmin coupled by the active site.0.1 mg3825mol-innov2021
SASHPSAPolyclonal antiserum (host sheep) to human PSA.1.0 ml3825mol-innov2021
SASHPSA-GFPolyclonal antibody (host sheep) to human PSA. IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHPSA-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human PSA. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPSA-GF-FITCFITC labeled polyclonal antibody (host sheep) to human PSA. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPSA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human PSA. IgG fraction purified by immobilized Protein G.1.0 mg4760mol-innov2021
SASHPSA-GF-HTPolyclonal antibody (host sheep) to human PSA. Affinity purified by immobilized human PSA.0.1 mg4760mol-innov2021
SASHPS-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHPZ-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHRAPPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHRAP-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHRAP-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHRAP-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized
Protein G.
1.0 mg5185mol-innov2021
SASHRAP-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHRENPolyclonal antiserum (host sheep) to human renin.1.0 ml5185mol-innov2021
SASHREN-GFPolyclonal antibody (host sheep) to human renin. IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHREN-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human renin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASHREN-GF-FITCFITC labeled polyclonal antibody (host sheep) to human renin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASHREN-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human renin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASHREN-GF-HTPolyclonal antibody (host sheep) to human renin. Affinity purified by immobilized human prorenin. Also available <a href=http://www.mol-innov。。com/item/Immobilized-affinity-purified-sheep-anti-human-prorenin-renin>immobilized to agarose resin</a>.0.1 mg6885mol-innov2021
SASHREN-GF-HT-BIOBiotin labeled polyclonal antibody (host sheep) to human renin. Affinity purified by immobilized human prorenin.0.1 mg6885mol-innov2021
SASHREN-GF-HT-IAffinity purified sheep polyclonal antibody to human renin immobilized on agarose resin. This immobilized antibody is extremely useful for the affinity purification of human prorenin/renin directly from plasma or from cell culture media.1.0 ml5185mol-innov2021
SASHTAFI-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHTF-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHTFPI-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHTHROM-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg2975mol-innov2021
SASHTPAPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHTPA-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHTPA-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHTPA-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHTPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHTPA-GF-HTPolyclonal antibody (host sheep). Affinity purified by immobilized human tPA.0.1 mg7310mol-innov2021
SASHUPAPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASHUPA-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASHUPA-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHUPA-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHUPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASHVWF-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3740mol-innov2021
SASHZPIPolyclonal antiserum (host sheep).1.0 ml5695mol-innov2021
SASHZPI-GFPolyclonal antibody (host sheep) to human Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASHZPI-GF-BIOBiotin labeled polyclonal antibody (host sheep) to human Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASHZPI-GF-FITCFITC labeled polyclonal antibody (host sheep) to human Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASHZPI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to human Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMFIXPolyclonal antiserum (host sheep) to mouse factor IX.1.0 ml5185mol-innov2021
SASMFIX-GFPolyclonal antibody (host sheep) to mouse factor IX. IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMFIX-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse factor IX. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMFIX-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse factor IX. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMFIX-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse factor IX. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMFXPolyclonal antiserum (host sheep) to mouse factor X.1.0 ml5695mol-innov2021
SASMFX-GFPolyclonal antibody (host sheep) to mouse factor X. IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASMFX-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse factor X. IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASMFX-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse factor X. IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASMFX-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse factor X. IgG fraction purified by immobilized Protein G.1.0 mg6630mol-innov2021
SASMFX-GF-HTPolyclonal antibody (host sheep).  Affinity purified by immobilized mouse factor X.0.1 mg5695mol-innov2021
SASMFX-GF-IAPolyclonal antibody to mouse Factor X (Immuno absorbed against human Factor X).0.1 mg5695mol-innov2021
SASMNSPPolyclonal antiserum (host sheep) to mouse neuroserpin (His Tag).1.0 ml5695mol-innov2021
SASMNSP-GFPolyclonal antibody (host sheep) to mouse neuroserpin (His Tag). IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASMNSP-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse neuroserpin (His Tag). IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMNSP-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse neuroserpin (His Tag). IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMNSP-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse neuroserpin (His Tag). IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMNSP-GF-HTPolyclonal antibody (host sheep) to mouse neuroserpin (His Tag). Affinity purified by immobilized mouse neuroserpin.0.1 mg5185mol-innov2021
SASMNSP-GF-HT-BIOBiotin labeled affinity purified polyclonal antibody (host sheep) to mouse neuroserpin (His Tag). Affinity purified by immobilized mouse neuroserpin followed by biotin conjugation.0.5 mg8670mol-innov2021
SASMPCPolyclonal antiserum (host sheep) to mouse protein C and APC.1.0 ml5185mol-innov2021
SASMPC-GFPolyclonal antibody (host sheep) to mouse protein C and APC. IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMPC-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse protein C and APC. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPC-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse protein C and APC. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPC-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse protein C and APC. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPN1Polyclonal antiserum (host sheep).1.0 ml5695mol-innov2021
SASMPN1-GFPolyclonal antibody (host sheep) to mouse protease nexin 1. IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASMPN1-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse protease nexin 1. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPN1-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse protease nexin 1. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPN1-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse protease nexin 1. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPTPolyclonal antiserum (host sheep) to mouse prothrombin and thrombin.1.0 ml5185mol-innov2021
SASMPT-GFPolyclonal antibody (host sheep) to mouse prothrombin and thrombin. IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMPT-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse prothrombin and thrombin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPT-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse prothrombin and thrombin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPT-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse prothrombin and thrombin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMPT-GF-HTPolyclonal antibody (host sheep). Affinity purified by immobilized mouse prothrombin.0.1 mg6035mol-innov2021
SASMPT-GF-HT-BIOBiotin labeled polyclonal antibody (host sheep). Affinity purified by immobilized mouse prothrombin.0.1 mg6885mol-innov2021
SASMTPAPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASMTPA-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASMTPA-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMTPA-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMTPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMTPA-GF-HTPolyclonal antibody (host sheep). Affinity purified by immobilized Mouse tPA.0.1 mg3825mol-innov2021
SASMTPA-GF-HT-BIOBiotin labeled polyclonal antibody (host sheep). Affinity purified by immobilized Mouse tPA.0.5 mg8670mol-innov2021
SASMTPOPolyclonal antiserum (host sheep) to mouse thrombopoietin.1.0 ml5185mol-innov2021
SASMTPO-GFPolyclonal antibody (host sheep) to mouse thrombopoietin. IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMTPO-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse thrombopoietin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMTPO-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse thrombopoietin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMTPO-GF-HRPPeroxidase labeled polyclonal antibody (host sheep) to mouse thrombopoietin. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMUPAPolyclonal antiserum (host sheep).1.0 ml3825mol-innov2021
SASMUPA-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg3825mol-innov2021
SASMUPA-GF-BIOBiotin labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMUPA-GF-FITCFITC labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMUPA-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
SASMUPARPolyclonal antiserum (host sheep) to soluble mouse uPAR, His tagged. Licensed under United States Patent 5,519,120.1.0 ml5695mol-innov2021
SASMUPAR-GFPolyclonal antibody (host sheep) to soluble mouse uPAR, His tagged. IgG fraction purified by immobilized Protein G. Licensed under United States Patent 5,519,120.1.0 mg5695mol-innov2021
SASMUPAR-GF-BIOBiotin labeled polyclonal antibody (host sheep) to soluble mouse uPAR, His tagged. IgG fraction purified by immobilized Protein G. Licensed under United States Patent 5,519,120.1.0 mg6630mol-innov2021
SASMUPAR-GF-FITCFITC labeled polyclonal antibody (host sheep) to soluble mouse uPAR, His tagged. IgG fraction purified by immobilized Protein G. Licensed under United States Patent 5,519,120.1.0 mg6630mol-innov2021
SASMUPAR-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to soluble mouse uPAR, His tagged. IgG fraction purified by immobilized Protein G. Licensed under United States Patent 5,519,120.1.0 mg6630mol-innov2021
SASMZPIPolyclonal antiserum (host sheep).1.0 ml5695mol-innov2021
SASMZPI-GFPolyclonal antibody (host sheep) to mouse Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg5695mol-innov2021
SASMZPI-GF-BIOBiotin labeled polyclonal antibody (host sheep) to mouse Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMZPI-GF-FITCFITC labeled polyclonal antibody (host sheep) to mouse Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASMZPI-GF-HRPHorseradish peroxidase labeled polyclonal antibody (host sheep) to mouse Protein Z-Dependent Protease Inhibitor. IgG fraction purified by immobilized Protein G.1.0 mg6035mol-innov2021
SASRbFBGN-GFPolyclonal antibody (host sheep). IgG fraction purified by immobilized Protein G.1.0 mg5185mol-innov2021
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